Browsing Faculty of Medicine by Title
Now showing items 977-996 of 9239
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C- reactive protein in schizophrenia-spectrum disorders; relationship to cognitive functions and medications
(Doctoral thesis, 2019-12-05)Background: Schizophrenia spectrum disorders are severe mental illnesses characterized by psychotic symptoms, cognitive dysfunction and functional decline. Cognitive impairments have been recognized as core features of ... -
C/EBPB-dependent adaptation to palmitic acid promotes tumor formation in hormone receptor negative breast cancer
(Journal article; Peer reviewed, 2022)Epidemiological studies have established a positive association between obesity and the incidence of postmenopausal breast cancer. Moreover, it is known that obesity promotes stem cell-like properties of breast cancer ... -
C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease
(Peer reviewed; Journal article, 2017-07-31)The pan lymphocyte marker CD45 exists in various isoforms arising from alternative splicing of the exons 4, 5 and 6. While naïve T cells express CD45RA translated from an mRNA containing exon 4, exons 4–6 are spliced out ... -
CA-125 levels are predictive of survival in low-grade serous ovarian cancer—A multicenter analysis
(Journal article; Peer reviewed, 2022-04-13)Objective: Studies on low-grade serous ovarian cancer (LGSC) are limited by a low number of cases. The aim of this study was to define the prognostic significance of age, stage, and CA-125 levels on survival in a ... -
Ca-EDTA restores the activity of ceftazidime-avibactam or aztreonam against carbapenemase-producing Klebsiella pneumoniae infections
(Journal article; Peer reviewed, 2023)Developing an effective therapy to overcome carbapenemase-positive Klebsiella pneumoniae (CPKp) is an important therapeutic challenge that must be addressed urgently. Here, we explored a Ca-EDTA combination with aztreonam ... -
Cabozantinib is effective in melanoma brain metastasis cell lines and affects key signaling pathways
(Journal article; Peer reviewed, 2021-11-14)Melanomas have a high potential to metastasize to the brain. Recent advances in targeted therapies and immunotherapies have changed the therapeutical landscape of extracranial melanomas. However, few patients with melanoma ... -
CACNA1D overexpression and voltage-gated calcium channels in prostate cancer during androgen deprivation
(Journal article; Peer reviewed, 2023)Prostate cancer is often treated by perturbing androgen receptor signalling. CACNA1D, encoding CaV1.3 ion channels is upregulated in prostate cancer. Here we show how hormone therapy affects CACNA1D expression and CaV1.3 ... -
Cadmium, lead and mercury in Norwegian obese patients before and 12 months after bariatric surgery
(Peer reviewed; Journal article, 2019)Purpose Previous studies have suggested a role for the toxic elements lead (Pb), mercury (Hg) and cadmium (Cd) in the development of insulin resistance and hypertension. Increased blood Pb levels have been reported after ... -
Caesarean Delivery and Women’s Health: Population-Based Studies : Trends, Offspring Birthweight, Fecundability and Maternal Cardiovascular Disease Mortality
(Doctoral thesis, 2024-02-22)Bakgrunn: Globalt har det vært en økning i antall fødsler forløst med keisersnitt. Keisersnitt er assosiert med ugunstige utfall både for mor og barn, og det er derfor viktig å studere endring i keisersnitt over tid og ... -
Caesarean section rates analysed using Robson’s 10-Group Classification System: a cross-sectional study at a tertiary hospital in Ethiopia
(Journal article; Peer reviewed, 2020)Objective The aim of this study was to assess the caesarean section (CS) rates using Robson’s 10-Group Classification System among women who gave birth at Hawassa University Referral Hospital in southern Ethiopia. Design ... -
Calcium Channel Blockers and the Risk of Exacerbation in Patients with Chronic Obstructive Pulmonary Disease: A Nationwide Study of 48,488 Outpatients
(Journal article; Peer reviewed, 2023)Patients with chronic obstructive pulmonary disease (COPD) are prone to developing arterial hypertension, and many patients are treated with the calcium channel blocker amlodipine. However, it remains unclear whether using ... -
A calibration study of SAPS II with Norwegian intensive care registry data
(Peer reviewed; Journal article, 2014-05-12)Background Mortality prediction is important in intensive care. The Simplified Acute Physiology Score (SAPS) II is a tool for predicting such mortality. However, the original SAPS II is poorly calibrated to current intensive ... -
Call for better response evaluation after neoadjuvant therapy in pancreatic cancer
(Journal article; Peer reviewed, 2023) -
Calprotectin (S100A8/A9) and S100A12 in inflammatory arthritis : clinical and epidemiological studies of rheumatoid and psoriatic arthritis
(Doctoral thesis, 2007-12-14)Rheumatoid- and psoriatic arthritis (RA and PsA) are the two most prevalent inflammatory joint diseases in Caucasian. Different biomarkers in peripheral blood may contribute in the diagnostic and prognostic process, as ... -
Calprotectin (S100A8/A9) has the strongest association with ultrasound-detected synovitis and predicts response to biologic treatment: results from a longitudinal study of patients with established rheumatoid arthritis
(Peer reviewed; Journal article, 2017-01-12)Background: Calprotectin (S100A8/A9 or MRP8/14) and S100A12 (leukocyte-derived proteins), interleukin 6 (IL-6) and vascular endothelial growth factor (VEGF) are markers of inflammation and angiogenesis. Ultrasound (US) is ... -
Calprotectin, a sensitive marker of inflammation, is robustly assessed in plasma from patients with early or established rheumatoid arthritis by use of different laboratory methods
(Journal article; Peer reviewed, 2023)Calprotectin (S100A8/S100A9, MRP8/MRP14) is a major leukocyte protein found to be more sensitive than C-Reactive Protein (CRP) and Erythrocyte Sedimentation Rate (ESR) as a marker of inflammation in patients with rheumatoid ... -
Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines
(Peer reviewed; Journal article, 2009-11-13)Background: An organic extract of the recreational herb khat (Catha edulis Forsk.) triggers cell death in various leukemia cell lines in vitro. The chemotherapeutics camptothecin, a plant alkaloid topoisomerase I inhibitor, ... -
Can 'early programming' be partly explained by smoking? Results from a prospective, population-based cohort study
(Peer reviewed; Journal article, 2015-01)Background: Numerous studies have focused the association between low birthweight and later disease. Our objective was to study the association between birthweight and later adult smoking and thereby explore a possible ... -
Can a structured electronic medical record with decision-making support improve nursing home quality? Healthcare administration through structured records
(Doctoral thesis, 2013-05-31)Background: Nursing homes face challenges in the coming years due to the increased number of elderly. A new law in force from Jan 2012 (“Samhandlingsreformen”) places more responsibilities on the counties running the nursing ... -
Can adults with cerebral palsy perform and beneft from ballistic strength training to improve walking outcomes? A mixed methods feasibility study
(Journal article; Peer reviewed, 2021)Background: Power bursts of hips and ankle plantar flexors are prerequisites to walking propulsion. However, these power bursts are reduced during gait for persons with cerebral palsy (CP) and mainly in the ankle plantar ...