Browsing Faculty of Medicine by Title
Now showing items 3365-3384 of 8740
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Gendered perceptions on infant feeding in Eastern Uganda: continued need for exclusive breastfeeding support
(Peer reviewed; Journal article, 2010-10-26)Background: In resource-poor settings, HIV positive mothers are recommended to choose between ‘Exclusive breastfeeding’ (EBF) or ‘Exclusive replacement feeding’ (ERF). Acceptability, Feasibility, Affordability, Sustainability ... -
Gene expression alterations in salivary gland epithelia of Sjögren’s syndrome patients are associated with clinical and histopathological manifestations
(Journal article; Peer reviewed, 2021)Sjögren’s syndrome (SS) is a complex autoimmune disease associated with lymphocytic infiltration and secretory dysfunction of salivary and lacrimal glands. Although the etiology of SS remains unclear, evidence suggests ... -
Gene Expression Analysis in gla-Mutant Zebrafish Reveals Enhanced Ca2+ Signaling Similar to Fabry Disease
(Journal article; Peer reviewed, 2022)Fabry disease (FD) is an X-linked inborn metabolic disorder due to partial or complete lysosomal α-galactosidase A deficiency. FD is characterized by progressive renal insufficiency and cardio- and cerebrovascular involvement. ... -
Gene expression in the rat brain: High similarity but unique differences between frontomedial-, temporal- and occipital cortex
(Peer reviewed; Journal article, 2011-01-26)Background: The six-layered neocortex of the mammalian brain may appear largely homologous, but is in reality a modular structure of anatomically and functionally distinct areas. However, global gene expression seems to ... -
Gene expression in tumor cells and stroma in dsRed 4T1 tumors in eGFP-expressing mice with and without enhanced oxygenation
(Peer reviewed; Journal article, 2012-01-17)Background The tumor microenvironment is pivotal in tumor progression. Thus, we aimed to develop a mammary tumor model to elucidate molecular characteristics in the stroma versus the tumor cell compartment by global gene ... -
Gene expression profile of oral squamous cell carcinomas from Sri Lankan betel quid users
(Peer reviewed; Journal article, 2007-11)Oral squamous cell carcinoma (OSCC) is one of the major health problems in Sri Lanka and the disease is associated with the habit of Betel Quid (BQ) chewing. Using 35k oligo microarrays, we analyzed the gene expression ... -
Gene expression profiles in rat brain disclose CNS signature genes and regional patterns of functional specialisation
(Peer reviewed; Journal article, 2007-04-04)Background: The mammalian brain is divided into distinct regions with structural and neurophysiological differences. As a result, gene expression is likely to vary between regions in relation to their cellular composition ... -
Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains
(Peer reviewed; Journal article, 2019-07-15)About 80% of colorectal cancers (CRCs) have chromosomal instability, which is an integral part of aggressive malignancy development, but the importance of specific copy number aberrations (CNAs) in modulating gene expression, ... -
Gene expression profiling of meningiomas: current status after a decade of microarray-based transcriptomic studies
(Peer reviewed; Journal article, 2011-01-14)Purpose This article provides a review of the transcriptomic expression profiling studies that have been performed on meningiomas so far. We discuss some future prospects and challenges ahead in the field of gene expression ... -
Gene expression response in peripheral blood cells of petroleum workers exposed to sub-ppm benzene levels
(Peer reviewed; Journal article, 2018-10-27)Altered gene expression in pathways relevant to leukaemogenesis, as well as reduced levels of circulating lymphocytes, have been reported in workers that were exposed to benzene concentrations below 1 ppm. In this study, ... -
Gene Methylation and Silencing of WIF1 Is a Frequent Genetic Abnormality in Mantle Cell Lymphoma
(Journal article; Peer reviewed, 2021)We have previously shown that the Wnt canonical pathway (WCP) is constitutively active in most cases of mantle cell lymphoma (MCL). Here, we aimed to elucidate the mechanisms underlying this biochemical deregulation. We ... -
A gene signature identifying CIN3 regression and cervical cancer survival
(Journal article; Peer reviewed, 2021-11-16)The purpose of this study was to establish a gene signature that may predict CIN3 regression and that may aid in selecting patients who may safely refrain from conization. Oncomine mRNA data including 398 immune-related ... -
Gene signatures and prognostic factors in endometrial cancer. A study with special focus on vascular invasion
(Doctoral thesis, 2011-04-15) -
Gene-Based Analysis of Regionally Enriched Cortical Genes in GWAS Data Sets of Cognitive Traits and Psychiatric Disorders
(Peer reviewed; Journal article, 2012-02-22)Background: Despite its estimated high heritability, the genetic architecture leading to differences in cognitive performance remains poorly understood. Different cortical regions play important roles in normal cognitive ... -
Gene-Environment Interactions in Attention-Deficit/Hyperactivity Disorder Symptom Dimensions: The Role of Unhealthy Food Habits
(Journal article; Peer reviewed, 2021)Background: Dietary habits were investigated as environmental risk factors for Attention-Deficit/Hyperactivity Disorder (ADHD). However, no previous studies explored the effects of dietary factors on modifying the role of ... -
Gene-methylation interactions: Discovering region-wise DNA methylation levels that modify SNP-associated disease risk
(Journal article; Peer reviewed, 2020)Background Current technology allows rapid assessment of DNA sequences and methylation levels at a single-site resolution for hundreds of thousands of sites in the human genome, in thousands of individuals simultaneously. ... -
General and orofacial symptoms associated with acute and long COVID in 80- and 90-year-old Swedish COVID-19 survivors
(Journal article; Peer reviewed, 2023)Objectives To describe acute and long COVID-19 symptoms among older elderly Swedes and to find predictive factors for the development symptoms associated with acute and long COVID. Material and methods A questionnaire ... -
General anxiety, depression, and physical health in relation to symptoms of heart-focused anxietya cross sectional study among patients living with the risk of serious arrhythmias and sudden cardiac death
(Peer reviewed; Journal article, 2011-11-14)Objective: To investigate the role of three distinct symptoms of heart-focused anxiety (cardio-protective avoidance, heart-focused attention, and fear about heart sensations) in relation to general anxiety, depression and ... -
General practice – a fertile lagoon in the ocean of medical knowledge
(Journal article; Peer reviewed, 2021)General practitioners (GPs) often find that linear, deductive knowledge does not provide a sufficient map for clinical management. But experience, accompanied by enduring familiarity with individual patients, may offer ... -
The general practitioner as lifestyle advisor. A focus group study exploring case story discussions
(Doctoral thesis, 2012-11-23)Background: GPs have a mandate from society to facilitate their patients to adopt a healthy lifestyle to reduce the burden of non-communicable diseases. GPs consider lifestyle counselling as an important but challenging ...