Blar i Faculty of Medicine på tittel
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External quality assessment of point-of-care International Normalized Ratio (INR) testing in Europe
(Peer reviewed; Journal article, 2011-09)Background: Point-of-care testing (POCT) of prothrombin time, expressed as International Normalized Ratio (INR), is widely used to monitor patients in oral anticoagulation treatment. Guidelines recommend that POCT users ... -
External Quality Assurance of Point-of-Care testing : Participant performance and commutability of the control material
(Doctoral thesis, 2021-09-03)The term point-of-care (POC) testing refers to laboratory tests performed near the patient, as opposed to a clinical laboratory setting. The aim of POC testing is to generate fast test results that facilitate accurate ... -
External validation of SAPS II score reported to the Norwegian Intensive Care and Pandemic Registry (NIPaR)
(Journal article; Peer reviewed, 2023)Background: Simplified Acute Physiology Score II (SAPS II) is a mortality prediction model widely used to compensate for differences between intensive care units (ICU) in benchmarking and research. Accuracy of SAPS II is ... -
External validation of the RISC, RISC-Malawi, and PERCH clinical prediction rules to identify risk of death in children hospitalized with pneumonia
(Journal article; Peer reviewed, 2021)Background: Existing scores to identify children at risk of hospitalized pneumonia-related mortality lack broad external validation. Our objective was to externally validate three such risk scores. Methods: We applied the ... -
The extostosin family: Proteins with many functions
(Peer reviewed; Journal article, 2014-04)Heparan sulfates are complex sulfated molecules found in abundance at cell surfaces and in the extracellular matrix. They bind to and influence the activity of a variety of molecules like growth factors, proteases and ... -
Extra-colonic cancers in Lynch Syndrome
(Doctoral thesis, 2010-11-12)Lynch Syndrome (LS) is the most common of the hereditary colorectal cancer (CRC) syndromes. It is caused by germ-line mutations in one of the four mismatch repair (MMR) genes MLHl, MSH2, MSH6 or PMS2. Mutations in one of ... -
Extra-intestinal complications following acute giardiasis
(Doctoral thesis, 2022-05-12)Background: Giardia lamblia is a common waterborne protozoan parasite worldwide. A large outbreak occurred in Bergen, Norway, in 2004. It was caused by heavy rainfall overloading the sewage system leading to contamination ... -
The extracellular bone marrow microenvironment — a proteomic comparison of constitutive protein release by in vitro cultured osteoblasts and mesenchymal stem cells
(Journal article; Peer reviewed, 2021)Mesenchymal stem cells (MSCs) and osteoblasts are bone marrow stromal cells that contribute to the formation of stem cell niches and support normal hematopoiesis, leukemogenesis and development of metastases from distant ... -
Extracellular DNA concentrations in various aetiologies of acute kidney injury
(Journal article; Peer reviewed, 2022)Extracellular DNA (ecDNA) in plasma is a non-specific biomarker of tissue damage. Urinary ecDNA, especially of mitochondrial origin, is a potential non-invasive biomarker of kidney damage. Despite prominent tissue damage, ... -
Extracellular matrix remodelling pathway in peripheral blood mononuclear cells from severe COVID-19 patients: an explorative study
(Journal article; Peer reviewed, 2024)There is a reciprocal relationship between extracellular matrix (ECM) remodelling and inflammation that could be operating in the progression of severe COVID-19. To explore the immune-driven ECM remodelling in COVID-19, ... -
Extracellular Vesicles as Next-Generation Diagnostics and Advanced Therapy Medicinal Products
(Journal article; Peer reviewed, 2024-06-13)Extracellular vesicles (EVs) hold great promise for clinical application as new diagnostic and therapeutic modalities. This paper describes major GMP-based upstream and downstream manufacturing processes for EV large-scale ... -
Extracellular Vesicles Derived from Primed Mesenchymal Stromal Cells Loaded on Biphasic Calcium Phosphate Biomaterial Exhibit Enhanced Macrophage Polarization
(Journal article; Peer reviewed, 2022)Mesenchymal stromal cells (MSC) loaded on biphasic calcium phosphate biomaterial (MSC + BCP) have been used as an advanced therapy medicinal product to treat complex maxillofacial bone defects in patients. Further, MSC-derived ... -
Extrapulmonary tuberculosis in Pakistan- A nation-wide multicenter retrospective study
(Journal article; Peer reviewed, 2020)Background Pakistan is fifth among high burden countries for tuberculosis. A steady increase is seen in extrapulmonary tuberculosis (EPTB), which now accounts for 20% of all notified TB cases. There is very limited ... -
Extrapulmonary tuberculosis in Pakistan: Challenges in diagnosis and detection of drug resistance
(Doctoral thesis, 2023-11-02)Bakgrunn: Pakistan er blant de fem landene med høyest forekomst av tuberkulose (TB) og legemiddelresistent TB. Ekstrapulmonær TB (EPTB) utgjør 20% av alle registrerte TB-pasienter, men det er lite informasjon om ... -
Extrapulmonary tuberculosis in the HIV endemic setting in Tanzania: challenges with diagnosis, comorbidities, and association with mortality
(Doctoral thesis, 2025-01-16)Diagnostisering av ekstrapulmonal tuberkulose er utfordrende grunnet behovet for invasiv prøvetaking, at det er få bakterier til stede og diagnostiske tester med dårligere sensitivitet på annet prøvemateriale enn sputum. ... -
Extrasynaptic NMDA receptors on rod pathway amacrine cells: molecular composition, activation, and signaling
(Peer reviewed; Journal article, 2019)In the rod pathway of the mammalian retina, axon terminals of glutamatergic rod bipolar cells are presynaptic to AII and A17 amacrine cells in the inner plexiform layer. Recent evidence suggests that both amacrines express ... -
Eye discomfort, headache and back pain among Mayan Guatemalan women taking part in a randomised stove intervention
(Peer reviewed; Journal article, 2007)Background: Indoor air pollution (IAP) from combustion of biomass fuels represents a global health problem, estimated to cause 1.6 million premature deaths annually. Aims: RESPIRE (Randomised Exposure Study of Pollution ... -
F18-FDG-PET for recurrent differentiated thyroid cancer: a systematic meta-analysis
(Peer reviewed; Journal article, 2015-07-09)Background Positron emission tomography (PET) with fluor-18-deoxy-glucose (FDG) is widely used for diagnosing recurrent or metastatic disease in patients with differentiated thyroid cancer (DTC). Purpose To assess the ... -
Fabry disease model in Zebrafish : Studying molecular mechanisms of Fabry nephropathy in a Gb3-free environment
(Doctoral thesis, 2023-03-21)Bakgrunn: Fabry sykdom (FS) er en X-bundet lysosomal avleiringssykdom betinget i mutasjon i alfa-galactosidase genet (GLA). Enzymet alfa-galactosidase A (α-GAL) er ansvarlig for nedbryting av fettstoffet globotriaocylceramid ... -
Facet arthropathy evaluation: CT or MRI?
(Journal article; Peer reviewed, 2019)Objective To assess the reliability of lumbar facet arthropathy evaluation with computed tomography (CT) or magnetic resonance imaging (MRI) in patients with and without lumbar disc prosthesis and to estimate the reliability ...