Blar i Faculty of Medicine på tittel
Viser treff 2231-2250 av 8752
-
Drivers of successful implementation of integrated care for multi-morbidity: Mechanisms identified in 17 case studies from 8 European countries
(Journal article; Peer reviewed, 2021)This paper provides a deeper understanding of the mechanisms underlying implementation strategies for integrated care. As part of the SELFIE project, 17 integrated care programmes addressing multi-morbidity from eight ... -
Drug adherence in patient group with Parkinson's disease
(Master thesis, 2018-06-29)Background Patients with Parkinson’s disease needs medicines administered frequently to manage their condition and maintain their quality of life. Poor medicine adherence may influence health negatively, and cause an ... -
Drug delivery in pancreatic cancer : Quantitative studies of gemcitabine and sonoporation in patients and cell line models
(Doctoral thesis, 2020-03-06)Background Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis due to late stage diagnosis and unresponsiveness to chemotherapies. A dense desmoplastic tumour stroma is considered to represent a barrier against ... -
Drug information in pregnancy. Attitudes and needs among pregnant women and physicians
(Doctoral thesis, 2013-10-25)Background: Drug use in pregnancy is common and both pregnant women and their physicians are in need of appropriate information for decision-making regarding drug therapy. However, uncertainty about the risks of drug use ... -
Drug prescribing quality for older patients. Explicit indicators and multidisciplinary medication reviews
(Doctoral thesis, 2012-03-16)This thesis is based on three published papers that illuminate different aspects of prescribing quality and drug use in older patients who receive home nursing services or live in nursing homes. Persons older than 65 years ... -
Drug seller adherence to clinical protocols with integrated management of malaria, pneumonia and diarrhoea at drug shops in Uganda
(Peer reviewed; Journal article, 2015-07-16)Background: Drug shops are usually the first source of care for febrile children in Uganda although the quality of care they provide is known to be poor. Within a larger quasi-experimental study introducing the WHO/UNICEF ... -
Drug shops in integrated community case management of malaria, pneumonia and diarrhoea in Uganda: Appropriateness of care and adherence to treatment guidelines
(Doctoral thesis, 2016-02-09)Introduction. Private drug shops are an important source of care for children in sub-Saharan Africa, with about half of sick children seeking care at this level. However, these drug shops receive minimal regulation and ... -
Drug treatment at the end of life: An epidemiologic study in nursing homes
(Peer reviewed; Journal article, 2014)Objective. To examine drug treatment in nursing home patients at the end of life, and identify predictors of palliative drug therapy. Design. A historical cohort study. Setting. Three urban nursing homes in Norway. Subjects. ... -
Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: Marked differences between various antipsychotic drugs
(Peer reviewed; Journal article, 2006-10-20)Background: The etiology of schizophrenia is unknown, but neurodevelopmental disturbances, myelin- and oligodendrocyte abnormalities and synaptic dysfunction have been suggested as pathophysiological factors in this severe ... -
Druggable genome in attention deficit/hyperactivity disorder and its co-morbid conditions. New avenues for treatment.
(Peer reviewed; Journal article, 2019)Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder with only symptomatic care available. Genome-wide association (GWA) studies can provide a starting point in the search for novel drug ... -
DrugPred_RNA—A Tool for Structure-Based Druggability Predictions for RNA Binding Sites
(Journal article; Peer reviewed, 2021)RNA is an emerging target for drug discovery. However, like for proteins, not all RNA binding sites are equally suited to be addressed with conventional drug-like ligands. To this end, we have developed the structure-based ... -
Drusenoid pigment epithelial detachment volume is associated with a decrease in best-corrected visual acuity and central retinal thickness: the Norwegian Pigment Epithelial Detachment Study (NORPED) report no. 1
(Journal article; Peer reviewed, 2020)Purpose To investigate the association of drusenoid pigment epithelial detachment (DPED) volume and change in best‐corrected visual acuity (BCVA) and central retinal thickness (CRT) during the growth phase of large ... -
The dual role of glioma exosomal microRNAs: glioma eliminates tumor suppressor miR-1298-5p via exosomes to promote immunosuppressive effects of MDSCs
(Journal article; Peer reviewed, 2022)Clear evidence shows that tumors could secrete microRNAs (miRNAs) via exosomes to modulate the tumor microenvironment (TME). However, the mechanisms sorting specific miRNAs into exosomes are still unclear. In order to study ... -
Duodenal administered seal oil for patients with subjective food hypersensitivity: an explorative open pilot study
(Peer reviewed; Journal article, 2010-12)Short-term duodenal administration of n-3 polyunsaturated fatty acid (PUFA)-rich seal oil may improve gastrointestinal complaints in patients with subjective food hypersensitivity, as well as joint pain in patients with ... -
Duodenal Chromogranin A Cell Density as a Biomarker for the Diagnosis of Irritable Bowel Syndrome
(Peer reviewed; Journal article, 2014-06-16)Background and Aim. Chromogranin A (CgA) is a common marker for endocrine cells. The density of duodenal CgA cells is reduced in patients with irritable bowel syndrome (IBS). Methods. The present study was undertaken to ... -
Durable immune responses after BNT162b2 vaccination in home-dwelling old adults
(Journal article; Peer reviewed, 2023)Objectives Elderly are an understudied, high-risk group vulnerable to severe COVID-19. We comprehensively analyzed the durability of humoral and cellular immune responses after BNT162b2 vaccination and SARS-CoV-2 infection ... -
Durable T-cellular and humoral responses in SARS-CoV-2 hospitalized and community patients
(Journal article; Peer reviewed, 2022)Background Neutralizing antibodies are important for protection against the pandemic SARS-CoV-2 virus, and long-term memory responses determine the risk of re-infection or boosting after vaccination. T-cellular responses ... -
Duration of elevated heart rate Is an important predictor of exercise-induced troponin elevation
(Journal article; Peer reviewed, 2020)Background The precise mechanisms causing cardiac troponin (cTn) increase after exercise remain to be determined. The aim of this study was to investigate the impact of heart rate (HR) on exercise‐induced cTn increase by ... -
Dust exposure and chronic respiratory symptoms among coffee curing workers in Kilimanjaro: a cross sectional study
(Peer reviewed; Journal article, 2011-11-24)Background: Coffee processing causes organic dust exposure which may lead to development of respiratory symptoms. Previous studies have mainly focused on workers involved in roasting coffee in importing countries. This ... -
Dust exposure and respiratory health among Tanzanian coffee factory workers
(Doctoral thesis, 2013-09-27)Introduction: Exposure to organic dust may cause detrimental effects to the respiratory system of exposed workers. Organic dust is commonly contaminated with microbes and their derivatives such as bacteria and endotoxin, ...