Blar i Faculty of Medicine på tittel
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Dissecting the hemagglutinin head and stalk-specific IgG antibody response in healthcare workers following pandemic H1N1 vaccination
(Peer reviewed; Journal article, 2016-07-28)Traditionally, neutralising antibodies that are directed to the major surface glycoprotein hemagglutinin (HA) head domain are measured as surrogate correlates of protection against influenza. In addition to neutralization, ... -
Dissecting the Role of AXL in Cancer Immune Escape and Resistance to Immune Checkpoint Inhibition
(Journal article; Peer reviewed, 2022)The development and implementation of Immune Checkpoint Inhibitors (ICI) in clinical oncology have significantly improved the survival of a subset of cancer patients with metastatic disease previously considered uniformly ... -
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
(Journal article; Peer reviewed, 2022)Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic ... -
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools
(Journal article; Peer reviewed, 2022)Migraine is three times more prevalent in people with bipolar disorder or depression. The relationship between schizophrenia and migraine is less certain although glutamatergic and serotonergic neurotransmission are ... -
Distance and utilisation of out-of-hours services in a Norwegian urban/rural district: an ecological study
(Peer reviewed; Journal article, 2013-06-17)Background: Long travel distances limit the utilisation of health services. We wanted to examine the relationship between the utilisation of a Norwegian out-of-hours service and the distance from the municipality population ... -
Distant metastasis dynamics following subsequent surgeries after primary breast cancer removal
(Peer reviewed; Journal article, 2019)Background: The aim of the research was to separate the distant metastasis (DM) enhancing effect due to breast tumour removal from that due to surgical manoeuvre by itself. Methods: DM dynamics following surgery for ... -
Distinct Mitochondrial Remodeling During Mesoderm Differentiation in a Human-Based Stem Cell Model
(Journal article; Peer reviewed, 2021-10-14)Given the considerable interest in using stem cells for modeling and treating disease, it is essential to understand what regulates self-renewal and differentiation. Remodeling of mitochondria and metabolism, with the shift ... -
Distinct multivariate brain morphological patterns and their added predictive value with cognitive and polygenic risk scores in mental disorders
(Peer reviewed; Journal article, 2017-06-09)The brain underpinnings of schizophrenia and bipolar disorders are multidimensional, reflecting complex pathological processes and causal pathways, requiring multivariate techniques to disentangle. Furthermore, little is ... -
Distinct pathophysiological pathways in women and men with heart failure
(Journal article; Peer reviewed, 2022)Aims: Clinical differences between women and men have been described in heart failure (HF). However, less is known about the underlying pathophysiological mechanisms. In this study, we compared multiple circulating biomarkers ... -
Distinct single cell signal transduction signatures in leukocyte subsets stimulated with khat extract, amphetamine-like cathinone, cathine or norephedrine
(Peer reviewed; Journal article, 2013-07-11)Background: Amphetamine and amphetamine derivatives are suggested to induce an immunosuppressive effect. However, knowledge of how amphetamines modulate intracellular signaling pathways in cells of the immune system is ... -
Distinct T and NK cell populations may serve as immune correlates of protection against symptomatic pandemic influenza A(H1N1) virus infection during pregnancy
(Peer reviewed; Journal article, 2017-11-16)Maternal influenza infection during pregnancy is associated with increased risk of morbidity and mortality. However, the link between the anti-influenza immune responses and health-related risks during infection is not ... -
Distinct T cell subsets in adipose tissue are associated with obesity
(Journal article; Peer reviewed, 2022)Adipose tissue inflammation is a driving factor for the development of obesity-associated metabolic disturbances, and a role of adipose tissue T cells in initiating the pro-inflammatory signaling is emerging. However, data ... -
Distinctions Between Self-Report and Performance-Based Measures of Physical Function in Older Patients Prior to Chemotherapy
(Journal article; Peer reviewed, 2021)Background: The maintenance of physical function (PF) is an extremely important outcome for older adults. Objective: The aims of this study were to, identify differences in subjective and objective measures of PF between ... -
Distributed computing and data storage in proteomics: many hands make light work, and a stronger memory
(Peer reviewed; Journal article, 2014-03)Modern day proteomics generates ever more complex data, causing the requirements on the storage and processing of such data to outgrow the capacity of most desktop computers. To cope with the increased computational demands, ... -
Distributing development assistance for health: Simulating the implications of 11 criteria
(Peer reviewed; Journal article, 2017-04)After years of unprecedented growth in development assistance for health (DAH), the DAH system is challenged on several fronts: by the economic downturn and stagnation of DAH, by the epidemiological transition and increase ... -
Distribution and Determinants of Serum Zinc, Copper, and Selenium Levels among Children under Five Years from Popokabaka, Democratic Republic of Congo: A Cross-Sectional Study
(Journal article; Peer reviewed, 2022)Information about essential trace elements among children in many African countries, including the Democratic Republic of Congo (DRC), is limited. We aimed to measure the distribution and determinants of serum zinc (Zn), ... -
Distribution of Plasmodium species and assessment of performance of diagnostic tools used during a malaria survey in Southern and Western Provinces of Zambia
(Peer reviewed; Journal article, 2019-04-11)Background: Zambia continues to make strides in reducing malaria burden through the use of proven malaria interventions and has recently pledged to eliminate malaria by 2021. Case management services have been scaled up ... -
Distribution of psychotropic drugs into lipoproteins
(Peer reviewed; Journal article, 2019)Aim: The aim of this pilot study was to investigate whether psychotropic drugs frequently analyzed in a routine therapeutic drug monitoring laboratory bind to low-density lipoproteins/very-low-density lipoproteins (LDL/VLDL) ... -
Distributional effects of payment for performance in the health sector. Examining effects on structural quality, performance outcomes and service utilisation in Tanzania
(Doctoral thesis, 2018-11-07)Introduction: Payment for performance (P4P) involves the allocation of financial incentives to health workers and/or facilities for reaching pre-defined performance targets or measures. P4P has been used in high-income ... -
Distributional impact of infectious disease interventions in the Ethiopian Essential Health Service Package: a modelling study
(Journal article; Peer reviewed, 2023)Objectives Reducing inequalities in health and financial risk are key goals on the path toward universal health coverage, particularly in low-income and middle-income countries. The design of the health benefit package ...