Browsing Faculty of Medicine by Title
Now showing items 646-665 of 8740
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B cell specificity and pattern in primary Sjögren’s syndrome - Studies in humans and a murine model
(Doctoral thesis, 2014-04-30)Sjögren’s syndrome (SS) is a chronic autoimmune disease characterised by focal inflammation of exocrine glands, particularly salivary and lacrimal glands. Here, mononuclear cells, including B cells, infiltrate the glands, ... -
B cells and autoantibodies in AIRE deficiency
(Journal article; Peer reviewed, 2021)Autoimmune polyendocrine syndrome type 1 (APS-1) is a rare but severe monogenetic autoimmune endocrine disease caused by failure of the Autoimmune Regulator (AIRE). AIRE regulates the negative selection of T cells in the ... -
B vitamin and iron status during infancy
(Doctoral thesis, 2015-01-30)Adequate nutrition during infancy is essential to ensure normal growth and development. Since 2001, World Health Organization (WHO) has recommended exclusive breast-feeding for the first 6 months of life, which puts great ... -
B vitamin treatments modify the risk of myocardial infarction associated with a MTHFD1 polymorphism in patients with stable angina pectoris
(Peer reviewed; Journal article, 2016-06)Background: Methylenetetrahydrofolate dehydrogenase (MTHFD1) catalyzes three sequential reactions that metabolize derivatives of tetrahydrofolate (THF) in folate-dependent one-carbon metabolism. Impaired MTHFD1 flux has ... -
The B-lymphocyte chemokine CXCL13 in the cerebrospinal fluid of children with Lyme neuroborreliosis: associations with clinical and laboratory variables
(Peer reviewed; Journal article, 2019)Background: The B-lymphocyte chemokine CXCL13 is increasingly considered as a useful early phase diagnostic marker of Lyme neuroborreliosis (LNB). However, the large variation in level of CXCL13 in the cerebrospinal fluid ... -
B-type natriuretic peptide and high sensitive C-reactive protein predict 2-year all cause mortality in chest pain patients: a prospective observational study from Salta, Argentina
(Peer reviewed; Journal article, 2011-09-29)Background: Several mechanisms are involved in the pathophysiology of the Acute Coronary Syndrome (ACS). We have addressed whether B-type natriuretic peptide (BNP) and high-sensitive C-reactive protein (hsCRP) in admission ... -
B-type natriuretic peptide expression and cardioprotection is regulated by Akt dependent signaling at early reperfusion
(Peer reviewed; Journal article, 2015-04)Exogenously administered B-type natriuretic peptide (BNP) has been shown to offer cardioprotection through activation of particulate guanylyl cyclase (pGC), protein kinase G (PKG) and KATP channel opening. The current study ... -
B-vitamin Treatment Modifies the Mortality Risk Associated with Calcium Channel Blockers in Patients with Suspected Stable Angina Pectoris: A Prospective Cohort Study
(Journal article; Peer reviewed, 2023)Background Calcium channel blockers (CCBs) are used for the treatment of cardiovascular disease (CVD), including angina pectoris, and hypertension; however, the effect on survival remains uncertain. CCBs impair fibrinolysis ... -
“Back to Eden”: An explorative qualitative study on traditional medicine use during pregnancy among selected women in Lusaka Province, Zambia
(Journal article; Peer reviewed, 2020)Background and purpose: No qualitative study on traditional medicine use among Zambian pregnant women has ever been conducted. Accordingly, this study was performed to explore the perceptions, motivations and experiences ... -
Bacteraemia among severely malnourished children infected and uninfected with the human immunodeficiency virus-1 in Kampala, Uganda
(Peer reviewed; Journal article, 2006-11-07)Background: To establish the magnitude of bacteraemia in severely malnourished children, and describe the types of bacteria and antimicrobial sensitivity by HIV status. Method: Isolates were recovered from 76 blood specimens. ... -
Bacteraemia, Malaria, and Case Fatality Among Children Hospitalized With Fever in Dar es Salaam, Tanzania
(Journal article; Peer reviewed, 2020)Background: Febrile illness is the commonest cause of hospitalization in children <5 years in sub-Saharan Africa, and bacterial bloodstream infections and malaria are major causes of death. Methods: From March 2017 to ... -
Bacteria and fungi in acute cholecystitis. A prospective study comparing next generation sequencing to culture
(Peer reviewed; Journal article, 2020)Objectives: Guidelines for antibiotic treatment of acute cholecystitis are based on studies using culture techniques for microbial identification. Microbial culture has well described limitations and more comprehensive ... -
The bacterial aetiology of pleural empyema. A descriptive and comparative metagenomic study
(Peer reviewed; Journal article, 2019)Objectives: The view of pleural empyema as a complication of bacterial pneumonia is changing because many patients lack evidence of underlying pneumonia. To further our understanding of pathophysiological mechanisms, we ... -
Bacterial contamination of coffee and personal exposure to inhalable dust and endotoxin in primary coffee processing factories in Ethiopia
(Journal article; Peer reviewed, 2023)Introduction and objective: Endotoxins from gram-negative bacteria might be released when the coffee cherries are processed and may cause respiratory health problems among workers in the coffee industry. The relationship ... -
Bacterial Findings in Infected Hip Joint Replacements in Patients with Rheumatoid Arthritis and Osteoarthritis: A Study of 318 Revisions for Infection Reported to the Norwegian Arthroplasty Register
(Peer reviewed; Journal article, 2012)High rates of Staphylococcus aureus are reported in prosthetic joint infection (PJI) in rheumatoid arthritis (RA). RA patients are considered to have a high risk of infection with bacteria of potentially oral or dental ... -
The Bacterial Preparation OK432 Induces IL-12p70 Secretion in Human Dendritic Cells in a TLR3 Dependent Manner
(Peer reviewed; Journal article, 2012-02-21)Dendritic cells (DC) used in therapeutic cancer immunotherapy have to be able to stimulate T cells resulting in an immune response that can efficiently target the cancer cells. One of the critical hurdles has been the lack ... -
The badness of death and priorities in health
(Peer reviewed; Journal article, 2016-04-14)Background The state of the world is one with scarce medical resources where longevity is not equally distributed. Given such facts, setting priorities in health entails making difficult yet unavoidable decisions about ... -
Bag-in-the-lens intraocular lens in paediatric cataract surgery: intraoperative and postoperative outcomes
(Journal article; Peer reviewed, 2021)Purpose: To report intra- and postoperative surgical outcome using the bag-in-the-lens (BIL) technique in paediatric cataract surgery. Methods: In a retrospective case series, we studied the outcomes of children aged ... -
Baked cod consumption delayed the development of kidney and liver dysfunction and affected plasma amino acid concentrations, but did not affect blood pressure, blood glucose or liver triacylglycerol concentrations in obese fa/fa Zucker rats.
(Journal article; Peer reviewed, 2021)Obesity is associated with changes in amino acid metabolism, and studies show that ingestion of fish proteins influence amino acid composition in plasma and urine, in addition to affecting risk factors for metabolic syndrome. ... -
Bakers’ rhinitis : diagnostic criteria, flour dust exposure, mucosal inflammation, IgE sensitization, and relation to lower airways
(Doctoral thesis, 2008-01-16)This thesis is the results of a cross-sectional epidemiological study undertaken in the period from March 2000 to January 2002 on bakery workers in 6 bakeries in Bergen, Norway. The aims were to study the consequences of ...