Blar i Department of Clinical Science på emneord "Endometrial cancer"
Viser treff 1-7 av 7
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Aneuploidy related transcriptional changes in endometrial cancer link low expression of chromosome 15q genes to poor survival
(Peer reviewed; Journal article, 2017)Aneuploidy is a widely studied prognostic marker in endometrial cancer (EC), however, not implemented in clinical decision-making. It lacks validation in large prospective patient cohorts adjusted for currently standard ... -
Blood Metabolites Associate with Prognosis in Endometrial Cancer
(Peer reviewed; Journal article, 2019-12-14)Endometrial cancer has a high prevalence among post-menopausal women in developed countries. We aimed to explore whether certain metabolic patterns could be related to the characteristics of aggressive disease and poorer ... -
Blood steroid levels predict survival in endometrial cancer and reflect tumor estrogen signaling
(Peer reviewed; Journal article, 2020-02)Objective Blood-based biomarkers are attractive due to ease of sampling and standardized measurement technology, reducing obstacles to clinical implementation. The objective of this study was to evaluate a clinically ... -
DNA ploidy in curettage specimens identifies high-risk patients and lymph node metastasis in endometrial cancer
(Peer reviewed; Journal article, 2015-04-21)Background: Preoperative risk stratification is essential in tailoring endometrial cancer treatment, and biomarkers predicting lymph node metastasis and aggressive disease are aspired in clinical practice. DNA ploidy ... -
High visceral fat percentage is associated with poor outcome in endometrial cancer
(Peer reviewed; Journal article, 2017-10-19)Despite evidence of increased endometrial cancer (EC) risk in obese women, the impact of obesity on clinical and histological phenotype is poorly understood. This study explored abdominal fat volumes and fat distribution ... -
MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk
(Peer reviewed; Journal article, 2017-02-03)Background: The del1518 (rs3730485) polymorphism is an in/del variant in the MDM2 promoter P1. The variant is in complete linkage disequilibrium with MDM2 SNP309 (rs2279744) and has previously been found associated with ... -
What is the best preoperative imaging for endometrial cancer?
(Peer reviewed; Journal article, 2016-04)Although endometrial cancer is surgicopathologically staged, preoperative imaging is recommended for diagnostic work-up to tailor surgery and adjuvant treatment. For preoperative staging, imaging by transvaginal ultrasound ...