Browsing Faculty of Medicine by Title
Now showing items 7166-7185 of 9246
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A prospective study on the role of smoking, environmental tobacco smoke, indoor painting and living in old or new buildings on asthma, rhinitis and respiratory symptoms
(Journal article; Peer reviewed, 2021)We studied associations between tobacco smoke, home environment and respiratory health in a 10 year follow up of a cohort of 11,506 adults in Northern Europe. Multilevel logistic regression models were applied to estimate ... -
A prospective, active haemovigilance study with combined cohort analysis of 19 175 transfusions of platelet components prepared with amotosalen-UVA photochemical treatment
(Peer reviewed; Journal article, 2015-05-15)Background and Objectives: A photochemical treatment process (PCT) utilizing amotosalen and UVA light (INTERCEPT™ Blood System) has been developed for inactivation of viruses, bacteria, parasites and leucocytes that can ... -
Prospects and challenges in the development of universal influenza vaccines
(Journal article; Peer reviewed, 2020-07-06)Current influenza vaccines offer suboptimal protection and depend on annual reformulation and yearly administration. Vaccine technology has rapidly advanced during the last decade, facilitating development of next-generation ... -
Prosthetic rehabilitation of the edentulous. A randomized controlled trial comparing implant-retained mandibular overdentures and conventionally relined mandibular dentures
(Doctoral thesis, 2012-11-02)Purpose: To investigate variables associated with satisfaction and self-perceived oral health among complete denture wearers. Subsequently, to assess the effect of two treatment modalities on masticatory ability, diet, ... -
Prostitusjon, kriminalisering og endring. Hvordan forbud mot kjøp av seksuelle tjenester påvirker sosiale hjelpetiltak i Norge
(Master thesis, 2011-05)Background: Since January 1st 2009 the purchase of sexual services has been criminalized in Norway. The new law criminalizing the clients has been understood to impose a zerotolerance-strategy towards prostitution. So far, ... -
Proteasome‐mediated regulation of GATA2 expression and androgen receptor transcription in benign prostate epithelial cells
(Journal article; Peer reviewed, 2022)GATA2 has been shown to be an important transcription factor together with androgen receptor (AR) in prostate cancer cells. Less is known about GATA2 in benign prostate epithelial cells. We have investigated if GATA2 ... -
Protected sampling is preferable in bronchoscopic studies of the airway microbiome
(Journal article; Peer reviewed, 2017)The aim was to evaluate susceptibility of oropharyngeal contamination with various bronchoscopic sampling techniques. 67 patients with obstructive lung disease and 58 control subjects underwent bronchoscopy with ... -
Protecting essential health services in low-income and middle-income countries and humanitarian settings while responding to the COVID-19 pandemic
(Journal article; Peer reviewed, 2020)In health outcomes terms, the poorest countries stand to lose the most from these disruptions. In this paper, we make the case for a rational approach to public sector health spending and decision making during and in the ... -
Protein and transcriptional biomarker profiling may inform treatment strategies in lower respiratory tract infections by indicating bacterial–viral differentiation
(Journal article; Peer reviewed, 2024)Lower respiratory tract infections (LRTIs) remain a significant global cause of infectious disease-related mortality. Accurate discrimination between acute bacterial and viral LRTIs is crucial for optimal patient care, ... -
Protein expression profiling of plasma and lungs at different stages of metastatic development in a human triple negative breast cancer xenograft model.
(Peer reviewed; Journal article, 2019-05-01)The main objective of this study was to identify single proteins or protein networks that might be used as diagnostic biomarkers or for therapeutic purposes by evaluating the protein expression profiling of plasma and lungs ... -
A protein extract from chicken reduces plasma homocysteine in rats
(Peer reviewed; Journal article, 2015-06-04)The present study aimed to evaluate effects of a water-soluble protein fraction of chicken (CP), with a low methionine/glycine ratio, on plasma homocysteine and metabolites related to homocysteine metabolism. Male Wistar ... -
Protein intake in children and growth and risk of overweight or obesity: A systematic review and meta-analysis
(Journal article; Peer reviewed, 2022)Objectives: The aim of this study was to examine the evidence for an association between the dietary protein intake in children and the growth and risk of overweight or obesity up to 18 years of age in settings relevant ... -
Protein Post-Translational Modification Crosstalk in Acute Myeloid Leukemia Calls for Action
(Peer reviewed; Journal article, 2019)Background: Post-translational modification (PTM) crosstalk is a young research field. However, there is now evidence of the extraordinary characterization of the different proteoforms and their interactions in a biological ... -
Protein profiling reveals inter-individual protein homogeneity of arachnoid cyst fluid and high qualitative similarity to cerebrospinal fluid
(Peer reviewed; Journal article, 2011-05-20)Background: The mechanisms behind formation and filling of intracranial arachnoid cysts (AC) are poorly understood. The aim of this study was to evaluate AC fluid by proteomics to gain further knowledge about ACs. Two goals ... -
Protein target highlights in CASP15: Analysis of models by structure providers
(Journal article; Peer reviewed, 2023)We present an in-depth analysis of selected CASP15 targets, focusing on their biological and functional significance. The authors of the structures identify and discuss key protein features and evaluate how effectively ... -
Proteogenomic Analysis of Polymorphisms and Gene Annotation Divergences in Prokaryotes using a Clustered Mass Spectrometry-Friendly Database
(Peer reviewed; Journal article, 2011-01)Precise annotation of genes or open reading frames is still a difficult task that results in divergence even for data generated from the same genomic sequence. This has an impact in further proteomic studies, and also ... -
Proteogenomics in Microbiology: Taking the Right Turn at the Junction of Genomics and Proteomics
(Peer reviewed; Journal article, 2014-12)High-accuracy and high-throughput proteomic methods have completely changed the way we can identify and characterize proteins. MS-based proteomics can now provide a unique supplement to genomic data and add a new level of ... -
Proteoglycans contribute to the functional integrity of the glomerular endothelial cell surface layer and are regulated in diabetic kidney disease
(Journal article; Peer reviewed, 2021)All capillary endothelia, including those of the glomeruli, have a luminal cell surface layer (ESL) consisting of glycoproteins, glycolipids, proteoglycans (PGs) and glycosaminoglycans. Previous results have demonstrated ... -
Proteome and Phosphoproteome Changes Associated with Prognosis in Acute Myeloid Leukemia
(Journal article; Peer reviewed, 2020)Acute myeloid leukemia (AML) is a hematological cancer that mainly affects the elderly. Although complete remission (CR) is achieved for the majority of the patients after induction and consolidation therapies, nearly ... -
Proteomic analysis of formalin-fixed paraffin-embedded glomeruli suggests depletion of glomerular filtration barrier proteins in two-kidney one-clip hypertensive rats
(Peer reviewed; Journal article, 2014-08-16)Background It is well known that hypertension may cause glomerular damage, but the molecular mechanisms involved are still incompletely understood. Methods In the present study, we used formalin-fixed paraffin-embedded ...