• Month of birth and risk of multiple sclerosis: confoundingand adjustments 

      Torkildsen, Øivind Fredvik; Aarseth, Jan Harald; Benjaminsen, Espen; Celius, Elisabeth Gulowsen; Holmøy, Trygve; Kampman, Margitta Theodora; Løken-Amsrud, Kristin Ingeleiv; Midgard, Rune; Myhr, Kjell-Morten; Riise, Trond; Torkildsen, Nina Agnethe Grytten (Peer reviewed; Journal article, 2014-02)
      A month of birth effect on multiple sclerosis (MS) risk has been reported from different countries. Recent critics have suggested that this finding is caused by confounding and that adequately adjusting for year and place ...
    • Morbidity and Mortality after Emergency and Urgent Colorectal Surgery for Malignant and Benign Disease 

      Ellensen, Vegard Skalstad; Elshove-Bolk, Jolande; Baatrup, Gunnar (Peer reviewed; Journal article, 2009)
      Abstract: Aim: The aim of this study was to determine short and long-term morbidity and mortality rates after emergency colorectal surgery for benign and malignant disease in a high volume tertiary referral hospital in ...
    • More Than Fish—Framing Aquatic Animals within Sustainable Food Systems 

      Pounds, Alexandra; Kaminski, Alexander M.; Budhathoki, Mausam; Gudbrandsen, Oddrun Anita; Kok, Björn; Horn, Stephanie; Malcorps, Wesley; Mamun, Abdullah-Al; McGoohan, Amy; Newton, Richard; Ozretich, Reed; Little, David C. (Journal article; Peer reviewed, 2022)
      Aquatic animals are diverse in terms of species, but also in terms of production systems, the people involved, and the benefits achieved. In this concept piece, we draw on literature to outline how the diversity of aquatic ...
    • Mortality after hospital admission for trauma in Norway: A retrospective observational national cohort study 

      Dehli, Trond; Wisborg, Torben; Johnsen, Lars Gunnar; Brattebø, Guttorm; Eken, Torsten (Journal article; Peer reviewed, 2023)
      Background: National quality data for trauma care in Norway have not previously been reported. We have therefore assessed crude and risk-adjusted 30-day mortality in trauma cases after primary hospital admission on national ...
    • Mortality among retired offshore divers in Norway 

      Irgens, Ågot; Djurhuus, Rune; Grønning, Marit (Peer reviewed; Journal article, 2015)
      Background: Health effects of diving have been observed in divers who have not experienced any diving related accidents. The aim of the study was to study total, and cause specific mortality, in Norwegian retired professional ...
    • Mortality and cause of death in multiple sclerosis in western Norway 1950-2021: A registry-based linkage study 

      Willumsen, Johannes Sverre; Grytten, Nina; Aarseth, Jan Harald; Myklebust, Tor Åge; Myhr, Kjell-Morten; Midgard, Rune (Journal article; Peer reviewed, 2022)
      Background Persons with multiple sclerosis (pwMS) have higher risk of mortality compared with the general population. Longitudinal studies are important for understanding the evolution of survival in pwMS. Objective ...
    • Mortality and non-use of antipsychotic drugs after acute admission in schizophrenia: A prospective total-cohort study 

      Strømme, Maria Fagerbakke; Mellesdal, Liv Solrunn; Bartz-Johannesen, Christoffer; Kroken, Rune Andreas; Krogenes, Marianne; Mehlum, Lars; Johnsen, Erik (Journal article; Peer reviewed, 2021)
      Background In society at large, it is debated whether use of antipsychotic drugs is associated with increased or decreased mortality among patients with schizophrenia. Large register studies have demonstrated an increased ...
    • Mortality in epilepsy and the influence of comorbid conditions and antiepileptic drugs 

      Aurlien, Dag (Doctoral thesis, 2013-05-31)
      Purpose: Based on a clinical observation, this study was initiated to examine whether treatment with lamotrigine (LTG) is associated with an increased risk of sudden unexpected death in epilepsy (SUDEP) in sub-groups of ...
    • Mortality trends of amyotrophic lateral sclerosis in Norway 1951–2014: an age–period–cohort study 

      Nakken, Ola; Lindstrøm, Jonas Christoffer; Tysnes, Ole-Bjørn; Holmøy, Trygve (Peer reviewed; Journal article, 2016-12)
      Recent studies suggest that the incidence and mortality of amyotrophic lateral sclerosis (ALS) are increasing. Changing environmental factors could influence disease risk differently throughout life span, and also between ...
    • Mosaicism for combined tetrasomy of chromosomes 8 and 18 in a dysmorphic child: A result of failed tetraploidy correction? 

      Houge, Gunnar; Lybæk, Helle; Gulati, Sasha (Peer reviewed; Journal article, 2009-05-18)
      Background: Mosaic whole-chromosome tetrasomy has not previously been described as a cause of fetal malformations. Case presentation: In a markedly dysmorphic child with heart malformations and developmental delay, CGH ...
    • Mosaicism of podocyte involvement is related to podocyte injury in females with Fabry disease 

      Mauer, Michael; Glynn, Emily; Svarstad, Einar; Tøndel, Camilla; Gubler, Marie-Claire; West, Michael; Sokolovskiy, Alexey; Whitley, Chester; Najafian, Behzad (Peer reviewed; Journal article, 2014-11-11)
      Background: Fabry disease. an X-linked deficiency of α-galactosidase A coded by the GLA gene, leads to intracellular globotriaosylceramide (GL-3) accumulation. Although less common than in males, chronic kidney disease, ...
    • Motor activity patterns in acute schizophrenia and other psychotic disorders can be differentiated from bipolar mania and unipolar depression 

      Krane-Gartiser, Karoline; Henriksen, Tone Elise Gjøtterud; Morken, Gunnar; Vaaler, Arne; Fasmer, Ole Bernt (Peer reviewed; Journal article, 2018-12)
      The purpose of this study was to compare 24-h motor activity patterns between and within three groups of acutely admitted inpatients with schizophrenia and psychotic disorders (n = 28), bipolar mania (n = 18) and motor-retarded ...
    • MRI characterisation of adult onset alpha-methylacyl-coA racemase deficiency diagnosed by exome sequencing 

      Haugarvoll, Kristoffer; Johansson, Stefan; Tzoulis, Charalampos; Haukanes, Bjørn Ivar; Bredrup, Cecilie; Neckelmann, Gesche; Boman, Helge; Knappskog, Per; Bindoff, Laurence (Peer reviewed; Journal article, 2013-01-03)
      Background: Correct diagnosis is pivotal to understand and treat neurological disease. Herein, we report the diagnostic work-up utilizing exome sequencing and the characterization of clinical features and brain MRI in two ...
    • MRI findings in candidates for lumbar disc prosthesis: reliability and relationship to disability and pain 

      Berg, Linda (Doctoral thesis, 2014-11-21)
      Background and objective: In candidates for lumbar disc prosthesis, limited reliability data exist for magnetic resonance imaging (MRI) findings relevant to planning of treatment and to evaluation of outcome after treatment. ...
    • MRI-assessed tumor-free distance to serosa predicts deep myometrial invasion and poor outcome in endometrial cancer 

      Dybvik, Julie Andrea; Fasmer, Kristine Eldevik; Ytre-Hauge, Sigmund; Husby, Jenny Hild Aase; Salvesen, Øyvind; Stefansson, Ingunn Marie; Krakstad, Camilla; Trovik, Jone; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2022)
      Objectives To explore the diagnostic accuracy of preoperative magnetic resonance imaging (MRI)-derived tumor measurements for the prediction of histopathological deep (≥ 50%) myometrial invasion (pDMI) and prognostication ...
    • An mri-based radiomic prognostic index predicts poor outcome and specific genetic alterations in endometrial cancer 

      Jacob, Havjin; Dybvik, Julie Andrea; Ytre-Hauge, Sigmund; Fasmer, Kristine E.; Høivik, Erling Andre; Trovik, Jone; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2021)
      Integrative tumor characterization linking radiomic profiles to corresponding gene expression profiles has the potential to identify specific genetic alterations based on non-invasive radiomic profiling in cancer. The aim ...
    • MRPS23 amplification and gene expression in breast cancer; association with proliferation and the non-basal subtypes 

      Klæstad, Elise; Opdahl, Signe; Engstrøm, Monica J; Ytterhus, Borgny; Wik, Elisabeth; Bofin, Anna Mary; Valla, Marit (Journal article; Peer reviewed, 2020-01-16)
      Purpose MRPS23 is recognized as a driver of proliferation in luminal breast cancer. The aims of the present study were to describe MRPS23 copy number change in breast cancer, and to assess associations between MRPS23 copy ...
    • mtDNA nt13708A Variant Increases the Risk of Multiple Sclerosis 

      Yu, Xinhua; Koczan, Dirk; Sulonen, Anna-Maija; Akkad, Denis A.; Kroner, Antje; Comabella, Manuel; Costa, Gianna; Corongiu, Daniela; Goertsches, Robert; Camina-Tato, Montserrat; Thiese, Hans-Juergen; Nyland, Harald Inge; Mørk, Sverre; Montalban, Xavier; Rieckmann, Peter; Marrosu, Maria G.; Myhr, Kjell-Morten; Epplen, Joerg T.; Saarela, Sanna; Ibrahim, Saleh M. (Peer reviewed; Journal article, 2008-02-13)
      Background: Mitochondrial DNA (mtDNA) polymorphism is a possible factor contributing to the maternal parent-of-origin effect in multiple sclerosis (MS) susceptibility. Methods and Findings: In order to investigate the role ...
    • The mucinous domain of pancreatic carboxyl-ester lipase (CEL) contains core 1/core 2 O-glycans that can be modified by ABO blood group determinants 

      El Jellas, Khadija; Johansson, Bente Berg; Fjeld, Karianne; Antonopoulos, Aristotelis; Immervoll, Heike; Choi, Man Hung; Hoem, Dag; Lowe, Mark E.; Lombardo, Dominique; Njølstad, Pål Rasmus; Dell, Anne; Mas, Eric; Haslam, Stuart M.; Molven, Anders (Peer reviewed; Journal article, 2018)
      Carboxyl-ester lipase (CEL) is a pancreatic fat-digesting enzyme associated with human disease. Rare mutations in the CEL gene cause a syndrome of pancreatic exocrine and endocrine dysfunction denoted MODY8, whereas a ...
    • A multicenter study on Leigh syndrome: disease course and predictors of survival 

      Sofou, Kalliopi; De Coo, Irenaeus F. M.; Isohanni, Pirjo; Ostergaard, Elsebet; Naess, Karin; De Meirleir, Linda; Tzoulis, Charalampos; Uusimaa, Johanna; De Angst, Isabell B.; Lönnqvist, Tuula; Pihko, Helena; Mankinen, Katariina; Bindoff, Laurence; Tulinius, Már; Darin, Niklas (Peer reviewed; Journal article, 2014-04-15)
      Background: Leigh syndrome is a progressive neurodegenerative disorder, associated with primary or secondary dysfunction of the mitochondrial oxidative phosphorylation. Despite the fact that Leigh syndrome is the most ...