Browsing Faculty of Medicine by Title
Now showing items 7706-7725 of 9211
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S100 proteins in acute myeloid leukemia
(Peer reviewed; Journal article, 2018-12)The S100 protein family contains 20 functionally expressed members, which are commonly dysregulated in cancer. Their wide range of functions includes cell proliferation, cell differentiation, regulation of transcription ... -
S100A16 promotes differentiation and contributes to a less aggressive tumor phenotype in oral squamous cell carcinoma
(Peer reviewed; Journal article, 2015-09-09)Background: Altered expression of S100A16 has been reported in human cancers, but its biological role in tumorigenesis is not fully understood. This study aimed to investigate the clinical significance and functional role ... -
Safety and Clinical Efficacy of Mesenchymal Stem Cell Treatment in Traumatic Spinal Cord Injury, Multiple Sclerosis and Ischemic Stroke – A Systematic Review and Meta-Analysis
(Journal article; Peer reviewed, 2022-05-30)Background: Mesenchymal stem cells (MSCs) is an attractive candidate in regenerative research and clinical trials have assessed their therapeutic potential in different neurological conditions with disparate etiologies. ... -
Safety and efficacy of epithelium-on corneal collagen cross-linking using a multifactorial approach to achieve proper stromal riboflavin saturation
(Journal article; Peer reviewed, 2012)Purpose: To evaluate the efficacy and safety of epithelium-on corneal collagen cross-linking (CXL) using a multifactorial approach to achieve proper stromal riboflavin saturation. Methods: This non-randomized retrospective ... -
Safety and efficacy of faecal microbiota transplantation by Anaerobic Cultivated Human Intestinal Microbiome (ACHIM) in patients with systemic sclerosis: Study protocol for the randomised controlled phase II ReSScue trial
(Journal article; Peer reviewed, 2021)Introduction: In the multisystem inflammatory disorder systemic sclerosis (SSc), gastrointestinal tract (GIT) affliction is highly prevalent. There are no known disease modifying therapies and the negative impact is ... -
Safety and efficacy of pegunigalsidase alfa in patients with Fabry disease who were previously treated with agalsidase alfa: results from BRIDGE, a phase 3 open-label study
(Journal article; Peer reviewed, 2023)Background Pegunigalsidase alfa is a novel, PEGylated α-galactosidase-A enzyme-replacement therapy approved in the EU and US to treat patients with Fabry disease (FD). Objective/methods BRIDGE is a phase 3 open-label, ... -
Safety and efficacy of rituximab as first- and second line treatment in multiple sclerosis – A cohort study
(Journal article; Peer reviewed, 2021-01-31)Background Rituximab is increasingly used as off-label therapy in multiple sclerosis (MS). More data are needed on safety and efficacy of rituximab, particularly in cohorts of de novo patients and patients in early therapy ... -
The safety attitudes questionnaire - Ambulatory version: Psychometric properties of the Norwegian translated version for the primary care setting
(Peer reviewed; Journal article, 2014-04-29)Background: Patient safety culture is how leader and staff interaction, attitudes, routines and practices protect patients from adverse events in healthcare. The Safety Attitudes Questionnaire is the most widely used ... -
The safety attitudes questionnaire - ambulatory version: psychometric properties of the Norwegian translated version for the primary care setting
(Peer reviewed; Journal article, 2014-03-29)Background: Patient safety culture is how leader and staff interaction, attitudes, routines and practices protect patients from adverse events in healthcare. The Safety Attitudes Questionnaire is the most widely used ... -
The safety attitudes questionnaire – ambulatory version: psychometric properties of the Norwegian version for nursing homes
(Peer reviewed; Journal article, 2019)Background: Patient safety culture involves leader and staff interaction, routines, attitudes, practices and awareness that influence risks of adverse events in patient care. The Safety Attitudes Questionnaire (SAQ) is an ... -
Safety measures to prevent workplace violence in emergency primary care centres - a cross-sectional study
(Peer reviewed; Journal article, 2013-10-03)Background: Employees in emergency primary care centres (EPCC) have raised personal safety as an issue. Despite a high risk of experiencing workplace violence at EPCCs in Norway, knowledge regarding applied preventive ... -
Safety of breast feeding during rituximab treatment in multiple sclerosis
(Journal article; Peer reviewed, 2022)Background There are limited data on the safety of breast feeding during rituximab therapy. Our objective is to determine exposure from breast feeding and biological effects of rituximab in breastfed infants. Methods ... -
Safety of drug use in patients with a primary mitochondrial disease: An international Delphi-based consensus
(Journal article; Peer reviewed, 2020)Clinical guidance is often sought when prescribing drugs for patients with primary mitochondrial disease. Theoretical considerations concerning drug safety in patients with mitochondrial disease may lead to unnecessary ... -
Safety of hypoxic red blood cell administration in patients with transfusion-dependent hematological malignancies: An interim analysis
(Journal article; Peer reviewed, 2023)Anemia is a common symptom of hematological malignancies and red blood cell (RBC) transfusion is the primary supportive treatment, with many patients becoming transfusion dependent. Hemanext Inc. (Lexington, MA, United ... -
Safety profile of herbal medicines submitted for marketing authorization in Tanzania: a cross-sectional retrospective study
(Journal article; Peer reviewed, 2023)Background The popular use of herbal medicines necessitates national regulatory authorities to have efficient mechanisms for the control of these products including marketing authorization (MA) and safety follow-up. ... -
Safety, Immunogenicity, Efficacy and Effectiveness of Inactivated Influenza Vaccines in Healthy Pregnant Women and Children Under 5 Years: An Evidence-Based Clinical Review
(Journal article; Peer reviewed, 2021)Annual influenza vaccination is often recommended for pregnant women and young children to reduce the risk of severe influenza. However, most studies investigating the safety, immunogenicity, and efficacy or effectiveness ... -
Salivary Gland Ultrasonography in Sjögren’s Syndrome: A European Multicenter Reliability Exercise for the HarmonicSS Project
(Journal article, 2020)Objectives: Salivary gland ultrasonography (SGUS) is increasingly applied for the management of primary Sjögren's syndrome (pSS). This study aims to: (i) compare the reliability between two SGUS scores; (ii) test the ... -
Salivary glands of primary Sjögren’s syndrome patients express factors vital for plasma cell survival
(Peer reviewed; Journal article, 2011-01-07)Introduction: The presence of circulating Ro/SSA and La/SSB autoantibodies has become an important marker in the classification criteria for primary Sjögren’s syndrome (pSS). Plasma cells producing these autoantibodies are ... -
Salivary Oral Microbiome of Children With Juvenile Idiopathic Arthritis: A Norwegian Cross-Sectional Study
(Journal article; Peer reviewed, 2020)Background: The oral microbiota has been connected to the pathogenesis of rheumatoid arthritis through activation of mucosal immunity. The objective of this study was to characterize the salivary oral microbiome associated ...