Blar i Faculty of Medicine på tittel
Viser treff 3385-3404 av 4906
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p53 protein biosignatures in acute myeloid leukemia
(Doctoral thesis, 2006-03-10)p53 is a tumor suppressor protein often regarded as the guardian of the genome. It is a highly connected protein involved in many signaling processes in the cell. The inactivation of p53 through genetic mutations in TP53 ... -
Paediatric HIV-1 infection in Uganda. Natural history and early antiretroviral treatment response
(Doctoral thesis, 2011-10-07)Paediatric HIV-1 infection remains a major problem for sub-Saharan Africa with over 1300 new infections daily. Infected children have a high mortality with 50% dying by 2 years of age. Access to antiretroviral therapy (ART) ... -
Pain and pain tolerance in whiplash-associated disorders:A population-based study
(Peer reviewed; Journal article, 2015)Background: Pain is a cardinal symptom in individuals with whiplash-associated disorders (WAD). We aimed to compare pain characteristics between individuals with WAD and individuals reporting chronic pain from other causes, ... -
Pain and physical function among nursing home patients and people with dementia. Cross-sectional analyses from the COSMOS-trial
(Master thesis, 2018-08-24)Background: Previous studies have shown how nursing home patients have poor physical functioning and are largely care dependent in activities of daily life. These patients have a high prevalence of pain and are mainly ... -
Pain management in patients with dementia
(Peer reviewed; Journal article, 2013-10-31)There are an estimated 35 million people with dementia across the world, of whom 50% experience regular pain. Despite this, current assessment and treatment of pain in this patient group are inadequate. In addition to the ... -
Pain relief from nonpharmacological interventions in the intensive care unit: A scoping review
(Journal article; Peer reviewed, 2020)Aims and Objectives: To describe what is known from the existing literature on nonpharmacological interventions targeting pain in patients admitted to the ICU. Background: Patients receiving intensive care nursing are ... -
Pain, coping, and barriers to pain management in outpatients with cancer
(Doctoral thesis, 2009-01-20) -
A painful experience of limited understanding: healthcare professionals’ experiences with palliative care of people with severe dementia in Norwegian nursing homes
(Peer reviewed; Journal article, 2018-02-13)Background: People dying with dementia have significant healthcare needs, and palliative care, with its focus on comfort and quality of life, should be made available to these patients. The aim of this study was to explore ... -
Palliasjon på sykehjem: Hva gjør helsepersonell i møte med alvorlig syke og døende pasienter - og hvordan formes deres handlinger?
(Master thesis, 2013-05-13)Masteravhandlingen har fokus på helsearbeideres praksiserfaringer i møte med alvorlig syke og døende pasienter på sykehjem. Hensikten er å beskrive, forstå og forklare hva helsepersonell gjør når de utfører palliativ ... -
Palliative care services at Nkhoma, rural Malawi – A qualitative exploration of experiences of the care providers and the recipients
(Master thesis, 2020-08-29)Background and purpose Palliative care is rapidly developing in Africa, but still many people live and die in pain because the coverage and the capacity to meet the needs are low. Morphine is a potent opioid pain killer, ... -
A pan-European survey of research in end-of-life cancer care
(Peer reviewed; Journal article, 2010-11-30)Background To date, there is no coordinated strategy for end-of-life (EOL) cancer care research in Europe. The PRISMA (Reflecting the Positive Diversities of European Priorities for Research and Measurement in End-of-life ... -
Pandemic influenza vaccines - the challenges
(Peer reviewed; Journal article, 2009-12-03)Recent years’ enzootic spread of highly pathogenic H5N1 virus among poultry and the many lethal zoonoses in its wake has stimulated basic and applied pandemic vaccine research. The quest for an efficacious, affordable and ... -
The PAr index, an indicator reflecting altered vitamin B-6 homeostasis, is associated with long-term risk of stroke in the general population: the Hordaland Health Study (HUSK)
(Peer reviewed; Journal article, 2018-01)Background: Vitamin B-6 homeostasis is altered during inflammation and immune activation. It is unknown whether altered vitamin B-6 homeostasis is associated with the risk of stroke. Objective: We investigated the relation ... -
Paracrine Effects of Mesenchymal Stem Cells on Dental Tissues - in vitro and in vivo studies
(Doctoral thesis, 2016-03-17)In regenerative medicine or dentistry, it has been reported that stem cells induce the regenerative potential of injured tissues. In the present thesis, pulp and periapical tissues as well as pulpal cells were exposed to ... -
Paraneoplastic CDR2 and CDR2L antibodies affect Purkinje cell calcium homeostasis
(Peer reviewed; Journal article, 2014-12)Paraneoplastic cerebellar degeneration (PCD) is characterized by loss of Purkinje cells (PCs) associated with progressive pancerebellar dysfunction in the presence of onconeural Yo antibodies. These antibodies recognize ... -
Paraneoplastic cerebellar degeneration: Characterizing the Yo antibody antigens
(Doctoral thesis, 2021-03-16)Background: The pathogenesis of paraneoplastic cerebellar degeneration (PCD) with Yo-antibodies is unclear. The disease is generally accepted as immune-mediated, but whether the Yo antibodies themselves are pathogenic ... -
Paraneoplastic syndrome-associated neuronal antibodies in adult ADHD
(Peer reviewed; Journal article, 2015-09-01)A high seroprevalence of Yo antibodies targeting cerebellar Purkinje cells was recently reported in children with attention deficit/hyperactivity disorder (ADHD). We investigated the presence of 8 paraneoplastic neurological ... -
Parent psychological wellbeing in a single-family room versus an open bay neonatal intensive care unit
(Peer reviewed; Journal article, 2019-11-05)Background Studies of parents’ psychological well-being in single-family rooms in neonatal intensive care units have shown conflicting results. Aims To compare emotional distress in the form of depression, anxiety, stress ... -
Parent-child communication about sexual issues in Zambia: a cross sectional study of adolescent girls and their parents
(Journal article; Peer reviewed, 2020)Background Parent-child communication about sexual issues can reduce risky sexual behaviour amongst adolescents. Risky sexual behaviour is of concern in sub-Saharan Africa where the prevalence of early pregnancy, unsafe ... -
Parent-of-origin-environment interactions in case-parent triads with or without independent controls
(Peer reviewed; Journal article, 2018-03)With case–parent triad data, one can frequently deduce parent of origin of the child's alleles. This allows a parent‐of‐origin (PoO) effect to be estimated as the ratio of relative risks associated with the alleles inherited ...