Browsing Department of Clinical Science by Author "Vacaru, Ana-Maria"
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Modulation of Unfolded Protein Response Restores Survival and Function of β-Cells Exposed to the Endocrine Disruptor Bisphenol A
Daian, Laura Maria; Tanko, Gabriela; Vacaru, Andrei Mircea; Ghila, Luiza Mihaela; Chera, Simona; Vacaru, Ana-Maria (Journal article; Peer reviewed, 2023-01-19)Diabetes is a metabolic disease that currently affects nearly half a billion people worldwide. β-cells dysfunction is one of the main causes of diabetes. Exposure to endocrine-disrupting chemicals is correlated with increased ... -
Molecular profiling of NOD mouse islets reveals a novel regulator of insulitis onset
Mathisen, Andreas Frøslev; Vacaru, Andrei Mircea; Unger, Lucas; Lamba, Elena Mirela; Mardare, Oana-Ana-Maria; Daian, Laura Maria; Ghila, Luiza Mihaela; Vacaru, Ana-Maria; Chera, Simona (Journal article; Peer reviewed, 2024)Non-obese diabetes (NOD) mice are an established, spontaneous model of type 1 diabetes in which diabetes develops through insulitis. Using next-generation sequencing, coupled with pathway analysis, the molecular fingerprint ...