Browsing Faculty of Medicine by Journals "Diabetologia"

Now showing items 1-7 of 7

    • Associations between plasma kynurenines and cognitive function in individuals with normal glucose metabolism, prediabetes and type 2 diabetes: the Maastricht Study 

      Bakker, Lieke; Ramakers, Inez H. G. B.; van Boxtel, Martin P. J.; Schram, Miranda T.; Stehouwer, Coen D.A.; Van Der Kallen, Carla J.; Dagnelie, Pieter; Van Greevenbroek, Marleen M.J.; Wesselius, Anke; Midttun, Øivind; Ueland, Per M.; Verhey, Frans; Eussen, Simone; Köhler, Sebastian (Journal article; Peer reviewed, 2021)
      Aims/hypothesis Studies investigating associations between kynurenines and cognitive function have generally been small, restricted to clinical samples or have found inconsistent results, and associations in the general ...

    • Ceramide stearic to palmitic acid ratio predicts incident diabetes 

      Hilvo, Mika; Salonurmi, Tuire; Havulinna, Aki S.; Kauhanen, Dimple; Pedersen, Eva Ringdal; Tell, Grethe S.; Meyer, Klaus; Teeriniemi, Anna-Maria; Laatikainen, Tiina; Jousilahti, Pekka; Savolainen, Markku J.; Nygård, Ottar; Salomaa, Veikko; Laaksonen, Reijo (Peer reviewed; Journal article, 2018-03-15)
      Aims/hypothesis Ceramide lipids have a role in the development of insulin resistance, diabetes and risk of cardiovascular disease. Here we investigated four ceramides and their ratios to find the best predictors of incident ...

    • Characterisation of HNF1A variants in paediatric diabetes in Norway using functional and clinical investigations to unmask phenotype and monogenic diabetes 

      Svalastoga, Pernille; Kaci, Alba; Molnes, Janne; Solheim, Marie Holm; Johansson, Bente Berg; Krogvold, Lars; Skrivarhaug, Torild; Valen, Eivind; Johansson, Stefan; Molven, Anders; Sagen, Jørn Vegard; Søfteland, Eirik; Bjørkhaug, Lise; Tjora, Erling; Aukrust, Ingvild; Njølstad, Pål Rasmus (Journal article; Peer reviewed, 2023)
      Aims/hypothesis Correctly diagnosing MODY is important, as individuals with this diagnosis can discontinue insulin injections; however, many people are misdiagnosed. We aimed to develop a robust approach for determining ...

    • The contribution of functional HNF1A variants and polygenic susceptibility to risk of type 2 diabetes in ancestrally diverse populations 

      Stalbow, Lauren; Preuss, Michael H.; Smit, Roelof A.J.; Chami, Nathalie; Bjørkhaug, Lise; Aukrust, Ingvild; Gloyn, Anna L; Loos, Ruth J.F. (Journal article; Peer reviewed, 2023)
      Aims/hypothesis: We examined the contribution of rare HNF1A variants to type 2 diabetes risk and age of diagnosis, and the extent to which their impact is affected by overall genetic susceptibility, across three ancestry ...

    • Genetics of diabetes-associated microvascular complications 

      Lyssenko, Valeriya; Vaag, Allan (Journal article; Peer reviewed, 2023)
      Diabetes is associated with excess morbidity and mortality due to both micro- and macrovascular complications, as well as a range of non-classical comorbidities. Diabetes-associated microvascular complications are those ...

    • No association between long-chain n-3 fatty acid intake during pregnancy and risk of type 1 diabetes in offspring in two large Scandinavian pregnancy cohorts 

      Lund-Blix, Nicolai Andre; Bjerregaard, Anne A.; Tapia, German; Størdal, Ketil; Brantsæter, Anne Lise; Strøm, Marin; Halldorsson, Thorhallur I.; Granstrøm, Charlotta; Svensson, Jannet; Joner, Geir; Skrivarhaug, Torild; Njølstad, Pål Rasmus; Olsen, Sjurdur F.; Stene, Lars Christian Mørch (Journal article; Peer reviewed, 2024)
      Aims/hypothesis The aim of this study was to investigate whether higher dietary intake of marine n-3 fatty acids during pregnancy is associated with a lower risk of type 1 diabetes in children. Methods The Danish ...

    • Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study 

      Slieker, Roderick C.; Donnelly, Louise A.; Fitipaldi, Hugo; Bouland, Gerard A.; Giordano, Giuseppe N.; Åkerlund, Mikael; Gerl, Mathias J.; Ahlqvist, Emma; Ali, Ashfaq; Dragan, Iulian; Festa, Andreas; Hansen, Michael K.; Mansour Aly, Dina; Kim, Min; Kuznetsov, Dmitry; Mehl, Florence; Klose, Christian; Simons, Kai; Pavo, Imre; Pullen, Timothy J.; Suvitaival, Tommi; Wretlind, Asger; Rossing, Peter; Lyssenko, Valeriya; Legido-Quigley, Cristina; Groop, L; Thorens, Bernard; Franks, Paul W; Ibberson, Mark; Rutter, Guy A.; Beulens, Joline W.J.; ‘t Hart, Leen M.; Pearson, Ewan R. (Journal article; Peer reviewed, 2021)
      Aims/hypothesis: Five clusters based on clinical characteristics have been suggested as diabetes subtypes: one autoimmune and four subtypes of type 2 diabetes. In the current study we replicate and cross-validate these ...