Blar i Department of Biomedicine på forfatter "Karppinen, Sanna-Maria"

Viser treff 1-3 av 3

    • Lack of collagen XVIII leads to lipodystrophy and perturbs hepatic glucose and lipid homeostasis 

      Petäistö, Tiina; Vicente, David; Mäkelä, Kari A; Finnilä, Mikko A; Miinalainen, Ilkka; Koivunen, Jarkko; Izzi, Valerio; Aikio, Mari; Karppinen, Sanna-Maria; Davarajan, Raman; Thevenot, Jerome; Herzig, Karl-Heinz; Heljasvaara, Ritva Leena; Pihlajaniemi, Taina (Journal article; Peer reviewed, 2020)
      Liver and adipose tissues play important roles in the regulation of systemic glucose and lipid metabolism. Extracellular matrix synthesis and remodelling are significantly altered in these tissues in obesity and type 2 ...

    • Toward understanding scarless skin wound healing and pathological scarring 

      Karppinen, Sanna-Maria; Heljasvaara, Ritva Leena; Gullberg, Donald; Tasanen, Kaisa; Pihlajaniemi, Taina (Peer reviewed; Journal article, 2019)
      The efficient healing of skin wounds is crucial for securing the vital barrier function of the skin, but pathological wound healing and scar formation are major medical problems causing both physiological and psychological ...

    • Upregulated integrin α11 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis 

      Martínez-Nieto, Guillermo A.; Teppo, Hanna-Riikka; Petrelius, Noora; Izzi, Valerio; Devarajan, Raman; Petäistö, Tiina; Liu, Hengshuo; Kim, Kris S.; Karppinen, Sanna-Maria; Ruotsalainen, Heli; Koivunen, Jarkko; Mäki, Joni M.; Walker, Gilbert C.; Pihlajaniemi, Taina; Gullberg, Elon Donald; Heljasvaara, Ritva Leena (Journal article; Peer reviewed, 2022)
      Integrin α11β1 is a collagen-binding integrin that is needed to induce and maintain the myofibroblast phenotype in fibrotic tissues and during wound healing. The expression of the α11 is upregulated in cancer-associated ...