Browsing Faculty of Medicine by Title
Now showing items 997-1016 of 9320
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Calprotectin (S100A8/A9) and S100A12 in inflammatory arthritis : clinical and epidemiological studies of rheumatoid and psoriatic arthritis
(Doctoral thesis, 2007-12-14)Rheumatoid- and psoriatic arthritis (RA and PsA) are the two most prevalent inflammatory joint diseases in Caucasian. Different biomarkers in peripheral blood may contribute in the diagnostic and prognostic process, as ... -
Calprotectin (S100A8/A9) has the strongest association with ultrasound-detected synovitis and predicts response to biologic treatment: results from a longitudinal study of patients with established rheumatoid arthritis
(Peer reviewed; Journal article, 2017-01-12)Background: Calprotectin (S100A8/A9 or MRP8/14) and S100A12 (leukocyte-derived proteins), interleukin 6 (IL-6) and vascular endothelial growth factor (VEGF) are markers of inflammation and angiogenesis. Ultrasound (US) is ... -
Calprotectin, a sensitive marker of inflammation, is robustly assessed in plasma from patients with early or established rheumatoid arthritis by use of different laboratory methods
(Journal article; Peer reviewed, 2023)Calprotectin (S100A8/S100A9, MRP8/MRP14) is a major leukocyte protein found to be more sensitive than C-Reactive Protein (CRP) and Erythrocyte Sedimentation Rate (ESR) as a marker of inflammation in patients with rheumatoid ... -
Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines
(Peer reviewed; Journal article, 2009-11-13)Background: An organic extract of the recreational herb khat (Catha edulis Forsk.) triggers cell death in various leukemia cell lines in vitro. The chemotherapeutics camptothecin, a plant alkaloid topoisomerase I inhibitor, ... -
Can 'early programming' be partly explained by smoking? Results from a prospective, population-based cohort study
(Peer reviewed; Journal article, 2015-01)Background: Numerous studies have focused the association between low birthweight and later disease. Our objective was to study the association between birthweight and later adult smoking and thereby explore a possible ... -
Can a structured electronic medical record with decision-making support improve nursing home quality? Healthcare administration through structured records
(Doctoral thesis, 2013-05-31)Background: Nursing homes face challenges in the coming years due to the increased number of elderly. A new law in force from Jan 2012 (“Samhandlingsreformen”) places more responsibilities on the counties running the nursing ... -
Can adults with cerebral palsy perform and beneft from ballistic strength training to improve walking outcomes? A mixed methods feasibility study
(Journal article; Peer reviewed, 2021)Background: Power bursts of hips and ankle plantar flexors are prerequisites to walking propulsion. However, these power bursts are reduced during gait for persons with cerebral palsy (CP) and mainly in the ankle plantar ... -
Can air pollution affect tear film stability? a cross-sectional study in the aftermath of an explosion accident
(Peer reviewed; Journal article, 2011-04-14)Background: After an explosion and fire in two tanks containing contaminated oil and sulphur products in a Norwegian industrial harbour in 2007, the surrounding area was polluted. This caused an intense smell, lasting until ... -
Can air pollution affect tear film stability? a cross-sectional study in the aftermath of an explosion accident
(Peer reviewed; Journal article, 2011-04-14)Background After an explosion and fire in two tanks containing contaminated oil and sulphur products in a Norwegian industrial harbour in 2007, the surrounding area was polluted. This caused an intense smell, lasting until ... -
Can an integrated intervention package including peer support increase the proportion of health facility births? A cluster randomised controlled trial in Northern Uganda
(Journal article; Peer reviewed, 2024)Objective: To assess the effect of an integrated intervention package compared with routine government health services on the frequency of health facility births. Setting: Three subcounties of Lira district in Northern ... -
Can bone apposition predict the retention force of a femoral stem? An experimental weight-bearing hip-implant model in goats
(Peer reviewed; Journal article, 2015-04-28)Background: The increasing incidence of prosthesis revision surgery in the Western world has led to an increased focus on the capacity for stem removal. We previously reported on a femoral stem implanted in goats with an ... -
Can clinical ethics committees be legitimate actors in bedside rationing?
(Peer reviewed; Journal article, 2019-12-19)Background Rationing and allocation decisions at the clinical level – bedside rationing – entail complex dilemmas that clinicians and managers often find difficult to handle. There is a lack of mechanisms and aids for ... -
Can Electronic Tools Help Improve Nursing Home Quality?
(Journal article, 2011)Background: Nursing homes face challenges in the coming years due to the increased number of elderly. Quality will be under pressure, expectations of the services will rise, and clinical complexity will grow. New strategies ... -
Can Geographically Targeted Vaccinations Be Ethically Justified? The Case of Norway During the COVID-19 Pandemic
(Journal article; Peer reviewed, 2023)This article discusses the fairness of geographically targeted vaccinations (GTVs). During the initial period of local and global vaccine scarcity, health authorities had to enact priority-setting strategies for mass ... -
Can insomnia in pregnancy predict postpartum depression? A longitudinal, population-based study
(Peer reviewed; Journal article, 2014-04-14)Background: Insomnia and depression are strongly interrelated. This study aimed to describe changes in sleep across childbirth, and to evaluate whether insomnia in pregnancy is a predictor of postpartum depression. Methods: ... -
Can medical algorithms be fair? Three ethical quandaries and one dilemma
(Journal article; Peer reviewed, 2022)Objective: To demonstrate what it takes to reconcile the idea of fairness in medical algorithms and machine learning (ML) with the broader discourse of fairness and health equality in health research. Method: The ... -
Can routine information from electronic patient records predict a future diagnosis of alcohol use disorder?
(Peer reviewed; Journal article, 2016)Objective: To explore whether information regarding potentially alcohol-related health incidents recorded in electronic patient records might aid in earlier identification of alcohol use disorders. Design: We extracted ... -
Can sexual health interventions make community-based health systems more responsive to adolescents? A realist informed study in rural Zambia
(Journal article; Peer reviewed, 2020)Introduction Community-based sexual reproductive interventions are key in attaining universal health coverage for all by 2030, yet adolescents in many countries still lack health services that are responsive to their ... -
Can spirometric norms be set using pre- or post- bronchodilator test results in older people?
(Peer reviewed; Journal article, 2012-11-16)Background: Chronic Obstructive Pulmonary Disease (COPD) is defined by post-bronchodilator spirometry. Data on “normal values” come predominantly from pre-bronchodilator spirometry. The effects of this on diagnosis are ... -
Can subjective well-being and body concern in adolescence predict prescribed medication in adulthood? Findings from the Nord-Trøndelag Health Study and the Norwegian Prescription Database
(Peer reviewed; Journal article, 2019)Aim: To examine whether subjective well-being (SW) and body concern among adolescents aged 15–19 years has an impact on adult health, measured by medications dispensed on average 18 years later. Methods: Data collected in ...