Blar i Department of Biomedicine på forfatter "Vareecal Joseph, Justin"

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    • GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity 

      Watson, Dionysios C.; Bayik, Defne; Storevik, Simon Humberto; Moreino, Shannon Sherwin; Sprowls, Samuel A.; Han, Jianhua; Augustsson, Mina Thue; Lauko, Adam; Sravya, Palavalasa; Røsland, Gro Vatne; Troike, Katie; Tronstad, Karl Johan; Wang, Sabrina; Sarnow, Katharina; Kay, Kristen; Lunavat, Taral; Silver, Daniel J.; Dayal, Sahil; Vareecal Joseph, Justin; Mulkearns-Hubert, Erin; Ystaas, Lars Andreas Rømo; Deshpande, Gauravi; Guyon, Joris; Zhou, Yadi; Magaut, Capucine R.; Seder, Juliana; Neises, Laura; Williford, Sarah E.; Meiser, Johannes; Scott, Andrew J.; Sajjakulnukit, Peter; Mears, Jason A.; Bjerkvig, Rolf; Chakraborty, Abhishek; Daubon, Thomas; Cheng, Feixiong; Lyssiotis, Costas A.; Wahl, Daniel R.; Hjelmeland, Anita B.; Hossain, Md Jubayer al; Miletic, Hrvoje; Lathia, Justin D. (Journal article; Peer reviewed, 2023)
      The transfer of intact mitochondria between heterogeneous cell types has been confirmed in various settings, including cancer. However, the functional implications of mitochondria transfer on tumor biology are poorly ...

    • Long-term treatment with valganciclovir improves lentiviral suicide gene therapy of glioblastoma 

      Hossain, Jubayer; Latif, Md Abdul; Ystaas, Lars Andreas Rømo; Ninzima, Sandra; Riecken, Kristoffer; Muller, Arnaud; Azuaje, Fransisco; Vareecal Joseph, Justin; Talasila, Krishna Mukharji; Ghimire, Jiwan; Fehse, Boris; Bjerkvig, Rolf; Miletic, Hrvoje (Peer reviewed; Journal article, 2019)
      Background: Suicide gene therapy for malignant gliomas has shown encouraging results in the latest clinical trials. However, prodrug application was most often restricted to short-term treatment (14 days), especially when ...

    • Pretreatment of glioblastoma with bortezomib potentiates natural killer cell cytotoxicity through TRAIL/DR5 mediated apoptosis and prolongs animal survival 

      Gras Navarro, Andrea; Espedal, Heidi; Vareecal Joseph, Justin; Moncho, Laura Trachsel; Bahador, Marzieh; Gjertsen, Bjørn Tore; Kristoffersen, Einar Klæboe; Simonsen, Anne; Miletic, Hrvoje; Enger, Per Øyvind; Rahman, Mohummad Aminur; Enger, Martha Chekenya (Peer reviewed; Journal article, 2019-07-17)
      Background: Natural killer (NK) cells are potential effectors in anti-cancer immunotherapy; however only a subset potently kills cancer cells. Here, we examined whether pretreatment of glioblastoma (GBM) with the proteasome ...