Blar i Faculty of Medicine på tittel
Viser treff 10-29 av 8740
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21-Hydroxylase-Specific CD8+ T Cells in Autoimmune Addison’s Disease Are Restricted by HLA-A2 and HLA-C7 Molecules
(Journal article; Peer reviewed, 2021)Objectives: CD8+ T cells targeting 21-hydroxylase (21OH) are presumed to play a central role in the destruction of adrenocortical cells in autoimmune Addison’s disease (AAD). Earlier reports have suggested two immunodominant ... -
24-Month HIV-free survival among HIV-exposed Infants in Lesotho: the PEAWIL cohort study
(Journal article; Peer reviewed, 2020)Introduction Following the implementation of the provision of lifelong antiretroviral therapy to all HIV-positive pregnant or breastfeeding women for prevention of mother-to-child transmission (PMTCT) of HIV by the Kingdom ... -
25-hydroxy-vitamin D concentration is not affected by severe or non-severe pneumonia, or inflammation, in young children
(Peer reviewed; Journal article, 2017-01-17)Poor vitamin D status has been associated with increased risk and severity of respiratory tract infections. Whether or not inflammation and infection affects 25-hydroxy vitamin D (25(OH)D) concentration is controversial ... -
25-year results after anterior cruciate ligament reconstruction with the use of a patellar tendon autograft
(Doctoral thesis, 2022-06-17)Background: Only a few studies of ACL reconstruction with >20 years of follow-up exists. It is still a pause in the literature concerning the patient’s further sports participation and long-term subjective and objective ... -
2D and 3D U-Nets for skull stripping in a large and heterogeneous set of head MRI using fastai
(Journal article, 2020)Skull stripping in brain imaging is the removal of the parts of images corresponding to non-brain tissue. Fast and accurate skull stripping is a crucial step for numerous medical brain imaging applications, e.g. registration, ... -
A 3-D post-mortem model provides rationale for complications in gastrointestinal surgery : a post-mortem corrosion-cast model
(Doctoral thesis, 2007-06-08) -
3D dynamic culture of mesenchymal stem cells under fluid flow : Implications for bone regeneration
(Doctoral thesis, 2023-10-06)Skjebnen og veksten til mesenkymale stamceller (MSC) kan påvirkes av biologiske stimuli. I benvev regnes skjærspenning fra væske forårsaket av interstitiell væskestrøm som den primære mekaniske stimulien på celleplan, som ... -
3D Modelling of Brain Metastasis Microenvironment for Evaluation of Tumour-Stromal Interactions
(Master thesis, 2023-06-01)Brain metastases (BM) occur when cancer cells from the primary location spread to the brain through the bloodstream. BM affects approximately 20-40 % of cancer patients, with the majority originating from lung, breast, and ... -
3D-printed Synthetic Polymer Templates for Bone Tissue Engineering : Bulk Modifications and Osteoconduction Assessment
(Doctoral thesis, 2022-10-21)Syntetiske polymerbiomaterialer er enkle å bearbeide, biologisk inerte og brukes derfor i en rekke biomedisinske applikasjoner. Forskning har i lang tid fokusert på å øke biologiske aktivitet til slike materialers, og å ... -
A 4 year prospective longitudinal study of progression of dental erosion associated to lifestyle in 13-14 year-old Swedish adolescents
(Peer reviewed; Journal article, 2016-04)Objectives To evaluate the progression of dental erosion in 13–14 year-olds after 4 years, and its association with lifestyle and oral health. Methods 227 randomly selected 13–14 year-olds from a Public Dental Clinic, ... -
450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy
(Peer reviewed; Journal article, 2012-10)Background: Epigenetic modifications, such as DNA methylation, due to in utero exposures may play a critical role in early programming for childhood and adult illness. Maternal smoking is a major risk factor for multiple ... -
A 60-year follow-up of the incidence and prevalence of multiple sclerosis in Hordaland County, Western Norway
(Peer reviewed; Journal article, 2015-01-14)Objective: Investigate the incidence of multiple sclerosis during 1953–2013 and estimate the prevalence rate of MS on 1 January 2003 and 2013 in Hordaland County, Western Norway. Methods: All patients with onset of disease ... -
A pharmacokinetic study of NAD replenishment therapy using Nicotinamide Riboside
(Master thesis, 2023-05-22)Parkinson`s disease (PD) is a major cause of death and disability, and currently only symptomatic treatment is available. Nicotinamide adenine dinucleotide (NAD) is a crucial molecule for maintaining life and promoting ... -
A pharmacokinetic study of Nicotinamide Mononucleotide as a potential therapy for Parkinson's Disease
(Master thesis, 2023-05-22)Parkinson’s disease (PD) is a common age-related neurodegenerative disorder, with a rapidly increasing age-dependent prevalence. Current treatment offers some symptomatic relief but has no effect on disease progression. ... -
´A storehouse of mother´s unconditional love and nectar´- The role of the National Comprehensive Lactation Management Centre in strengthening feeding of premature infants in New Delhi, India
(Master thesis, 2021-12-15)Introduction: Providing human milk to sick- and premature infants is a lifesaving intervention that alone can reduce neonatal mortality. Studies have shown that donor human milk is the second-best alternative after mother’s ... -
Aberrant signaling of immune cells in Sjögren's syndrome patient subgroups upon interferon stimulation
(Journal article; Peer reviewed, 2022)Background: Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease, characterized by mononuclear cell infiltrates in the salivary and lacrimal glands, leading to glandular atrophy and dryness. Patient heterogeneity ... -
Ability in daily activities after early supported discharge models of stroke rehabilitation
(Peer reviewed; Journal article, 2015)More knowledge is needed about how different rehabilitation models in the municipality influence stroke survivors’ ability in activities of daily living (ADL). Objectives: To compare three models of outpatient rehabilitation; ... -
Ability of a lean-seafood diet to modulate lipid and glucose metabolism in healthy humans – a randomized controlled trial with a crossover design
(Doctoral thesis, 2016-01-08)Background: A Westernised lifestyle, which involves a high-energy diet and reduced physical activity, is indisputably linked to the pandemics of obesity and type 2 diabetes. Prevention of cardiovascular disease and type 2 ... -
The ability of the Ages and Stages Questionnaire (ASQ) to indicate motor difficulties in infants in primary care
(Journal article; Peer reviewed, 2022)Introduction Delayed achievement of motor milestones may be an early indicator of motor difficulties. Parent-reported questionnaires may serve as an efficient, low-cost screening to identify infants in need of further ...