Blar i Department of Global Public Health and Primary Care på forfatter "Fadnes, Lars T."
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How the Norwegian population was affected by non-pharmaceutical interventions during the first six weeks of the COVID-19 lockdown
Mæland, Silje; Bjørknes, Ragnhild; Lehmann, Stine; Sandal, Gro Mjeldheim; Hazell, William; Rabben, Åsgeir Kjetland; Vedaa, Øystein; Skogen, Jens Christoffer; Fadnes, Lars T. (Journal article; Peer reviewed, 2021)Aims The aim of this study was to examine how the Norwegian general adult population was affected by non-pharmaceutical interventions during the first six weeks of the COVID-19 lockdown. We assessed quarantine, symptoms, ... -
Impact of clinical and sociodemographic factors on fatigue among patients with substance use disorder: a cohort study from Norway for the period 2016–2020
Vold, Jørn Henrik; Gjestad, Rolf; Aas, Christer Frode; Chalabianloo, Fatemeh; Skurtveit, Svetlana; Løberg, Else-Marie; Johansson, Kjell Arne; Fadnes, Lars T. (Journal article; Peer reviewed, 2020)Background The impact of clinical and sociodemographic factors on fatigue remains unknown among patients with substance use disorders (SUD). This study aims to evaluate fatigue among patients with SUD using a nine-item ... -
Impact of liver fibrosis and clinical characteristics on dose-adjusted serum methadone concentrations
Chalabianloo, Fatemeh; Høiseth, Gudrun; Vold, Jørn Henrik; Johansson, Kjell Arne; Kringen, Marianne K.; Dalgard, Olav; Ohldieck, Christian; Druckrey-Fiskaaen, Karl Trygve; Aas, Christer Frode; Løberg, Else-Marie; Bramness, Jørgen Gustav; Fadnes, Lars T. (Journal article; Peer reviewed, 2023)Background: There is limited knowledge on the causes of large variations in serum methadone concentrations and dose requirements. Objectives: We investigated the impact of the degree of liver fibrosis on dose-adjusted ... -
Integrated care of severe infectious diseases to people with substance use disorders; a systematic review
Vold, Jørn Henrik; Aas, Christer Frode; Leiva, Rafael Alexander Mo; Vickerman, Peter; Chalabianloo, Fatemeh; Løberg, Else-Marie; Johansson, Kjell Arne; Fadnes, Lars T. (Peer reviewed; Journal article, 2019)Background: Various integrated care models have been used to improve treatment completion of medications for chronic hepatitis B virus (HBV), chronic hepatitis C virus (HCV), Mycobacterium tuberculosis (TB), and Human ... -
Integrated treatment of hepatitis C virus infection among people who inject drugs: A multicenter randomized controlled trial (INTRO-HCV)
Fadnes, Lars T.; Aas, Christer Frode; Vold, Jørn Henrik; Leiva, Rafael Alexander Mo; Ohldieck, Christian; Chalabianloo, Fatemeh; Skurtveit, Svetlana Ondrasova; Lygren, Ole Jørgen; Dalgard, Olav; Vickerman, Peter; Midgard, Håvard; Løberg, Else-Marie; Johansson, Kjell Arne (Journal article; Peer reviewed, 2021)Background The standard pathways of testing and treatment for hepatitis C virus (HCV) infection in tertiary healthcare are not easily accessed by people who inject drugs (PWID). The aim of this study was to evaluate the ... -
Integrated treatment of hepatitis C virus infection among people who inject drugs: study protocol for a randomised controlled trial (INTRO-HCV)
Fadnes, Lars T.; Aas, Christer Frode; Vold, Jørn Henrik; Ohldieck, Christian; Leiva, Rafael Alexander Mo; Chalabianloo, Fatemeh; Skurtveit, Svetlana; Lygren, Ole Jørgen; Dalgard, Olav; Vickerman, Peter; Midgard, Håvard; Løberg, Else-Marie; Johansson, Kjell Arne (Peer reviewed; Journal article, 2019-11-08)Background: A large proportion of people who inject drugs (PWID) living with hepatitis C virus (HCV) infection have not been treated. It is unknown whether inclusion of HCV diagnostics and treatment into integrated substance ... -
Integration of smoking cessation into standard treatment for patients receiving opioid agonist therapy who are smoking tobacco: protocol for a randomised controlled trial (ATLAS4LAR)
Druckrey-Fiskaaen, Karl Trygve; Furulund, Einar; Daltveit, Jan Tore; Vold, Jørn Henrik; Lid, Torgeir Gilje; Madebo, Tesfaye; Fadnes, Lars T.; Buljovcic, Vibeke Bråthen (Journal article; Peer reviewed, 2022)Background About 85% of patients receiving opioid agonist therapy (OAT) for opioid dependence are smoking tobacco. Although smoke-related pulmonary diseases are significant contributors to morbidity and mortality, few ... -
Nut consumption and risk of cardiovascular disease, total cancer, all-cause and cause-specific mortality: a systematic review and dose-response meta-analysis of prospective studies
Aune, Dagfinn; Keum, NaNa; Giovannucci, Edward; Fadnes, Lars T.; Boffetta, Paolo; Greenwood, Darren C; Tonstad, Serena; Vatten, Lars Johan; Riboli, Elio; Norat, Teresa (Journal article; Peer reviewed, 2016)Background: Although nut consumption has been associated with a reduced risk of cardiovascular disease and all-cause mortality, data on less common causes of death has not been systematically assessed. Previous reviews ... -
On the path towards universal coverage of hepatitis C treatment among people receiving opioid agonist therapy (OAT) in Norway: A prospective cohort study from 2013 to 2017
Aas, Christer Frode; Vold, Jørn Henrik; Skurtveit, Svetlana; Odsbu, Ingvild; Chalabianloo, Fatemeh; Økland, Jan-Magnus; Leiva, Rafael Alexander Mo; Vickerman, Peter; Johansson, Kjell Arne; Fadnes, Lars T. (Journal article; Peer reviewed, 2020)Objectives We aimed to calculate cumulative hepatitis C virus (HCV) treatment coverage among individuals enrolled in opioid agonist therapy (OAT) in Norway between 2013 and 2017 and to document the treatment transition to ... -
Potentially addictive drugs dispensing to patients receiving opioid agonist therapy: a register-based prospective cohort study in Norway and Sweden from 2015 to 2017
Vold, Jørn Henrik; Aas, Christer Frode; Skurtveit, Svetlana; Odsbu, Ingvild; Chalabianloo, Fatemeh; Reutfors, Johan; Halmøy, Anne; Johansson, Kjell Arne; Fadnes, Lars T. (Journal article; Peer reviewed, 2020)Objectives: To compare the use of benzodiazepines, z-hypnotics, gabapentinoids, opioids and centrally acting stimulants (CAS) among patients who had received opioid agonist therapy (OAT) in Norway and Sweden during the ... -
Prevalence and correlates of suicide attempts in high-risk populations: a cross-sectional study among patients receiving opioid agonist therapy in Norway
Vold, Jørn Henrik; Løberg, Else-Marie; Aas, Christer Frode; Steier, Jan Alexander; Johansson, Kjell Arne; Fadnes, Lars T. (Journal article; Peer reviewed, 2022)Background Death by suicide in patients enrolled in opioid agonist therapy (OAT) is a major clinical concern. However, little knowledge exists regarding suicide attempts in this patient group. This study presents the ... -
Risk of Relapse Among Opioid‐Dependent Patients Treated With Extended‐Release Naltrexone or Buprenorphine‐Naloxone: A Randomized Clinical Trial
Opheim, Arild; Gaulen, Zhanna; Solli, Kristin Klemmetsby; Latif, Zill-E-Huma; Fadnes, Lars T.; Saltyte Benth, Jurate; Kunøe, Nikolaj; Tanum, Lars Håkon Reiestad (Journal article; Peer reviewed, 2021)Background and Objectives: Compare the risk of relapse to heroin and other illicit opioids among opioid-dependent patients receiving treatment with extended-release naltrexone (XR-NTX) or buprenorphine-naloxone ... -
Risk of relapse to non-opioid addictive substances among opioid dependent patients treated with an opioid receptor antagonist or a partial agonist: A randomized clinical trial
Opheim, Arild; Saltyte Benth, Jurate; Solli, Kristin Klemmetsby; Kloster, Pia Synnøve; Fadnes, Lars T.; Kunøe, Nikolaj; Gaulen, Zhanna; Tanum, Lars Håkon Reiestad (Journal article; Peer reviewed, 2023)Background and objective First study to assess any compensatory increase in use of non-opioid illicit substances and alcohol in opioid dependent patients randomized to treatment with extended-release naltrexone (XR-NTX) ... -
Subjective symptoms and serum methadone concentrations: what should guide dose adjustments in methadone maintenance treatment? A naturalistic cohort study from Norway
Chalabianloo, Fatemeh; Fadnes, Lars T.; Høiseth, Gudrun; Ohldieck, Christian; Vold, Jørn Henrik; Aas, Christer Frode; Løberg, Else-Marie; Johansson, Kjell Arne; Bramness, Jørgen Gustav (Journal article; Peer reviewed, 2021)Background: There is little evidence-based guidance on how to optimize methadone dosages among patients with opioid addiction undergoing methadone maintenance treatment (MMT). This study aims to investigate whether ... -
Substance use and symptoms of mental health disorders: a prospective cohort of patients with severe substance use disorders in Norway
Aas, Christer Frode; Vold, Jørn Henrik; Gjestad, Rolf; Skurtveit, Svetlana; Lim, Aaron G.; Gjerde, Kristian Varden; Løberg, Else-Marie; Johansson, Kjell Arne; Fadnes, Lars T. (Journal article; Peer reviewed, 2021-02-27)Background:There is high co-occurrence of substance use disorders (SUD) and mental health disorders. We aimedto assess impact of substance use patterns and sociodemographic factors on mental health distress using the ... -
Uptake and predictors of direct-acting antiviral treatment for hepatitis C among people receiving opioid agonist therapy in Sweden and Norway: a drug utilization study from 2014 to 2017
Aas, Christer Frode; Vold, Jørn Henrik; Skurtveit, Svetlana; Odsbu, Ingvild; Chalabianloo, Fatemeh; Lim, Aaron G.; Johansson, Kjell Arne; Fadnes, Lars T. (Journal article; Peer reviewed, 2020)Background Treatment with direct-acting antiviral agents (DAAs) offers an opportunity to eliminate hepatitis C virus (HCV) endemic among people who inject drugs (PWID) and people enrolled in opioid agonist therapy (OAT) ... -
Vitamin B12 Levels, Substance Use Patterns and Clinical Characteristics among People with Severe Substance Use Disorders: A Cohort Study from Western Norway
Madebo, Tesfaye; Mitra, Bemanian; Vold, Jørn Henrik; Chowdhury, Ranadip; Aas, Christer Frode; Druckrey-Fiskaaen, Karl Trygve; Johansson, Kjell Arne; Fadnes, Lars T. (Journal article; Peer reviewed, 2022)People with severe substance use disorder (SUD) have a higher burden of micronutrient deficiency compared with the general population. The aim of this study was to investigate vitamin B12 status and risk factors of deficiency ... -
Vitamin D status and associations with substance use patterns among people with severe substance use disorders in Western Norway
Mitra, Bemanian; Chowdhury, Ranadip; Stokke, Krister; Aas, Christer Frode; Johansson, Kjell Arne; Vold, Jørn Henrik; Fadnes, Lars T. (Journal article; Peer reviewed, 2022)Chronic and harmful substance use is associated with a cluster of harms to health, including micronutrient deficiencies. Maintaining adequate levels of vitamin D is important for musculoskeletal and other aspects of health. ...