Browsing Department of Biomedicine by Journals "F1000 Research"
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Crystal structure of Pseudomonas aeruginosa FabB C161A, a template for structure-based design for new antibiotics
(Journal article; Peer reviewed, 2022)Background: FabB (3-oxoacyl-[acyl-carrier-protein] synthase 1) is part of the fatty acid synthesis II pathway found in bacteria and a potential target for antibiotics. The enzyme catalyses the Claisen condensation of ... -
Toward understanding scarless skin wound healing and pathological scarring
(Peer reviewed; Journal article, 2019)The efficient healing of skin wounds is crucial for securing the vital barrier function of the skin, but pathological wound healing and scar formation are major medical problems causing both physiological and psychological ...