Browsing Department of Biomedicine by Subject "long-term synaptic potentiation"

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    • The RNA-Binding Protein hnRNP K Mediates the Effect of BDNF on Dendritic mRNA Metabolism and Regulates Synaptic NMDA Receptors in Hippocampal Neurons 

      Leal, Graciano; Comprido, Diogo; de Luca, Pasqualino; Morais, Eduardo; Rodrigues, Luís; Mele, Miranda; Santos, Ana R.; Costa, Rui O.; Pinto, Maria Joana; Patil, Sudarshan; Berentsen, Birgitte; Afonso, Pedro; Carreto, Laura; Li, Ka Wan; Pinheiro, Paulo; Almeida, Ramiro D.; Santos, Manuel A. S.; Bramham, Clive R.; Duarte, Carlos B. (Peer reviewed; Journal article, 2017-11)
      Brain-derived neurotrophic factor (BDNF) is an important mediator of long-term synaptic potentiation (LTP) in the hippocampus. The local effects of BDNF depend on the activation of translation activity, which requires the ...