Blar i Faculty of Medicine på tittel
Viser treff 1890-1909 av 9415
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Cytokine profiles in inflammation
(Doctoral thesis, 2017-06-16)Inflammation is a complex tissue response to harmful stimuli such as microorganisms, damaged or dead cells, or irritants. The inflammatory process can be initiated by many different diseases, including thromboses, neoplastic ... -
Cytokine release syndrome in the immunotherapy of hematological malignancies: The biology behind and possible clinical consequences
(Journal article; Peer reviewed, 2021)Cytokine release syndrome (CRS) is an acute systemic inflammatory syndrome characterized by fever and multiple organ dysfunction associated with (i) chimeric antigen receptor (CAR)-T cell therapy, (ii) therapeutic antibodies, ... -
The cytokine-mediated crosstalk between primary human acute myeloid cells and mesenchymal stem cells alters the local cytokine network and the global gene expression profile of the mesenchymal cells
(Peer reviewed; Journal article, 2015-11)Interactions between acute myeloid leukemia (AML) blasts and neighboring stromal cells are important for disease development and chemosensitivity. However, the molecular mechanisms involved in the cytokine-mediated crosstalk ... -
Cytokines - possible biomarkers for headache syndromes, with special reference to migraine
(Master thesis, 2011-05-31)Background: The trigeminovascular theory suggests that neurogenic inflammation and cytokines play an important role in migraine pathophysiology. Previous studies have linked different cytokines to migraine pathogenesis, ... -
Cytokines in Renal Cell Carcinoma : With emphasis on Vascular Endothelial Growth Factor (VEGF) and Interleukin 6 (IL-6)
(Doctoral thesis, 2021-11-12)Aims: In the first three papers we aimed to investigate if different circulating cytokines in blood drawn preoperatively can predict outcome after surgery in patients with renal cell carcinoma (RCC). The last paper aimed ... -
Cytokines, adhesion molecules, and matrix metalloproteases as predisposing, diagnostic, and prognostic factors in venous thrombosis
(Peer reviewed; Journal article, 2018-05-22)The inflammatory response is a well-established part of, and a prerequisite for, venous thrombosis. To better understand the pathophysiology of venous thrombosis and to identify improved diagnostic biomarkers, further ... -
Cytotoxicity of eluates from denture base materials
(Master thesis, 2015-01-26)Background: Some patients do not tolerate polymethylmethacrylate-based (PMMA) dentures. Polyamide as an alternative to PMMA has, however, not been well documented regarding to biocompatibility and cytotoxicity. Aim: The ... -
Dactolisib (NVP-BEZ235) toxicity in murine brain tumour models
(Peer reviewed; Journal article, 2016-08-19)Background: Glioblastomas (GBMs) are highly malignant brain tumours with a poor prognosis, and current cytotoxic regimens provide only a limited survival benefit. The PI3K/Akt/mTOR pathway has been an attractive target for ... -
Daily Folic Acid and/or Vitamin B12 Supplementation Between 6 and 30 Months of Age and Cardiometabolic Risk Markers After 6–7 Years: A Follow-Up of a Randomized Controlled Trial
(Journal article; Peer reviewed, 2023)Background Deficiencies of vitamin B12 and folate are associated with elevated concentrations of metabolic markers related to CVDs. Objectives We investigated the effect of supplementation of vitamin B12 with or ... -
Daily intake of protein from cod residual material lowers serum concentrations of nonesterified fatty acids in overweight healthy adults: A randomized double-blind pilot study
(Peer reviewed; Journal article, 2018-06-05)Improved process technologies have allowed fishing vessels to utilize residuals from cod fillet production (head, backbone, skin, cuttings, and entrails) and convert this to high-quality protein powders for human consumption. ... -
Daily variation in physical activity during mechanical ventilation and stay in the intensive care unit
(Journal article; Peer reviewed, 2023)Background Early mobilisation of mechanically ventilated patients during their stay at an intensive care unit (ICU) can improve physical recovery. Yet, an objective and specified description of physical activities while ... -
Damage tolerance of six dental zirconias with different translucencies
(Journal article; Peer reviewed, 2020)Purpose: High-translucent dental zirconia has been introduced as a suitable material for anterior monolithic restorations. The material composition differs from traditional 3Y-TZP both with regard to yttria content and ... -
Dampness and mold at home and at work and onset of insomnia symptoms, snoring and excessive daytime sleepiness
(Journal article; Peer reviewed, 2020)Aim To investigate whether exposure to dampness and mold at home and at work induce sleep disturbances and daytime sleepiness among adults. Materials and methods Associations between onset of sleep disturbances and ... -
Dansk sygepleje, højere uddannelse og sygeplejerskernes forskning. Et studie af danske sygeplejerskers uddannelsesvej fra titlen sygeplejerske/professionsbachelor til forskeruddannelse/ph.d
(Journal article; Peer reviewed, 2023)Artiklen analyserer hvordan sygeplejerskeforskningen har udviklet sig i perioden 1998 – 2017. Undersøgelsens udgangspunkt er K. A. Petersens Bourdieu-inspirerede arbejde fra 1997. Gennem opgørelser af ph.d.-afhandlingers ... -
Dasatinib induces fast and deep responses in newly diagnosed chronic myeloid leukaemia patients in chronic phase: Clinical results from a randomised phase-2 study (NordCML006)
(Peer reviewed; Journal article, 2014-09-13)We randomised 46 newly diagnosed patients with chronic myeloid leukaemia (median age 56) to receive dasatinib 100 mg QD or imatinib 400 mg QD and report outcome as an intention-to-treat analysis with 36 months follow-up. ... -
Data entry quality of double data entry vs automated form processing technologies: A cohort study validation of optical mark recognition and intelligent character recognition in a clinical setting
(Journal article; Peer reviewed, 2020)Background and Aims Patient-reported outcome measures (PROMs) are increasingly used in health services. Paper forms are still often used to register such data. Manual double data entry (DDE) has been defined as the gold ... -
Data quality and practical challenges of thyroid volume assessment by ultrasound under field conditions - observer errors may affect prevalence estimates of goitre
(Peer reviewed; Journal article, 2010-12-14)Background The ultrasonographic estimation of thyroid size has been advocated as being more precise than palpation to diagnose goitre. However, ultrasound also requires technical proficiency. This study was conducted among ... -
DC/TMD Examiner Protocol: Longitudinal Evaluation on Interexaminer Reliability
(Peer reviewed; Journal article, 2018-09-26)Objectives. The objectives of this study were to assess the interexaminer agreement between one “reference” (gold standard) and each of two examiners, using the DC/TMD examination method, Axis I and to evaluate whether a ... -
DCLK1 Variants Are Associated across Schizophrenia and Attention Deficit/Hyperactivity Disorder
(Peer reviewed; Journal article, 2012-04-23)Doublecortin and calmodulin like kinase 1 (DCLK1) is implicated in synaptic plasticity and neurodevelopment. Genetic variants in DCLK1 are associated with cognitive traits, specifically verbal memory and general cognition. ...