Blar i Faculty of Mathematics and Natural Sciences på tidsskrift "Biomolecules"
Viser treff 1-4 av 4
-
Enzymatic and Chemical Syntheses of Vacor Analogs of Nicotinamide Riboside, NMN and NAD
(Journal article; Peer reviewed, 2021)It has recently been demonstrated that the rat poison vacor interferes with mammalian NAD metabolism, because it acts as a nicotinamide analog and is converted by enzymes of the NAD salvage pathway. Thereby, vacor is ... -
Insights from cardiopulmonary exercise testing in pediatric patients with hypertrophic cardiomyopathy
(Journal article; Peer reviewed, 2021)The usefulness of cardiopulmonary exercise test (CPET) in adult hypertrophic cardiomyopathy (HCM) patients is well-known, whereas its role in pediatric HCM patients has not yet been explored. The present study investigates ... -
Leaflet Tensions Control the Spatio-Temporal Remodeling of Lipid Bilayers and Nanovesicles
(Journal article; Peer reviewed, 2023)Biological and biomimetic membranes are based on lipid bilayers, which consist of two monolayers or leaflets. To avoid bilayer edges, which form when the hydrophobic core of such a bilayer is exposed to the surrounding ... -
NP-scout: Machine learning approach for the quantification and visualization of the natural product-likeness of small molecules
(Peer reviewed; Journal article, 2019)Natural products (NPs) remain the most prolific resource for the development of small-molecule drugs. Here we report a new machine learning approach that allows the identification of natural products with high accuracy. ...