Browsing Department of Clinical Medicine by Title
Now showing items 1317-1336 of 1923
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A novel age-related gene expression signature associates with proliferation and disease progression in breast cancer
(Journal article; Peer reviewed, 2022)Background and objective Breast cancer (BC) diagnosed at ages <40 years presents with more aggressive tumour phenotypes and poorer clinical outcome compared to older BC patients. Here, we explored transcriptional BC ... -
Novel hybridization- and tag-based error-corrected method for sensitive ctDNA mutation detection using ion semiconductor sequencing
(Journal article; Peer reviewed, 2022)Circulating tumor DNA (ctDNA) analysis has emerged as a clinically useful tool for cancer diagnostics and treatment monitoring. However, ctDNA detection is complicated by low DNA concentrations and technical challenges. ... -
Novel Methods and Sources for Regeneration of Oral Mucosa
(Doctoral thesis, 2022-06-16)Background: Common clinical approaches for replacing damaged oral mucosa are represented by autologous skin grafts which have numerous shortcomings and pose serious post-surgical morbidity. Cultured oral mucosal sheets ... -
A novel MRI index for paraspinal muscle fatty infiltration: reliability and relation to pain and disability in lumbar spinal stenosis: results from a multicentre study
(Journal article; Peer reviewed, 2022)Background Fatty infiltration of the paraspinal muscles may play a role in pain and disability in lumbar spinal stenosis. We assessed the reliability and association with clinical symptoms of a method for assessing fatty ... -
Novel Nanoparticulate and Ionic Titanium Antigens for Hypersensitivity Testing
(Peer reviewed; Journal article, 2018-04-06)Titanium is used in a wide variety of materials ranging from medical devices to materials used in everyday life. Adverse biological reactions that could occur in patients, consumers, and workers should be monitored and ... -
NSAID use is not associated with Parkinson's disease incidence: A Norwegian Prescription Database study
(Journal article; Peer reviewed, 2021-09-07)Objective: Whether use of nonsteroidal anti-inflammatory drugs (NSAIDs) reduce the risk of incident Parkinson’s disease (PD) remains unresolved. Here, we employed the Norwegian Prescription Database to examine whether NSAID ... -
Nuclear and Mitochondrial Circulating Cell-Free DNA Is Increased in Patients With Inflammatory Bowel Disease in Clinical Remission
(Journal article; Peer reviewed, 2020)Background: The role of cell-free DNA (cfDNA) in the pathogenesis of inflammatory bowel disease (IBD) has been recently suggested. The aim of this study was to analyze circulating cfDNA and deoxyribonuclease (DNase) activity ... -
The Nurse Role in the Management of ADHD in Children and Adolescent: A Literature Review
(Journal article; Peer reviewed, 2022)Objective: To review literature regarding existing and recommended roles for nurses in the management of children with ADHD. Methods: MEDLINE and CINAHL were searched from 2010 to the end of 2019 with the following ... -
Nutrients and contaminants in processed small indigenous fish species from Ghana : Implications for food and nutrition security
(Doctoral thesis, 2022-04-07)The prevalence of malnutrition is increasing globally, along with the need to access nutritious, safe and sustainable foods. Fish are known as a rich source of protein, essential fatty acids and micronutrients, and including ... -
Nutrition Education as Part of a Cancer Rehabilitation Program: Evaluation of Short Term Efficacy
(Master thesis, 2018-06-22)Background and aim: The rising number of cancer patients is being followed by increasing number of cancer survivors in Norway. Modifiable lifestyle factors such as changing dietary behaviour can benefit the cancer prognosis ... -
Nutrition in the intensive care patient
(Master thesis, 2023-05-15)Introduction Nutritional therapy in critically ill patients requires recurring assessments to accommodate the increased nutritional demands alongside the decreased tolerance for receiving nutrition in the stress-induced ... -
Nutritional and clinical status of patients with diabetes in Zanzibar: A clinical follow up study
(Master thesis, 2020-06-24) -
Nutritional Screening and Treatment of Malnutrition at a Haematological Ward - An economical perspective
(Master thesis, 2016-05-18)When a patient is admitted to the hospital he or she should be screened for malnutrition within the first 24 hours. If the patient is identified as being at risk, appropriate treatment should be given, and then the patient ... -
The obesogenic effects of high-fat diets are influenced by both protein source and amount
(Master thesis, 2013-05-15)Although there has been a decline in the dietary fat intake over the last decade, the prevalence of obesity and type 2 diabetes is still rising. The contemporary Western diet provides an average of 49 % energy from ... -
The obesogenic potential of high fat/high protein diets is determined by both amino acid- and fatty acid composition of the protein source used
(Master thesis, 2016-05-12)Studies in rodents have found that high protein diets differ in obesogenic potential depending on the protein source used. Varied changes in morphology of brown adipose tissue, an important metabolic organ in mice and rats, ... -
Objective assessment of motor activity in a clinical sample of adults with attention-deficit/hyperactivity disorder and/or cyclothymic temperament
(Journal article; Peer reviewed, 2022)Background Most research on patterns of motor activity has been conducted on adults with mood disorders, but few studies have investigated comorbid attention-deficit/hyperactivity disorder (ADHD) or temperamental factors ... -
Observation or resection of pancreatic intraductal papillary mucinous neoplasm: An ongoing tug of war
(Peer reviewed; Journal article, 2019)An increasing number of patients are being referred to pancreatic centres around the world due to often incidentally discovered cystic neoplasms of the pancreas. The evaluation and management of pancreatic cystic neoplasms ... -
Obsessive-compulsive disorder (OCD) in patients with first- episode psychosis (FEP): A prospective study
(Peer reviewed; Journal article, 2014) -
Obstetric anal sphincter injuries. A population-based study of improvement of care
(Doctoral thesis, 2015-12-11)Background: Obstetric anal sphincter injuries (OASIS) are tears of the anal sphincters, eventually also involving the rectum, sustained during vaginal birth, and 30% to 50% of women experience anal incontinence (AI) after ...