Blar i Faculty of Medicine på tittel
Viser treff 3030-3049 av 8751
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Expression Profiling of Major Histocompatibility and Natural Killer Complex Genes Reveals Candidates for Controlling Risk of Graft versus Host Disease
(Peer reviewed; Journal article, 2011-01-28)Background: The major histocompatibility complex (MHC) is the most important genomic region that contributes to the risk of graft versus host disease (GVHD) after haematopoietic stem cell transplantation. Matching of MHC ... -
Expression, Purification, and Small Molecule Binding to Cysteine Sulfinic Acid Decarboxylase
(Master thesis, 2023-06-01)Cysteine Sulfinic acid decarboxylase (CSAD) is a PLP-dependent enzyme involved in the biosynthesis of taurine. It converts cysteine sulfinic acid (CSA) into hypotaurine. Hypotaurine is later oxidized into taurine, one of ... -
EXT proteins: Role in heparan sulfate Assembly and in Tumor biology
(Doctoral thesis, 2018-08-24)The exostosin family of proteins is necessary for heparan sulfate biosynthesis. Heparan sulfate polysaccharide biosynthesis is one of several different forms of proteinglycosylation processes that take place in the Golgi ... -
Extended-spectrum β-lactamase producing Klebsiella pneumoniae. A neonatal intensive care unit outbreak, long-term colonization in children and plasmid characteristics
(Doctoral thesis, 2014-12-19)Background: The increasing level of antimicrobial resistance among clinical relevant bacteria, especially the increasing prevalence of extended-spectrum β-lactamase (ESBL) producing Enterobacteriaceae, is of great concern ... -
Extending contact screening to 50 metre around tuberculosis patients in urban Pakistan : Follow-up of a large Active Case-finding Project
(Doctoral thesis, 2023-03-10)Tuberkulose pasienter som ikke er diagnostisert er et stort helseproblem i samfunnet i Pakistan. I 2020 var det 52% av det antatte totale nye tilfeller som ikke var registrert i det nasjonale TB programmet (NTP) i Pakistan, ... -
Extending contact screening within a 50-m radius of an index tuberculosis patient using Xpert MTB/RIF in urban Pakistan: Did it impact treatment outcomes?
(Journal article; Peer reviewed, 2021)Background Pakistan implemented initiatives to detect tuberculosis (TB) patients through extended contact screening (ECS); it improved case detection but treatment outcomes need assessment. Objectives To compare ... -
Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes
(Journal article; Peer reviewed, 2021)Patients with bipolar disorder (BIP) have a high risk of cardiovascular disease (CVD), despite considerable individual variation. The mechanisms underlying comorbid CVD in BIP remain largely unknown. We investigated polygenic ... -
Extensor tendon release in tennis elbow: results and prognostic factors in 80 elbows
(Peer reviewed; Journal article, 2011-03-16)Purpose The objectives of this study were to evaluate the results in the outpatient treatment of recalcitrant lateral epicondylitis with release of the common extensor origin according to Hohmann and to determine any ... -
External Hydrocephalus as a Cause of Infant Subdural Hematoma: Epidemiological and Radiological Investigations of Infants Suspected of Being Abused
(Journal article; Peer reviewed, 2022)Background Acute subdural hematoma (ASDH) and chronic subdural hematoma (CSDH) in infants have been regarded as highly specific for abuse. Other causes of CSDH have not been investigated in a large population. Purpose The ... -
External inspections of healthcare organizations : A study of organizational and clinical effects of inspections on the management of sepsis in Norwegian hospitals
(Doctoral thesis, 2021-05-11)External inspections of healthcare organizations serve different purposes, one of which is to bring about quality improvements in the care offered to patients. Research has offered many different perspectives on how well ... -
An external quality assessment feasibility study; cross laboratory comparison of haemagglutination inhibition assay and microneutralization assay performance for seasonal influenza serology testing: A FLUCOP study
(Journal article; Peer reviewed, 2023)Introduction: External Quality Assessment (EQA) schemes are designed to provide a snapshot of laboratory proficiency, identifying issues and providing feedback to improve laboratory performance and inter-laboratory agreement ... -
External quality assessment of point-of-care International Normalized Ratio (INR) testing in Europe
(Peer reviewed; Journal article, 2011-09)Background: Point-of-care testing (POCT) of prothrombin time, expressed as International Normalized Ratio (INR), is widely used to monitor patients in oral anticoagulation treatment. Guidelines recommend that POCT users ... -
External Quality Assurance of Point-of-Care testing : Participant performance and commutability of the control material
(Doctoral thesis, 2021-09-03)The term point-of-care (POC) testing refers to laboratory tests performed near the patient, as opposed to a clinical laboratory setting. The aim of POC testing is to generate fast test results that facilitate accurate ... -
External validation of SAPS II score reported to the Norwegian Intensive Care and Pandemic Registry (NIPaR)
(Journal article; Peer reviewed, 2023)Background: Simplified Acute Physiology Score II (SAPS II) is a mortality prediction model widely used to compensate for differences between intensive care units (ICU) in benchmarking and research. Accuracy of SAPS II is ... -
External validation of the RISC, RISC-Malawi, and PERCH clinical prediction rules to identify risk of death in children hospitalized with pneumonia
(Journal article; Peer reviewed, 2021)Background: Existing scores to identify children at risk of hospitalized pneumonia-related mortality lack broad external validation. Our objective was to externally validate three such risk scores. Methods: We applied the ... -
The extostosin family: Proteins with many functions
(Peer reviewed; Journal article, 2014-04)Heparan sulfates are complex sulfated molecules found in abundance at cell surfaces and in the extracellular matrix. They bind to and influence the activity of a variety of molecules like growth factors, proteases and ... -
Extra-colonic cancers in Lynch Syndrome
(Doctoral thesis, 2010-11-12)Lynch Syndrome (LS) is the most common of the hereditary colorectal cancer (CRC) syndromes. It is caused by germ-line mutations in one of the four mismatch repair (MMR) genes MLHl, MSH2, MSH6 or PMS2. Mutations in one of ... -
Extra-intestinal complications following acute giardiasis
(Doctoral thesis, 2022-05-12)Background: Giardia lamblia is a common waterborne protozoan parasite worldwide. A large outbreak occurred in Bergen, Norway, in 2004. It was caused by heavy rainfall overloading the sewage system leading to contamination ... -
The extracellular bone marrow microenvironment — a proteomic comparison of constitutive protein release by in vitro cultured osteoblasts and mesenchymal stem cells
(Journal article; Peer reviewed, 2021)Mesenchymal stem cells (MSCs) and osteoblasts are bone marrow stromal cells that contribute to the formation of stem cell niches and support normal hematopoiesis, leukemogenesis and development of metastases from distant ... -
Extracellular DNA concentrations in various aetiologies of acute kidney injury
(Journal article; Peer reviewed, 2022)Extracellular DNA (ecDNA) in plasma is a non-specific biomarker of tissue damage. Urinary ecDNA, especially of mitochondrial origin, is a potential non-invasive biomarker of kidney damage. Despite prominent tissue damage, ...