Blar i Department of Clinical Medicine på tittel
Viser treff 1840-1859 av 2313
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Prospective cohort study of early biosignatures of response to lithium in bipolar-I-disorders: overview of the H2020-funded R-LiNK initiative
(Peer reviewed; Journal article, 2019-09-25)Background Lithium is recommended as a first line treatment for bipolar disorders. However, only 30% of patients show an optimal outcome and variability in lithium response and tolerability is poorly understood. It remains ... -
A prospective observational study of why people are medically evacuated from offshore installations in the North Sea
(Journal article; Peer reviewed, 2020)Objectives Few studies have described evacuations due to medical emergencies from the offshore installations in the North Sea, though efficient medical service is essential for the industrial activities in this area. The ... -
Prospective Study of Surgery for Traumatic Brain Injury in Addis Ababa, Ethiopia: Surgical Procedures, Complications, and Postoperative Outcomes
(Journal article; Peer reviewed, 2021)Background Traumatic brain injury (TBI) is an important cause of trauma-related mortality and morbidity in Ethiopia. There are significant resource limitations along the entire continuum of care, and little is known about ... -
Prospective Study of Surgery for Traumatic Brain Injury in Addis Ababa, Ethiopia: Trauma Causes, Injury Types, and Clinical Presentation
(Journal article; Peer reviewed, 2021)Background Traumatic brain injury (TBI) is a public health problem in Ethiopia. More knowledge about the epidemiology and neurosurgical management of TBI patients is needed to identify possible focus areas for quality ... -
Protein intake in children and growth and risk of overweight or obesity: A systematic review and meta-analysis
(Journal article; Peer reviewed, 2022)Objectives: The aim of this study was to examine the evidence for an association between the dietary protein intake in children and the growth and risk of overweight or obesity up to 18 years of age in settings relevant ... -
Proteomic analysis of formalin-fixed paraffin-embedded glomeruli suggests depletion of glomerular filtration barrier proteins in two-kidney one-clip hypertensive rats
(Peer reviewed; Journal article, 2014-08-16)Background It is well known that hypertension may cause glomerular damage, but the molecular mechanisms involved are still incompletely understood. Methods In the present study, we used formalin-fixed paraffin-embedded ... -
Proteomic analysis of total cellular proteins of human neutrophils
(Peer reviewed; Journal article, 2009-08-31)Background: Neutrophils are the most abundant leukocytes in peripheral blood and represent one of the most important elements of innate immunity. Recent subcellular proteomic studies have focused on the identification of ... -
Proteomic analysis unveils Gb3-independent alterations and mitochondrial dysfunction in a gla−/− zebrafish model of Fabry disease
(Journal article; Peer reviewed, 2023)Background Fabry disease (FD) is a rare lysosomal storage disorder caused by mutations in the GLA gene, resulting in reduced or lack of α-galactosidase A activity. This results in the accumulation of globotriaosylceramide ... -
Proteomic and histopathological characterisation of sicca subjects and primary Sjögren’s syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers
(Peer reviewed; Journal article, 2019-07-31)Background Mononuclear cell infiltration of exocrine glands, production of Ro/SSA and La/SSB autoantibodies, along with oral and ocular dryness, are characteristic features of primary Sjögren’s syndrome (pSS). Non-SS sicca ... -
Proteomic signature of tubulointerstitial tissue predicts prognosis in IgAN
(Journal article; Peer reviewed, 2022-03-24)Background: IgA nephropathy (IgAN) is associated with a significant risk of progression to kidney failure. Tubular atrophy is an established important risk factor for progressive disease, but few studies have investigated ... -
Protocol for data extraction: how realworld data have been used in the National Institute for Health and Care Excellence appraisals of cancer therapy
(Journal article; Peer reviewed, 2022)Introduction Due to the limitations of relying on randomised controlled trials, the potential benefits of real-world data (RWD) in enriching evidence for health technology assessment (HTA) are highlighted. Despite increased ... -
Proton pump inhibitors in acid-related diseases. Issues in diagnosis, treatment and outcome
(Doctoral thesis, 2013-06-18)Acid-related disease (ARD) is a term used to describe a range of conditions in which acid is involved in the generation of symptoms and/or complications. Two of the most common ARDs are gastro-esophageal reflux disease ... -
PRSS2 remodels the tumor microenvironment via repression of Tsp1 to stimulate tumor growth and progression
(Journal article; Peer reviewed, 2022)The progression of cancer from localized to metastatic disease is the primary cause of morbidity and mortality. The interplay between the tumor and its microenvironment is the key driver in this process of tumor progression. ... -
Psoriasis in Norway: A Prescription-based Registry Study of Incidence and Prevalence
(Journal article; Peer reviewed, 2023)Epidemiological data on psoriasis in Norway are limited. The aim of this study was to provide objective national data on the incidence and prevalence of psoriasis. Patients registered in the Norwegian Prescription Database ... -
Psychiatric Comorbidity, Social Aspects and Quality of Life in a Population-Based Cohort of Expecting Fathers with Epilepsy
(Peer reviewed; Journal article, 2015-12-04)Objectives. To investigate psychiatric disorders, adverse social aspects and quality of life in men with epilepsy during partner’s pregnancy. Method. We used data from the Norwegian Mother and Child Cohort Study, including ... -
Psychiatric disease, adverse social aspects, and quality of life in women and men with epilepsy related to pregnancy
(Doctoral thesis, 2016-11-11)Background: Epilepsy occurs in 0.7-1.3 % of the population and affects both genders and all age groups, including women and men of fertile age. Epilepsy is an important cause of disability with consequences for work ... -
Psychiatric disorders in children with cerebral palsy. Is there a need for mental health screening?
(Doctoral thesis, 2015-06-12)Cerebral palsy (CP) is one of the most prevalent neuro-motor disorders in childhood. Previous studies using mental health questionnaires, had found mental health problems in up to every second child with CP. Peer problems ... -
Psychiatric patients’ attitudes towards being hospitalized: a national multicentre study in Norway
(Journal article; Peer reviewed, 2022-11-21)Background: The aim of the study was to explore patients’ attitudes towards voluntary and involuntary hospitalization in Norway, and predictors for involuntary patients who wanted admission. Methods: A multi-centre study ... -
Quality of clinical management of cardiometabolic risk factors in patients with severe mental illness in a specialist mental health care setting
(Journal article; Peer reviewed, 2022)Purpose Cardiometabolic disease in patients with severe mental illness is a major cause of shortened life expectancy. There is sparse evidence of real-world clinical risk prevention practice. We investigated levels of ... -
Quality of dietary fat and risk of Alzheimer’s disease and dementia in adults aged ≥50 years: a systematic review
(Journal article; Peer reviewed, 2022)Objective: To identify, critically appraise, and synthesize evidence on the effect of quality of dietary fat intake and different classes of fatty acids on the risk of Alzheimer’s disease (AD) and dementia in adults aged ...