Browsing Department of Biomedicine by Title

Now showing items 772-773 of 773

    • XAB2 promotes Ku eviction from single-ended DNA double-strand breaks independently of the ATM kinase 

      Sharma, Abhishek; Erasimus, Hélène; Pinto, Lia; Caron, Marie-Christine; Gopaul, Diyavarshini; Peterlini, Thibault; Neumann, Katrin; Nazarov, Petr V.; Fritah, Sabrina; Klink, Barbara; Herold-Mende, Christel C.; Niclou, Simone Pierrette; Pasero, Philippe; Calsou, Patrick; Masson, Jean-Yves; Britton, Sébastien; Van Dyck, Eric (Journal article; Peer reviewed, 2021)
      Replication-associated single-ended DNA double-strand breaks (seDSBs) are repaired predominantly through RAD51-mediated homologous recombination (HR). Removal of the non-homologous end-joining (NHEJ) factor Ku from resected ...

    • α11β1 integrin is induced in a subset of cancer- associated fibroblasts in desmoplastic tumor stroma and mediates in vitro cell migration 

      Zeltz, Cedric; Alam, Jahedul; Liu, Hengshuo; Erusappan, Pugazendhi M; Hoschuetzky, Heinz; Molven, Anders; Parajuli, Himalaya; Cukierman, Edna; Costea, Daniela Elena; Lu, Ning; Gullberg, Donald (Peer reviewed; Journal article, 2019-06-01)
      Integrin α11β1 is a collagen receptor that has been reported to be overexpressed in the stroma of non-small cell lung cancer (NSCLC) and of head and neck squamous cell carcinoma (HNSCC). In the current study, we further ...