Blar i Department of Chemistry på utgivelsesdato
Viser treff 1-25 av 556
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Simulating Life at the Periphery: Mechanisms of Membrane Binding and Cargo Extraction by Lipid Transfer Proteins
(Doctoral thesis, 2025-01-09)Biologiske membraner er svært sofistikerte strukturer som består av tusenvis av forskjellige lipidtyper. Deres mekaniske egenskaper bestemmes hovedsakelig av lipidkomposisjonen, noe som gjør det avgjørende for celler å ... -
Exploring FabF as a new target for antibiotic-resistant Pseudomonas aeruginosa: Assay development, fragment screening and hit optimization
(Doctoral thesis, 2024-12-16)Oppdagelsen av antibiotika er utvilsomt blant de største triumfene innen moderne medisin, og har i stor grad forbedret sykdomsforløpet ved de fleste vanlige bakterieinfeksjoner. I dag har triumffanfarene blitt modulert til ... -
Advanced Free Energy Methods in Retrospective and Prospective Drug Design: Application to Serine Proteases
(Doctoral thesis, 2024-12-13)Beregninger av relativ fri bindingsenergi (eng. RBFE) har vokst frem som en foretrukket metode for å veilede kostbare og tidkrevende synteser og andre eksperimenter i legemiddelutvikling på grunn av metodens nærmest ... -
Advancing Discovery of Polar Polycyclic Aromatic Hydrocarbons via UHPLC-HRMS
(Doctoral thesis, 2024-11-29)Industrielle utslipp fra offshore petroleumsvirksomhet introduserer polysykliske aromatiske hydrokarboner (PAH-er) i marine miljøer. Miljøovervåkning av petroleum-relaterte PAH-er i fisk innebærer måling av et sett av deres ... -
Redesigning Clozapine : Development of Clozapine Analogues for the Potential Treatment of Melanoma Brain Metastases
(Doctoral thesis, 2024-11-22)Kreft er den nest vanligste dødsårsaken i Europa. Mangelen på selektiviteten mellom vev danner bivirkninger, uavhengig om behandlingstype. Utvikling av nye behandlinger kan ta opptil 15 år og er kostbart. Gjenbruk av ... -
Exploring the Potential of Biomass Resources Available in Western Norway
(Doctoral thesis, 2024-10-21)Fornybare energikilder som vind, sol, vannkraft og geotermisk energi kan bidra til å erstatte fossile ressurser for å dekke et energibehov, men de kan ikke erstatte vanlig brukte fossilbaserte kjemiske produkter og ... -
Source and fate of ultra-short-chain PFAS in AFFF-impacted water and biota
(Master thesis, 2024-06-24) -
Thermal stability of polyphenols and carotenoids from Laminaria hyperborea
(Master thesis, 2024-06-03)The green shift, and the focus on an increased blue bioeconomy, has stimulated the growth of sustainable production lines for marine bioactive products for food-, feed-, cosmetics-, and -pharmaceutical industries. Norway ... -
Synthesis and Comparative Analysis of Carbon Dots: A Study on Continuous Flow, Microwave, and Furnace Methods
(Master thesis, 2024-06-03)Karbonprikker (eng.: Carbon Dots) ble først oppdaget i 2004, og siden da har de tiltrukket seg betydelig oppmerksomhet på grunn av deres unike egenskaper, som gjør dem egnet for et bredt spekter av bruksområder. I denne ... -
Kartlegging av LtL-prosessen ved bruk av ulike biomaterialerog geokjemisk analyser.
(Master thesis, 2024-06-03) -
Trace element composition of Norway lobster (Nephrops norvegicus) in the proximity of fish farms
(Master thesis, 2024-06-03)The aquaculture industry in Norway is expected to grow with potential impact on the environment. The common seafood delicacy Norway lobster (Nephrops norvegicus) was studied to see how the vicinity to aquaculture might ... -
Exploring gas adsorption properties and phase transitions of two M(tppo) metal-organic frameworks
(Master thesis, 2024-06-03)Separation and storage of gases is of interest to the global society in order to minimize emission of greenhouse gases and utilize these gases as resources in their pure form in the chemical industry. This work considers ... -
Videregående elevers opplevelse av mappevurdering i naturfag
(Master thesis, 2024-06-03)Vurdering er en sentral del i utdanningen i den norske skolen. Gjennom den nye læreplanen er det et mål å legge til rette for blant annet dybdelæring og aktiv læring. Dermed blir det viktig at elevene får utføre utforskende ... -
Qualitative and quantitative analyses of unbound phenolic compounds from pollen grains of pine (Pinus uncinata)
(Master thesis, 2024-06-03)The research in this master project is performed within an interdisciplinary RCN (The Research Council of Norway) research project (QUEST-UV: Quantitative estimates of past UV-B irradiance from fossil pollen) and includes ... -
Glucuronic Acid in Kombucha: A Multivariate Investigation of White, Green, and Black Tea Kombucha Combining Sensory Profiling, Mass Spectrometry, and Nuclear Magnetic Resonance Spectroscopy
(Master thesis, 2024-06-03)Kombucha, en fermentert te som er blitt kjent for sine potensielle helsefordeler, har økt i popularitet i takt med den økende interessen for funksjonelle matvarer. Til tross for påstander om oppkvikkende og avgiftende ... -
The Distribution and Elimination of Lufenuron in Atlantic Salmon (Salmo salar)
(Master thesis, 2024-06-03)Salmon lice (Lepeophtheirus salmonis) are a growing problem in the Norwegian aquaculture industry with an estimated annual cost of sea lice management of 525 million USD in 2019 in Norway. Numerous lice treatments exist, ... -
Investigation and Application of pH-Sensitive Materials as Sensing Elements in Optical Fibre pH-Sensor Systems
(Master thesis, 2024-06-03) -
Investigating the Impact of Fermentation on Polyphenolic Content in Cultivated Sugar Kelp (Saccharina latissima): A Comprehensive Study
(Master thesis, 2024-06-03)Seaweeds, classified as macroalgae, are a marine bioresource garnering global attention, primarily due to the increasing demand for new sustainable bioresources. Seaweeds are rich in a variety of bioactive compounds that ... -
Optimized magnetic resonance spectroscopy of 2-hydroxyglutarate
(Master thesis, 2024-06-03)In recent years, non-invasive detection of 2-hydroxyglutarate (2HG) using 1H − MRS has emerged as a promising method for differentiating IDH mutant and wild-type brain tumors. However, reliable detection and quantification ... -
Development of a System for Microdosimetric Assessment of Clinical Proton Treatment Plans via Proton Energy Spectra
(Master thesis, 2024-06-03)Purpose: The biological effectiveness of proton radiation depends on variables beyond the absorbed dose. In particular, the dose deposition on a micrometer scale may be relevant for subcellular structures such as DNA. ... -
Exploring the function of mammalian Adenosine Deaminase 2, a novel anti-inflammatory glycoprotein of the macrophage lysosome
(Master thesis, 2024-06-03)Deficiency of Adenosine Deaminase 2 (DADA2) is an autosomal recessive autoinflammatory disease currently standing without sufficient treatment. The main reason for the lack of targeted therapy is the lack of understanding ... -
Bowel motion and implications for online adaptive radiotherapy of rectal cancer
(Master thesis, 2024-06-03)Purpose: Radiotherapy (RT) of rectal cancer inevitably involves irradiation of the healthy bowel due to its close proximity. Reduction of excessive dose to the bowelis part of the radiation treatment plan optimisation. ... -
Quality Assurance of Medical Mass Spectrometry with Artificial Intelligence
(Master thesis, 2024-06-03)Medical liquid chromatography-mass spectrometry (LC-MS) analysis requires technical quality assessment before results can be reported. Quality requirements involve technical validation of instrument parameters for each ... -
Automated segmentation of CT lung lesions using Deep Learning
(Master thesis, 2024-06-03)Purpose: Lung cancer, both primary and secondary, has one of the highest cancer-related mortality rates. This form of cancer can be detected using the high-resolution medical imaging technique, Computed Tomography (CT). ... -
The Effect of Electroconvulsive Therapy and Transcranial Magnetic Stimulation on Brain Volumes and Perfusion in Depression
(Master thesis, 2024-06-03)Major depressive disorder is a common mental disorder and is characterized by experiencing a depressed mood and thoughts of hopelessness or suicide. Bipolar disorder is a mental illness that causes changes in a person’s ...