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dc.contributor.authorMerialdi, Marioen_US
dc.contributor.authorWidmer, Marianaen_US
dc.contributor.authorGülmezoglu, Ahmet Metinen_US
dc.contributor.authorAbdel-Aleem, Hanyen_US
dc.contributor.authorBega, Georgeen_US
dc.contributor.authorBenachi, Alexandraen_US
dc.contributor.authorCarroli, Guillermoen_US
dc.contributor.authorCecatti, Jose Guilhermeen_US
dc.contributor.authorDiemert, Ankeen_US
dc.contributor.authorGonzalez, Rogelioen_US
dc.contributor.authorHecher, Kurten_US
dc.contributor.authorJensen, Lisa N.en_US
dc.contributor.authorJohnsen, Synnøve Lianen_US
dc.contributor.authorKiserud, Torviden_US
dc.contributor.authorKriplani, Alkaen_US
dc.contributor.authorLumbiganon, Pisakeen_US
dc.contributor.authorTabor, Annen_US
dc.contributor.authorTalegawkar, Sameera A.en_US
dc.contributor.authorTshefu, Antoinetteen_US
dc.contributor.authorWojdyla, Danielen_US
dc.contributor.authorPlatt, Lawrenceen_US
dc.description.abstractBackground: In 2006 WHO presented the infant and child growth charts suggested for universal application. However, major determinants for perinatal outcomes and postnatal growth are laid down during antenatal development. Accordingly, monitoring fetal growth in utero by ultrasonography is important both for clinical and scientific reasons. The currently used fetal growth references are derived mainly from North American and European population and may be inappropriate for international use, given possible variances in the growth rates of fetuses from different ethnic population groups. WHO has, therefore, made it a high priority to establish charts of optimal fetal growth that can be recommended worldwide. Methods: This is a multi-national study for the development of fetal growth standards for international application by assessing fetal growth in populations of different ethnic and geographic backgrounds. The study will select pregnant women of high-middle socioeconomic status with no obvious environmental constraints on growth (adequate nutritional status, non-smoking), and normal pregnancy history with no complications likely to affect fetal growth. The study will be conducted in centres from ten developing and industrialized countries: Argentina, Brazil, Democratic Republic of Congo, Denmark, Egypt, France, Germany, India, Norway, and Thailand. At each centre, 140 pregnant women will be recruited between 8 + 0 and 12 + 6 weeks of gestation. Subsequently, visits for fetal biometry will be scheduled at 14, 18, 24, 28, 32, 36, and 40 weeks (+/− 1 week) to be performed by trained ultrasonographers. The main outcome of the proposed study will be the development of fetal growth standards (either global or population specific) for international applications. Discussion: The data from this study will be incorporated into obstetric practice and national health policies at country level in coordination with the activities presently conducted by WHO to implement the use of the Child Growth Standards.en_US
dc.publisherBioMed Centraleng
dc.rightsAttribution CC BYeng
dc.subjectFetal growtheng
dc.subjectChild developmenteng
dc.subjectGrowth standardseng
dc.titleWHO multicentre study for the development of growth standards from fetal life to childhood: the fetal componenten_US
dc.typePeer reviewed
dc.typeJournal article
dc.rights.holderMario Merialdi et al.; licensee BioMed Central Ltd.
dc.rights.holderCopyright 2014 Merialdi et al.; licensee BioMed Central Ltd
dc.source.journalBMC Pregnancy and Childbirth

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