Blar i Department of Biomedicine på tittel
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The Arc of synaptic memory
(Peer reviewed; Journal article, 2010)The immediate early gene Arc is emerging as a versatile, Wnely tuned system capable of coupling changes in neuronal activity patterns to synaptic plasticity, thereby optimizing information storage in the nervous system. ... -
Arc protein-protein interactions in long-term potentiation in the rat dentate gyrus in vivo
(Master thesis, 2014-06-02)Synaptic plasticity is the ability of neuronal synapses to change in strength over time, and is considered to be a foundation for learning and memory. Long-term potentiation (LTP) is a widely studied form of synaptic ... -
Aromatic Amino Acid Hydroxylases as Off-Targets of Histone Deacetylase Inhibitors
(Journal article; Peer reviewed, 2024)The aromatic amino acid hydroxylases (AAAHs) phenylalanine hydroxylase, tyrosine hydroxylase, and tryptophan hydroxylases 1 and 2 are structurally related enzymes that contain an active site iron atom and depend on ... -
Arsenic exposure and developmental neurotoxicity: An evaluation of biomarkers of effect.
(Master thesis, 2022-08-01) -
Assembly and Cellular Exit of Coronaviruses: Hijacking an Unconventional Secretory Pathway from the Pre-Golgi Intermediate Compartment via the Golgi Ribbon to the Extracellular Space
(Journal article; Peer reviewed, 2021)Coronaviruses (CoVs) assemble by budding into the lumen of the intermediate compartment (IC) at the endoplasmic reticulum (ER)-Golgi interface. However, why CoVs have chosen the IC as their intracellular site of assembly ... -
Assessing N-terminal acetylation status of cellular proteins via an antibody specific for acetylated methionine
(Journal article; Peer reviewed, 2024)N-terminal acetylation is being recognized as a factor affecting protein lifetime and proteostasis. It is a modification where an acetyl group is added to the N-terminus of proteins, and this occurs in 80 % of the human ... -
Assessment of Image Quality of a PET/CT scanner for a Standarized Image situation Using a NEMA Body Phantom. “The impact of Different Image Reconstruction Parameters on Image quality”
(Master thesis, 2013-09-01)Radiologists and medical practitioners are working daily with images from integrated Positron Emission Tomography/ Computed Tomography (PET/CT) scanners in order to detect potentially lethal diseases. It is thus very ... -
Association between the number of CAG repeats in polymerase gamma and Parkinson disease in the Norwegian population
(Master thesis, 2012-06-01)Parkinson disease (PD) is a common neurodegenerative movement disorder that increases in prevalence with age. It is characterized clinically by resting tremor, rigidity, bradykinesia, and failing balance, and is due to the ... -
Associations between attention-deficit/hyperactivity disorder and autoimmune diseases are modified by sex: a population-based cross-sectional study
(Peer reviewed; Journal article, 2018-05)Several studies have demonstrated associations between neuropsychiatric disorders, such as attention-deficit/hyperactivity disorder (ADHD), and the immune system, including autoimmune diseases. Since ADHD and many autoimmune ... -
Atomic view into plasmodium actin polymerization, ATP hydrolysis, and fragmentation
(Peer reviewed; Journal article, 2019)Plasmodium actins form very short filaments and have a noncanonical link between ATP hydrolysis and polymerization. Long filaments are detrimental to the parasites, but the structural factors constraining Plasmodium ... -
Attention Network Test in adults with ADHD - the impact of affective fluctuations
(Peer reviewed; Journal article, 2011-07-27)Background: The Attention Network Test (ANT) generates measures of different aspects of attention/executive function. In the present study we investigated whether adults with ADHD performed different from controls on ... -
Attention-deficit/hyperactivity disorder and smoking habits in pregnant women
(Journal article; Peer reviewed, 2020)Background Attention-deficit/hyperactivity disorder (ADHD) has been associated with an increased risk of tobacco smoking, and more difficulties with smoking cessation compared to non-ADHD individuals. Women with ADHD may ... -
Attention-Deficit/Hyperactivity Disorder in adults. Clinical characteristics and pre- and perinatal risk factors
(Doctoral thesis, 2011-01-28)Attention-deficit/hyperactivity disorder (ADHD) is currently a prevalent diagnosis in child psychiatry, typically affecting 2-5 % of school-aged children world-wide. The recent and increasing awareness that ADHD may persist ... -
Attention-deficit/hyperactivity disorder symptoms and dietary habits in adulthood: A large population-based twin study in Sweden
(Journal article; Peer reviewed, 2020)Associations between adult attention-deficit/hyperactivity disorder (ADHD) symptoms and dietary habits have not been well established and the underlying mechanisms remain unclear. We explored these associations using a ... -
Attention-deficit/hyperactivity disorder; sex differences in psychiatric comorbidity and transgenerational recurrence risks : A population-based study using Norwegian registry data
(Doctoral thesis, 2020-02-07)Background: Attention-deficit/hyperactivity disorder (ADHD) is a heterogeneous, multifactorial and life-spanning neurodevelopmental disorder for which the underlying mechanisms and causes are not fully understood. Psychiatric ... -
Autoimmune Addison's Disease and DNA Methylation. Identification of Differentially Methylated Regions and Development of Methylation Specific PCR for Selected Genes
(Master thesis, 2012-07-01)Autoimmune Addison's Disease (AAD) is a classical organ-specific autoimmune disease (AID) that is characterized by autoreactivity towards the adrenal cortex, leading to insufficient production of steroid hormones and death ... -
Automated Quantification and Integrative Analysis of 2D and 3D Mitochondrial Shape and Network Properties
(Peer reviewed; Journal article, 2014-07-02)Mitochondrial morphology and function are coupled in healthy cells, during pathological conditions and (adaptation to) endogenous and exogenous stress. In this sense mitochondrial shape can range from small globular ... -
Automated splitting into batches for observational biomedical studies with sequential processing
(Journal article; Peer reviewed, 2022)Experimental design usually focuses on the setting where treatments and/or other aspects of interest can be manipulated. However, in observational biomedical studies with sequential processing, the set of available samples ... -
AXL expression reflects tumor-immune cell dynamics impacting outcome in non-small cell lung cancer patients treated with immune checkpoint inhibitor monotherapy
(Journal article; Peer reviewed, 2024-08-21)Introduction: AXL receptor expression is proposed to confer immune-checkpoint inhibitor (ICI)-resistance in non-small cell lung cancer (NSCLC) patients. We sought to interrogate AXL expression in conjunction with mutational ...