Now showing items 975-994 of 2084

    • Identification of diagnostic and prognostic biomarkers of PD using a multiplex proteomics approach 

      Maple-Grødem, Jodi; Ushakova, Anastasia; Pedersen, Kenn Freddy; Tysnes, Ole-Bjørn; Alves, Guido Werner; Lange, Johannes (Journal article; Peer reviewed, 2023)
      Given the complexity of Parkinson's disease (PD), achieving acceptable diagnostic and prognostic accuracy will require the support of a panel of diverse biomarkers. We used Proximity extension assays to measure a panel of ...
    • Identification of novel genomic risk loci shared between common epilepsies and psychiatric disorders 

      Karadag, Naz; Shadrin, Alexey; O'Connell, Kevin S; Hindley, Guy Frederick Lanyon; Rahman, Zillur; Parker, Nadine; Bahrami, Shahram; Fominykh, Vera; Cheng, Weiqiu; Holen, Børge; Alvestad, Silje; Taubøll, Erik; Steen, Nils Eiel; Djurovic, Srdjan; Dale, Anders M; Frei, Oleksandr; Andreassen, Ole; Smeland, Olav Bjerkehagen (Journal article; Peer reviewed, 2023)
      Psychiatric disorders and common epilepsies are heritable disorders with a high comorbidity and overlapping symptoms. However, the causative mechanisms underlying this relationship are poorly understood. Here we aimed to ...
    • Identifying possible biomarkers of lower urinary tract symptoms using metabolomics and partial least square regression 

      Hopland-Nechita, Florin Vasile; Andersen, John Roger; Rajalahti, Tarja; Andreassen, Trygve; Beisland, Christian (Journal article; Peer reviewed, 2023)
      Introduction The objective of this study was to explore potential novel biomarkers for moderate to severe lower urinary tract symptoms (LUTS) using a metabolomics-based approach, and statistical methods with significant ...
    • Identity-by-descent mapping in a Scandinavian multiple sclerosis cohort 

      Westerlind, Helga; Imrell, Kerstin; Ramanujam, Ryan; Myhr, Kjell-Morten; Celius, Elisabeth Gulowsen; Harbo, Hanne Flinstad; Oturai, Annette Bang; Hamsten, Anders; Alfredsson, Lars; Olsson, Tomas; Kockum, Ingrid; Koski, Timo; Hillert, Jan (Peer reviewed; Journal article, 2015)
      In an attempt to map chromosomal regions carrying rare gene variants contributing to the risk of multiple sclerosis (MS), we identified segments shared identical-by-descent (IBD) using the software BEAGLE 4.0’s refined IBD ...
    • An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver 

      Fernández Moro, Carlos; Geyer, Natalie; Harrizi, Sara; Hamidi, Yousra; Söderqvist, Sara; Kuznyecov, Danyil; Tidholm Qvist, Evelina; Salmonson Schaad, Media; Hermann, Laura; Lindberg, Amanda; Heuchel, Rainer L.; Martín-Bernabé, Alfonso; Dhanjal, Soniya; Navis, Anna C.; Villard, Christina; del Valle, Andrea C.; Bozóky, Lorand; Sparrelid, Ernesto; Dirix, Luc; Strell, Carina; Östman, Arne; Schmierer, Bernhard; Vermeulen, Peter B.; Engstrand, Jennie; Bozóky, Béla; Gerling, Marco (Journal article; Peer reviewed, 2023)
      A perimetastatic capsule is a strong positive prognostic factor in liver metastases, but its origin remains unclear. Here, we systematically quantify the capsule’s extent and cellular composition in 263 patients with ...
    • IgA-nefropati 

      Haaskjold, Yngvar Lunde; Knoop, Thomas (Journal article; Peer reviewed, 2022)
      Immunglobulin A-nefropati (IgA-nefropati) er den vanligste formen for primær glomerulonefritt i verden og en hyppig årsak til alvorlig nyresvikt hos unge voksne. Diagnosen stilles ved nyrebiopsi. Til tross for at sykdommen ...
    • IGHV gene usage and mutational status in follicular lymphoma: Correlations with prognosis and patient age 

      Berget, Ellen; Molven, Anders; Løkeland, Turid; Helgeland, Lars; Vintermyr, Olav Karsten (Peer reviewed; Journal article, 2015-07)
      Follicular lymphoma (FL) is a heterogeneous disease with some patients developing progressively or transformed disease early, whereas others follow an indolent clinical course. We evaluated the prognostic value of ...
    • ILIVE Project Volunteer study. Developing international consensus for a European Core Curriculum for hospital end-of-life-care volunteer services, to train volunteers to support patients in the last weeks of life: A Delphi study 

      McGlinchey, Tamsin; Mason, Stephen R; Smeding, Ruthmarijke; Goosensen, Anne; Ruiz-Torreras, Inmaculada; Haugen, Dagny Renata Faksvåg; Bakan, Miša; Ellershaw, John E (Journal article; Peer reviewed, 2021)
      Background: Volunteers make a huge contribution to the health and wellbeing of the population and can improve satisfaction with care especially in the hospice setting. However, palliative and end-of-life-care volunteer ...
    • Illness perception in children with cerebral palsy, a longitudinal cohort study 

      Bjørgaas, Hanne Marit; Elgen, Irene Bircow; Hysing, Mari (Journal article; Peer reviewed, 2021)
      Background The perception of a disorder could be of importance both in problem solving behaviors, and in the emotional approach towards a disorder. Aims In this paper, we wanted to assess changes in illness perception ...
    • The Imaging and Cognition Genetics Conference 2011, ICG 2011: A Meeting of Minds 

      Le Hellard, Stephanie; Hanson, Isabel (Peer reviewed; Journal article, 2012-05-12)
      In June 2011, 70 researchers from the disciplines of cognitive science, genetics, psychology, psychiatry, neurobiology, and computer science gathered in Os, Norway, for the first Imaging and Cognition Genetics meeting. The ...
    • Imaging in Lyme neuroborreliosis 

      Lindland, Elisabeth Margrete Stokke; Solheim, Anne Marit; Andreassen, Silje; Paulsen, Else Quist; Eikeland, Randi; Ljøstad, Unn; Mygland, Åse; Elsais, Ahmed; Nygaard, Gro Owren; Lorentzen, Åslaug Rudjord; Harbo, Hanne Flinstad; Beyer, Mona K. (Peer reviewed; Journal article, 2018-10)
      Lyme neuroborreliosis (LNB) is a tick-borne spirochetal infection with a broad spectrum of imaging pathology. For individuals who live in or have travelled to areas where ticks reside, LNB should be considered among ...
    • Imaging of preclinical endometrial cancer models for monitoring tumor progression and response to targeted therapy 

      Espedal, Heidi; Fonnes, Tina; Fasmer, Kristine Eldevik; Krakstad, Camilla; Haldorsen, Ingfrid S. (Peer reviewed; Journal article, 2019-11-27)
      Endometrial cancer is the most common gynecologic malignancy in industrialized countries. Most patients are cured by surgery; however, about 15% of the patients develop recurrence with limited treatment options. Patient-derived ...
    • Imaging of the brain and of the lungs in young adults born prematurely and / or with a low birth weight. Radiological findings and associations with clinical features. 

      Aukland, Stein Magnus (Doctoral thesis, 2011-04-15)
      Background and Purpose: Premature birth is defined as a birth occurring earlier than 37 gestational weeks, and typically occurs in 6% of all pregnancies in Europe (1). All premature babies are at risk for health problems ...
    • Immediate and long-term impact of the COVID-19 pandemic on delivery of surgical services 

      Søreide, Kjetil; Hallet, Julie; Matthews, Jeffrey B.; Schnitzbauer, Andreas Anton; Line, Pål Dag; Lai, Paul B.S.; Otero, Javier; Callegaro, Dario; Warner, Shelley G.; Baxter, Nancy N.; Teh, Catherine S.C.; Ng-Kamstra, Joshua S.; Meara, John G.; Hagander, Lars E.; Lorenzon, Laura (Journal article; Peer reviewed, 2020)
      Background The ongoing pandemic is having a collateral health effect on delivery of surgical care to millions of patients. Very little is known about pandemic management and effects on other services, including delivery ...
    • Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies 

      Broce, Iris J.; Karch, Celeste M.; Wen, Natalie; Fan, Chun C.; Wang, Yunpeng; Hong Tan, Chin; Kouri, Naomi; Ross, Owen A.; Höglinger, Günter U.; Müller, Ulrich; Hardy, John; Momeni, Parastoo; Hess, Christopher P.; Dillon, William P.; Miller, Zachary A.; Bonham, Luke W.; Rabinovici, Gil D.; Rosen, Howard J.; Schellenberg, Gerard D.; Franke, Andre; Karlsen, Tom Hemming; Veldink, Jan H.; Ferrari, Raffaele; Yokoyama, Jennifer S.; Miller, Bruce L.; Andreassen, Ole Andreas; Dale, Anders; Desikan, Rahul S.; Sugrue, Leo P. (Peer reviewed; Journal article, 2018-01-09)
      Background: Converging evidence suggests that immune-mediated dysfunction plays an important role in the pathogenesis of frontotemporal dementia (FTD). Although genetic studies have shown that immune-associated loci are ...
    • The impact of age-related syndromes on ICU process and outcomes in very old patients 

      Vallet, Hélène; Guidet, Bertrand; Boumendil, Ariane; De Lange, Dylan W.; Leaver, Susannah; Szczeklik, Wojciech; Jung, Christian; Sviri, Sigal; Beil, Michael; Flaatten, Hans Kristian (Journal article; Peer reviewed, 2023)
      In this narrative review, we describe the most important age-related “syndromes” found in the old ICU patients. The syndromes are frailty, comorbidity, cognitive decline, malnutrition, sarcopenia, loss of functional autonomy, ...
    • Impact of birth weight on kidney health in middle-aged adults : Results from the Haugesund Low Birth Weight Study 

      Lillås, Bjørn Steinar Demma (Doctoral thesis, 2024-06-07)
      Bakgrunn: Tidligere studier, inkludert flere studier basert på medisinsk fødselsregister i Norge, har vist en sammenheng mellom lav fødselsvekt og redusert nyrefunksjon hos voksne. Studier som bruker målt glomerulær ...
    • Impact of body mass index and fat distribution on sex steroid levels in endometrial carcinoma: A retrospective study 

      van Weelden, Willem Jan; Fasmer, Kristine Eldevik; Tangen, Ingvild Løberg; IntHout, Joanna; Abbink, Karin; van Herwaarden, Antonius E.; Krakstad, Camilla; Massuger, Leon F.A.G.; Haldorsen, Ingfrid S.; Pijnenborg, Johanna M.A. (Peer reviewed; Journal article, 2019-06-07)
      Background Obesity is an important cause of multiple cancer types, amongst which endometrial cancer (EC). The relation between obesity and cancer is complicated and involves alterations in insulin metabolism, response to ...
    • Impact of childhood trauma on antipsychotic effectiveness in schizophrenia spectrum disorders: A prospective, pragmatic, semi-randomized trial 

      Mørkved, Nina; Johnsen, Erik; Kroken, Rune Andreas; Winje, Dagfinn; Larsen, Tor Ketil; Thimm, Jens; Rettenbacher, M.A.; Johannesen, C.A. Bartz; Løberg, Else-Marie (Journal article; Peer reviewed, 2022)
      Antipsychotic medications are generally effective in ameliorating psychotic symptoms in schizophrenia spectrum disorders (SSDs). Identifying predictors associated with poor treatment response is important for a personalized ...