Browsing Department of Clinical Medicine by Title
Now showing items 338-357 of 1329
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Early aseptic loosening of a mobile-bearing total knee replacement
(Peer reviewed; Journal article, 2017)Background and purpose - Registry-based studies have reported an increased risk of aseptic tibial loosening for the cemented Low Contact Stress (LCS) total knee replacement compared with other cemented designs; however, ... -
Early constipation predicts faster dementia onset in Parkinson's disease
(Journal article; Peer reviewed, 2021)Constipation is a common but not a universal feature in early PD, suggesting that gut involvement is heterogeneous and may be part of a distinct PD subtype with prognostic implications. We analysed data from the Parkinson’s ... -
Early diagnosis is associated with improved clinical outcomes in benign esophageal perforation: an individual patient data meta‑analysis
(Journal article; Peer reviewed, 2020)Background Time of diagnosis (TOD) of benign esophageal perforation is regarded as an important risk factor for clinical outcome, although convincing evidence is lacking. The aim of this study is to assess whether time ... -
Early indicators of disease progression in Fabry disease that may indicate the need for disease-specific treatment initiation: Findings from the opinion-based PREDICT-FD modified Delphi consensus initiative
(Journal article; Peer reviewed, 2020)Objectives The PRoposing Early Disease Indicators for Clinical Tracking in Fabry Disease (PREDICT-FD) initiative aimed to reach consensus among a panel of global experts on early indicators of disease progression that may ... -
Early neurological worsening in acute ischaemic stroke patients
(Peer reviewed; Journal article, 2016-01)Objectives: Neurological worsening in acute ischaemic stroke patients is common with significant morbidity and mortality. Aims: To determine the factors associated with early neurological worsening within the first 9 h ... -
Early Parkinson’s Disease. Incidence, clinical features and quality of life in a population-based cohort study.
(Doctoral thesis, 2014-06-06)Background: The prevalence of Parkinson’s Disease (PD) in Norway is about 100/100 000 inhabitants. For planning of health care needs and for research purposes, incidence figures are considered the more valuable information, ... -
Early substance use cessation improves cognition-10 years outcome in first-episode psychosis patients
(Peer reviewed; Journal article, 2019-07-12)Background: Cognitive impairment may be a risk factor for, as well as a consequence of, psychosis. Non-remitting symptoms, premorbid functioning, level of education, and socioeconomic background are known correlates. A ... -
Economic aspects of Parkinson’s disease
(Doctoral thesis, 2009-11-13)Background: Next to Alzheimer’s disease, Parkinson’s disease (PD) is the second most neurodegenerative disease. As the population structure in the industrialized and industrializing countries is changing, an increasing ... -
The economic impact of multiple sclerosis to the patients and their families in Norway
(Peer reviewed; Journal article, 2018-12)Background: Multiple sclerosis (MS) imposes high economic costs on society, but the patients and their families have to bear some of these costs. Objective: We aimed to estimate the magnitude of these economic costs in ... -
An economic model to evaluate cost-effectiveness of computer assisted knee replacement surgery in Norway
(Peer reviewed; Journal article, 2013-07-06)Background: The use of Computer Assisted Surgery (CAS) for knee replacements is intended to improve the alignment of knee prostheses in order to reduce the number of revision operations. Is the cost effectiveness of computer ... -
Editorial: facts, figures and the future
(Peer reviewed; Journal article, 2015-01-09) -
Efect of high intake of cod or salmon on serum total neopterin concentration: a randomised clinical trial
(Journal article; Peer reviewed, 2021)Purpose Primarily, to investigate the effect of high intake of cod (lean fish) or salmon (fatty fish) on serum concentration of total neopterin, a marker of cellular immune activation that is associated with cardiovascular ... -
Effect of a cod protein hydrolysate on postprandial glucose metabolism in healthy subjects: A double-blind cross-over trial
(Peer reviewed; Journal article, 2018)The increased prevalence of lifestyle diseases, such as the metabolic syndrome and type 2 diabetes mellitus (T2DM), calls for more knowledge on dietary treatments targeting the specific metabolic pathways involved in these ... -
The effect of a low FODMAP diet in addition to a gluten free diet on symptoms and quality of life in patients with coeliac disease and IBS-like symptoms: A randomized, controlled clinical study
(Master thesis, 2016-05-17)Around 20-30% of coeliac disease patients have IBS-like symptoms. The low FODMAP diet (low in fermentable oligo-, di-, monosaccharides and polyols) is used as treatment for irritable bowel syndrome (IBS) to reduce ... -
Effect of Ascaris Lumbricoides specific IgE ontuberculin skin test responses in children in a high-burdensetting: a cross-sectional community-based study
(Peer reviewed; Journal article, 2012-09-11)Background: M.tuberculosis (M.tb) is associated with enhanced T helper cell type 1 (Th1) immune responses while helminth infection is associated with T helper cell type 2 (Th2) immune responses. Our aim was to investigate ... -
Effect of cod residual protein supplementation on markers of glucose regulation in lean adults: A randomized double-blind study
(Journal article; Peer reviewed, 2020)Large quantities of protein-rich cod residuals, which are currently discarded, could be utilized for human consumption. Although fish fillet intake is related to beneficial health effects, little is known about the potential ... -
Effect of dietary management on the gastric endocrine cells in patients with irritable bowel syndrome
(Peer reviewed; Journal article, 2014-08-06)Background/objectives: The gastric endocrine cells in patients with irritable bowel syndrome (IBS) tend to normalize following dietary guidance. The aim of the present study was to identify the gastric endocrine cell types ... -
The effect of fixation type on the survivorship of contemporary total knee arthroplasty in patients younger than 65 years of age: a register-based study of 115,177 knees in the Nordic Arthroplasty Register Association (NARA) 2000–2016
(Journal article; Peer reviewed, 2020)Background and purpose — Cemented fixation is regarded as the gold standard in total knee arthroplasty (TKA). Among working-age patients, there has been controversy regarding the optimal fixation method in TKA. To address ... -
The effect of infliximab in patients with chronic low back pain and Modic changes (the BackToBasic study): study protocol of a randomized, double blind, placebo-controlled, multicenter trial
(Journal article; Peer reviewed, 2020)Background Low back pain is common and a significant number of patients experience chronic low back pain. Current treatment options offer small to moderate effects. Patients with vertebral bone marrow lesions visualized ... -
The effect of influenza virus vaccine formulation : a potential for increased vaccine efficacy
(Doctoral thesis, 2005-12-16)Influenza remains one of the most serious viral diseases in the world, causing substantial morbidity and is responsible for at least one million deaths annually. A vast influenza virus reservoir exists in birds to which ...