Browsing Faculty of Medicine by Author "Haaland, Øystein Ariansen"
Now showing items 1-20 of 38
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Age, risk, and life expectancy in Norwegian intensive care: a registry-based population modelling study.
Lindemark, Frode; Haaland, Øystein Ariansen; Kvåle, Reidar; Flaatten, Hans; Johansson, Kjell Arne (Peer reviewed; Journal article, 2015-05-26)Background: Knowledge about the expected life years gained from intensive care unit (ICU) admission could inform priority-setting decisions across groups of ICU patients and across medical specialties. The aim of this study ... -
Analysis of Parent-of-Origin Effects on the X Chromosome in Asian and European Orofacial Cleft Triads Identifies Associations with DMD, FGF13, EGFL6, and Additional Loci at Xp22.2
Skare, Øivind; Lie, Rolv T.; Haaland, Øystein Ariansen; Gjerdevik, Miriam; Romanowska, Julia; Gjessing, Håkon K.; Jugessur, Astanand (Peer reviewed; Journal article, 2018-02-22)Background: Although both the mother's and father's alleles are present in the offspring, they may not operate at the same level. These parent-of-origin (PoO) effects have not yet been explored on the X chromosome, which ... -
Appraising Drugs Based on Cost-effectiveness and Severity of Disease in Norwegian Drug Coverage Decisions
Tranvåg, Eirik Joakim; Haaland, Øystein Ariansen; Robberstad, Bjarne; Norheim, Ole Frithjof (Journal article; Peer reviewed, 2022)Importance: Rising health care costs are a major health policy challenge globally. Norway has implemented a priority-setting system intended to balance cost-effectiveness and concerns for fair distribution, but little is ... -
A calibration study of SAPS II with Norwegian intensive care registry data
Haaland, Øystein Ariansen; Lindemark, Frode; Flaatten, Hans; Kvåle, Reidar; Johansson, Kjell Arne (Peer reviewed; Journal article, 2014-05-12)Background Mortality prediction is important in intensive care. The Simplified Acute Physiology Score (SAPS) II is a tool for predicting such mortality. However, the original SAPS II is poorly calibrated to current intensive ... -
Changes in life expectancy and disease burden in Norway, 1990–2019: an analysis of the Global Burden of Disease Study 2019
Clarsen, Benjamin Matthew; Nylenna, Magne; Klitkou, Søren Toksvig; Vollset, Stein Emil; Baravelli, Carl Michael; Bølling, Anette Kocbach; Aasvang, Gunn Marit; Sulo, Gerhard; Naghavi, Mohsen; Pasovic, Maja; Asaduzzaman, Muhammad; Bjørge, Tone; Eggen, Anne Elise; Eikemo, Terje Andreas; Ellingsen, Christian Lycke; Haaland, Øystein Ariansen; Hailu, Alemayehu; Hassan, Shoaib; Hay, Simon I.; Juliusson, Pétur Benedikt; Kisa, Adnan; Kisa, Sezer; Månsson, Johan; Yitayew, Teferi Mekonnen; Murray, Christopher J L; Norheim, Ole Frithjof; Ottersen, Trygve; Sagoe, Dominic; Sripada, Kam; Winkler, Andrea Sylvia; Knudsen, Ann Kristin Skrindo (Journal article; Peer reviewed, 2022)Background: Geographical differences in health outcomes are reported in many countries. Norway has led an active policy aiming for regional balance since the 1970s. Using data from the Global Burden of Disease Study (GBD) ... -
Costs and expected gain in lifetime health from intensive care versus general ward care of 30,712 individual patients: A distribution-weighted cost-effectiveness analysis
Lindemark, Frode; Haaland, Øystein Ariansen; Kvåle, Reidar; Flaatten, Hans; Norheim, Ole Frithjof; Johansson, Kjell Arne (Peer reviewed; Journal article, 2017-08-21)Background: Clinicians, hospital managers, policy makers, and researchers are concerned about high costs, increased demand, and variation in priorities in the intensive care unit (ICU). The objectives of this modelling ... -
Design efficiency in genetic association studies
Gjerdevik, Miriam; Gjessing, Håkon K.; Romanowska, Julia; Haaland, Øystein Ariansen; Jugessur, Astanand; Czajkowski, Nikolai Olavi; Lie, Rolv T. (Journal article; Peer reviewed, 2020)Selecting the best design for genetic association studies requires careful deliberation; different study designs can be used to scan for different genetic effects, and each design has its own set of strengths and limitations. ... -
Effect of kangaroo mother care initiated in community settings on financial risk protection of low-income households: a randomised controlled trial in Haryana, India
Choudhary, Tarun Shankar; Mazumder, Sarmila; Haaland, Øystein Ariansen; Taneja, Sunita; Bahl, Rajiv; Martines, Jose Carlos; Bahn, Maharaj Kishan; Norheim, Ole Frithjof; Sommerfelt, Halvor; Bhandari, Nita; Johansson, Kjell Arne (Journal article; Peer reviewed, 2022)Introduction Many families in low-income and middle-income countries have high out-of-pocket expenditures (OOPE) for healthcare, and some face impoverishment. We aimed to assess the effect of Kangaroo Mother Care initiated ... -
Effect of maternal sleep on embryonic development
Vietheer, Alexander; Kiserud, Torvid; Haaland, Øystein Ariansen; Lie, Rolv T.; Kessler, Jørg (Journal article; Peer reviewed, 2022)The concept of developmental origin of health and disease has ignited a search for mechanisms and health factors influencing normal intrauterine development. Sleep is a basic health factor with substantial individual ... -
The effect of WnT pathway modulators on human iPSC-derived pancreatic beta cell maturation
Vethe, Heidrun; Ghila, Luiza; Berle, Magnus; Hoareau, Laurence; Haaland, Øystein Ariansen; Scholz, Hanne; Paulo, Joao A.; Chera, Simona; Ræder, Helge (Peer reviewed; Journal article, 2019-05-08)Current published protocols for targeted differentiation of human stem cells toward pancreatic β-cells fail to deliver sufficiently mature cells with functional properties comparable to human islet β-cells. We aimed to ... -
Effectiveness and Safety of Low-Threshold Opioid-Agonist Treatment in Hard-To-Reach Populations with Opioid Dependence
Chalabianloo, Fatemeh; Ohldieck, Christian; Haaland, Øystein Ariansen; Fadnes, Lars T.; Johansson, Kjell Arne (Journal article; Peer reviewed, 2021)Objectives: Opioid-use disorder is related to premature death worldwide. Opioid-agonist treatment (OAT) is an effective treatment for opioid dependence. OAT delivery platforms may influence treatment access and outcomes, ... -
Estimating health adjusted age at death (HAAD)
Johansson, Kjell Arne; Økland, Jan-Magnus; Skaftun, Eirin Krüger; Bukhman, Gene; Norheim, Ole Frithjof; Coates, Matthew M.; Haaland, Øystein Ariansen (Journal article; Peer reviewed, 2020-07-14)Objectives: At any point in time, a person’s lifetime health is the number of healthy life years they are expected to experience during their lifetime. In this article we propose an equity-relevant health metric, Health ... -
Estimating impact of food choices on life expectancy: A modeling study
Fadnes, Lars T.; Økland, Jan-Magnus; Haaland, Øystein Ariansen; Johansson, Kjell Arne (Journal article; Peer reviewed, 2022)Background Interpreting and utilizing the findings of nutritional research can be challenging to clinicians, policy makers, and even researchers. To make better decisions about diet, innovative methods that integrate best ... -
Financial hardship associated with catastrophic out-of-pocket spending tied to primary care services in low- and lower-middle-income countries: findings from a modeling study
Bolongaita, Sarah Ann; Lee, Yeeun; Johansson, Kjell Arne; Haaland, Øystein Ariansen; Tolla, Mieraf Taddesse; Lee, Jongwook; Verguet, Stéphane (Journal article; Peer reviewed, 2023)Background Financial risk protection (FRP) is a key component of universal health coverage (UHC): all individuals must be able to obtain the health services they need without experiencing financial hardship. In many ... -
A first-level customization study of SAPS II with Norwegian Intensive Care and Pandemic Registry (NIPaR) data
Bruserud, Øyvind; Haaland, Øystein Ariansen; Kvåle, Reidar; Buanes, Eirik Alnes (Journal article; Peer reviewed, 2023)Background: Severity scores and mortality prediction models (MPMs) are important tools for benchmarking and stratification in the intensive care unit (ICU) and need to be regularly updated using data from a local and ... -
A flexible formula for incorporating distributive concerns into cost-effectiveness analyses: Priority weights
Haaland, Øystein Ariansen; Lindemark, Frode; Johansson, Kjell Arne (Peer reviewed; Journal article, 2019-10-10)Background Cost effectiveness analyses (CEAs) are widely used to evaluate the opportunity cost of health care investments. However, few functions that take equity concerns into account are available for such CEA methods, ... -
Frailty and survival in elderly intensive care patients in Norway
Andersen, Finn Husøy; Haaland, Øystein Ariansen; Klepstad, Pål; Flaatten, Hans (Journal article; Peer reviewed, 2021)Background Today, 10%-15% of Norwegian intensive care patients are ≥80 years. This proportion will increase significantly over the next 20 years, but it is unlikely that resources for intensive care increase correspondingly. ... -
Gene-methylation interactions: Discovering region-wise DNA methylation levels that modify SNP-associated disease risk
Romanowska, Julia; Haaland, Øystein Ariansen; Jugessur, Astanand; Gjerdevik, Miriam; Xu, Zongli; Taylor, Jack A.; Wilcox, Allen J; Jonassen, Inge; Lie, Rolv T.; Gjessing, Håkon K. (Journal article; Peer reviewed, 2020)Background Current technology allows rapid assessment of DNA sequences and methylation levels at a single-site resolution for hundreds of thousands of sites in the human genome, in thousands of individuals simultaneously. ... -
Genome-wide analysis of parent-of-origin interaction effects with environmental exposure (PoOxE): An application to European and Asian cleft palate trios
Haaland, Øystein Ariansen; Jugessur, Astanand; Gjerdevik, Miriam; Romanowska, Julia; Shi, Min; Beaty, Terri H.; Marazita, Mary L.; Murray, Jeffrey C.; Wilcox, Allen J.; Lie, Rolv T.; Gjessing, Håkon K. (Peer reviewed; Journal article, 2017-09-12)Cleft palate only is a common birth defect with high heritability. Only a small fraction of this heritability is explained by the genetic variants identified so far, underscoring the need to investigate other disease ... -
A genome-wide scan of cleft lip triads identifies parent-of-origin interaction effects between ANK3 and maternal smoking, and between ARHGEF10 and alcohol consumption
Haaland, Øystein Ariansen; Romanowska, Julia; Gjerdevik, Miriam; Lie, Rolv T.; Gjessing, Håkon K.; Jugessur, Astanand (Journal article; Peer reviewed, 2019-06-24)Background: Although both genetic and environmental factors have been reported to influence the risk of isolated cleft lip with or without cleft palate (CL/P), the exact mechanisms behind CL/P are still largely unaccounted ...