• Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations 

      Bergland, Ola Undrum; Halvorsen, Lene Vernås; Søraas, Camilla Lund; Hjørnholm, Ulla; Kjær, Vibeke Norheim; Rognstad, Stine; Brobak, Karl Marius; Aune, Arleen; Olsen, Eirik; Fauchald, Ylva; Heimark, Sondre; Thorstensen, Christian W; Liestøl, Knut; Solbu, Marit Dahl; Gerdts, Eva; Mo, Rune; Rostrup, Morten; Kjeldsen, Sverre; Høieggen, Aud; Opdal, Mimi Stokke; Fadl Elmula, Fadl Elmula M. (Journal article; Peer reviewed, 2021)
      Nonadherence to drugs is a challenge in hypertension treatment. We aimed to assess the prevalence of nonadherence by serum drug concentrations compared with 2 indirect methods and relate to the prescribed drug regimens in ...
    • Heart failure in women with hypertensive disorders of pregnancy: Insights from the cardiovascular disease in Norway project 

      Honigberg, Michael C.; Riise, Hilde Kristin Refvik; Daltveit, Anne Kjersti; Tell, Grethe S.; Sulo, Gerhard; Igland, Jannicke; Klungsøyr, Kari; Scott, Nandita S.; Wood, Malissa J.; Natarajan, Pradeep; Rich-Edwards, Janet W. (Journal article; Peer reviewed, 2020)
      Hypertensive disorders of pregnancy (HDP) have been associated with heart failure (HF). It is unknown whether concurrent pregnancy complications (small-for-gestational-age or preterm delivery) or recurrent HDP modify ...
    • High-salt diet causes osmotic gradients and hyperosmolality in skin without affecting interstitial fluid and lymph 

      Nikpey Esfahlan, Elham; Karlsen, Tine Veronica; Rakova, Natalia; Titze, Jens M.; Tenstad, Olav; Wiig, Helge (Peer reviewed; Journal article, 2017-04)
      The common notion is that the body Na+ is maintained within narrow limits for fluid and blood pressure homeostasis. Several studies have, however, shown that considerable amounts of Na+ can be retained or removed from the ...
    • Metabolomics identifies placental dysfunction and confirms Flt-1 (FMS-like tyrosine kinase receptor 1) biomarker specificity 

      Austdal, Marie; Silva, Gabriela; Bowe, Sophie; Thomsen, Liv Cecilie Vestrheim; Tangerås, Line Haugstad; Bjørge, Line; Bathen, Tone Frost; Iversen, Ann-Charlotte (Journal article; Peer reviewed, 2019)
      Clinical end-stage parameters define the pregnancy disorders preeclampsia and fetal growth restriction while classification of the underlying placental dysfunction is missing and urgently needed. Flt-1 (FMS-like tyrosine ...
    • Prevention of Hypertension and Organ Damage in 2-Kidney, 1-Clip Rats by Tetradecylthioacetic Acid 

      Gudbrandsen, Oddrun Anita; Hultström, Michael; Leh, Sabine Maria; Bivol, Liliana Monica; Vågnes, Øyvind; Berge, Rolf Kristian; Iversen, Bjarne M. (Peer reviewed; Journal article, 2006-07-17)
      Dietary lipids are reported to affect the blood pressure in both humans and experimental animal models with hypertension. In the present study, 2-kidney, 1-clip (2K1C) hypertensive rats were treated with the modified fatty ...