Browsing Faculty of Medicine by Title
Now showing items 5973-5992 of 9528
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Multi-omics profiling reveals dysregulated ribosome biogenesis and impaired cell proliferation following knockout of CDR2L
(Journal article; Peer reviewed, 2024)Background Cerebellar degeneration-related (CDR) proteins are associated with paraneoplastic cerebellar degeneration (PCD) – a rare, neurodegenerative disease caused by tumour-induced autoimmunity against neural antigens ... -
Multi-psychotropic drug prescription and the association to neuropsychiatric symptoms in three Norwegian nursing home cohorts between 2004 and 2011
(Peer reviewed; Journal article, 2016-06-01)Background Neuropsychiatric symptoms, such as affective symptoms, psychosis, agitation, and apathy are common among nursing home patients with and without dementia. Treatment with one or more psychotropic drug is often ... -
Multi-Wavelength Photobiomodulation Therapy Combined with Static Magnetic Field on Long-Term Pulmonary Complication after COVID-19: A Case Report
(Journal article; Peer reviewed, 2021)Introduction: Photobiomodulation therapy, alone (PBMT) or combined with a static magnetic field (PBMT-sMF), has been demonstrated to be effective in the regeneration of tissues, modulation of inflammatory processes, and ... -
A multicenter study on Leigh syndrome: disease course and predictors of survival
(Peer reviewed; Journal article, 2014-04-15)Background: Leigh syndrome is a progressive neurodegenerative disorder, associated with primary or secondary dysfunction of the mitochondrial oxidative phosphorylation. Despite the fact that Leigh syndrome is the most ... -
A multicomponent intervention to optimise nurseepatient communication in the intensive care unit: A mixed-methods acceptability and feasibility study
(Journal article; Peer reviewed, 2021)Background Mechanically ventilated patients in intensive care units may experience communication challenges owing to intubation, which affects nurse–patient communication. Several strategies may optimise communication, ... -
The multidimensional fatigue inventory (MFI-20): psychometrical testing in a Norwegian sample of inflammatory bowel disease (IBD) patients
(Journal article; Peer reviewed, 2022)OBJECTIVES To evaluate the psychometric properties of the Norwegian version of the multidimensional fatigue inventory (MFI-20) in patients with inflammatory bowel disease. METHODS Participants were recruited from nine ... -
Multidimensional tracking of phenotypes and organ involvement in a complete nationwide systemic sclerosis cohort
(Journal article; Peer reviewed, 2020)Objective SSc is a severe, heterogeneous multi-organ disease where population-based estimates on phenotypic spectrum, overall disease burden and societal impact are largely missing. Here the objective was to provide the ... -
Multidimensjonal stratifisert behandling av uspesifikke korsryggsmerter: en systematisk oversikt
(Master thesis, 2016-10-31)Studiedesign: Systematic review. Background: Non-specific low back pain (NSLBP) is a heterogeneous condition that has proven difficult to treat. To increase treatment effects stratified care is regarded as a promising ... -
Multidisciplinary approaches to identifying and managing global airways disease: Expert recommendations based on qualitative discussions
(Journal article; Peer reviewed, 2023)Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma frequently co-exist and share pathologic features. Taking a “global” treatment approach benefits diagnosis and treatment of both, but care is often ... -
Multidisciplinary intervention versus brief intervention in specialist healthcare. Attempting to improve outcomes for patients on sick leave with musculoskeletal pain
(Doctoral thesis, 2018-12-11)Background: Musculoskeletal pain (MSK), such as low back pain (LBP), neck pain and widespread pain, is among the most common health problems in industrial countries. Subsequently, MSK is associated with substantial healthcare ... -
Multifaceted intervention including Facebook-groups to improve guideline-adherence in ICU: A quasi-experimental interrupted time series study
(Journal article; Peer reviewed, 2021)Background: The impact of social media, with its speed, reach and accessibility, in interventions aimed to improve adherence to guidelines such as assessment of Pain, Agitation/Sedation and Delirium (PAD) in intensive care ... -
Multifasettert analyse av stabilitet og reologiske egenskaper i forbindelse med formulering av karbamidkremer
(Master thesis, 2023-06-06)Karbamidkrem har bred klinisk anvendelse innen dermatologi for behandling av tørr hud, kløe og atopisk eksem, takket være dens fuktighetsgivende og keratolytiske egenskaper. Kremformuleringer er imidlertid termodynamisk ... -
Multilevel analyses of related public health indicators: The European Surveillance of Congenital Anomalies (EUROCAT) Public Health Indicators
(Journal article; Peer reviewed, 2020)Background Public health organisations use public health indicators to guide health policy. Joint analysis of multiple public health indicators can provide a more comprehensive understanding of what they are intended to ... -
A multilevel, step-based model to evaluate progress in procedure efficiency for laparoscopic appendicectomy in surgical training: structured evaluation using 'ebb-and-flow' and 'string-of-pearls' concepts
(Journal article; Peer reviewed, 2022)Background Surgical training is aimed towards entrusted professional activity to obtain operative independence. Laparoscopic appendicectomy is performed early in training but except for simulators, real-life evaluation ... -
Multilocus analysis of SNP and metabolic data within a given pathway
(BMC Genomics 7(5), Peer reviewed; Journal article, 2006-01-13)Background: Complex traits, which are under the influence of multiple and possibly interacting genes, have become a subject of new statistical methodological research. One of the greatest challenges facing human geneticists ... -
Multimarker profiling identifies protective and harmful immune processes in heart failure: Findings from BIOSTAT-CHF
(Journal article; Peer reviewed, 2022)Aims The exploration of novel immunomodulatory interventions to improve outcome in heart failure (HF) is hampered by the complexity/redundancies of inflammatory pathways, which remain poorly understood. We thus aimed to ... -
Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden
(Journal article; Peer reviewed, 2021)Sequencing of cell-free DNA in the blood of cancer patients (liquid biopsy) provides attractive opportunities for early diagnosis, assessment of treatment response, and minimally invasive disease monitoring. To unlock ... -
Multimodal imaging of gliomas in the context of evolving cellular and molecular therapies
(Peer reviewed; Journal article, 2014-09-30)The vastmajority ofmalignant gliomas relapse after surgery and standard radio-chemotherapy. Novelmolecular and cellular therapies are thus being developed, targeting specific aspects of tumor growth.While histopathology ... -
Multimodal Imaging of Orthotopic Mouse Model of Endometrial Carcinoma
(Peer reviewed; Journal article, 2015-08-07)Background: Orthotopic endometrial cancer models provide a unique tool for studies of tumour growth and metastatic spread. Novel preclinical imaging methods also have the potential to quantify functional tumour characteristics ... -
Multimodal Imaging of Physiologic Changes Induced by Anti-Angiogenic Therapy in Glioblastoma
(Doctoral thesis, 2014-12-18)Glioblastoma (GBM) is the most frequent and malignant form of primary brain tumors. The standard of care for this disease consists in surgical resection, followed by radiotherapy and chemotherapy. Yet, the infiltrative ...