• Brain reactivity during aggressive response in women with premenstrual dysphoric disorder treated with a selective progesterone receptor modulator 

      Kaltsouni, Elisavet; Fisher, Patrick M.; Dubol, Manon; Hustad, Steinar; Lanzenberger, Rupert; Frokjaer, Vibe G.; Wikström, Johan; Comasco, Erika; Sundström-Poromaa, Inger (Journal article; Peer reviewed, 2021)
      Premenstrual dysphoric disorder (PMDD) is a psychiatric condition characterized by late luteal phase affective, cognitive, and physical impairment. The disorder causes significant suffering in about 5% of women in their ...
    • Exploring lithium's transcriptional mechanisms of action in bipolar disorder: a multi-step study 

      Akkouh, Ibrahim; Skrede, Silje; Holmgren, Asbjørn; Ersland, Kari Merete; Hansson, Lars Johan Axel; Bahrami, Shahram; Andreassen, Ole Andreas; Steen, Vidar Martin; Djurovic, Srdjan; Hughes, Timothy (Peer reviewed; Journal article, 2019)
      Lithium has been the first-line treatment for bipolar disorder (BD) for more than six decades. Although the molecular effects of lithium have been studied extensively and gene expression changes are generally believed to ...
    • Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics 

      Lam, Max; Chen, Chia-Yen; Ge, Tian; Xia, Yan; Hill, David W.; Trampush, Joey W.; Yu, Jin; Knowles, Emma; Davies, Gail; Stahl, Eli A.; Huckins, Laura; Liewald, David C.; Djurovic, Srdjan; Melle, Ingrid; Christoforou, Andrea; Reinvang, Ivar; DeRosse, Pamela; Lundervold, Astri J.; Steen, Vidar Martin; Espeseth, Thomas; Räikkönen, Katri; Widen, Elisabeth; Palotie, Aarno; Eriksson, Johan G.; Giegling, Ina; Konte, Bettina; Hartmann, Annette M.; Roussos, Panos; Giakoumaki, Stella; Burdick, Katherine E.; Payton, Antony; Ollier, William; Chiba-Falek, Ornit; Koltai, Deborah; Need, AC; Cirulli, Elizabeth T.; Voineskos, Aristotle N.; Stefanis, Nikos C.; Avramopoulos, Dimitrios; Hatzimanolis, Alex; Smyrnis, Nikolaos; Bilder, Robert M.; Freimer, Nelson B.; Cannon, Tyrone D.; London, Edythe; Poldrack, Russell A.; Sabb, Fred W.; Congdon, Eliza; Conley, Emily Drabant; Scult, Matthew A.; Dickinson, Dwight; Straub, Richard E.; Donohoe, Gary; Morris, Derek; Corvin, Aiden; Gill, Michael; Hariri, Ahmad; Weinberger, Daniel R.; Pendleton, Neil; Bitsios, Panos; Rujescu, Dan; Lahti, Jari; Hellard, Stephanie Francoise Claire Le; Keller, Matthew C.; Andreassen, Ole; Deary, Ian J.; Glahn, David C.; Huang, Hailiang; Liu, Chunyu; Malhotra, Anil K.; Lencz, Todd (Journal article; Peer reviewed, 2021)
      Broad-based cognitive deficits are an enduring and disabling symptom for many patients with severe mental illness, and these impairments are inadequately addressed by current medications. While novel drug targets for ...