Blar i Department of Clinical Science på tidsskrift "Molecular Cancer"
Viser treff 1-3 av 3
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Molecular mechanisms of nutlin-3 involve acetylation of p53, histones and heat shock proteins in acute myeloid leukemia
(Peer reviewed; Journal article, 2014-05-21)Background: The small-molecule MDM2 antagonist nutlin-3 has proved to be an effective p53 activating therapeutic compound in several preclinical cancer models, including acute myeloid leukemia (AML). We and others have ... -
Molecular profiling of circulating tumor cells links plasticity to the metastatic process in endometrial cancer
(Peer reviewed; Journal article, 2014-09-27)Background: About 20% of patients diagnosed with endometrial cancer (EC) are considered high-risk with unfavorable prognosis. In the framework of the European Network for Individualized Treatment in EC (ENITEC), we ... -
A non-coding RNA balancing act: miR-346-induced DNA damage is limited by the long non-coding RNA NORAD in prostate cancer
(Journal article; Peer reviewed, 2022-03-22)Background: miR-346 was identified as an activator of Androgen Receptor (AR) signalling that associates with DNA damage response (DDR)-linked transcripts in prostate cancer (PC). We sought to delineate the impact of miR-346 ...