• Duodenal administered seal oil for patients with subjective food hypersensitivity: an explorative open pilot study 

      Gregersen, Kine; Lind, Ragna Anne; Valeur, Jørgen; Bjørkkjær, Tormod; Berstad, Arnold; Lied, Gülen Arslan (Peer reviewed; Journal article, 2010-12)
      Short-term duodenal administration of n-3 polyunsaturated fatty acid (PUFA)-rich seal oil may improve gastrointestinal complaints in patients with subjective food hypersensitivity, as well as joint pain in patients with ...
    • Duodenal Chromogranin A Cell Density as a Biomarker for the Diagnosis of Irritable Bowel Syndrome 

      El-Salhy, Magdy; Gilja, Odd Helge; Gundersen, Doris Irene; Hatlebakk, Jan G; Hausken, Trygve (Peer reviewed; Journal article, 2014-06-16)
      Background and Aim. Chromogranin A (CgA) is a common marker for endocrine cells. The density of duodenal CgA cells is reduced in patients with irritable bowel syndrome (IBS). Methods. The present study was undertaken to ...
    • The Dynamics and Prognostic Potential of DNA Methylation Changes at Stem Cell Gene Loci in Women's Cancer 

      Zhuang, Joanna; Jones, Allison; Lee, Shih-Han; Ng, Esther; Fiegl, Heidi; Zikan, Michal; Cibula, David; Sargent, Alexandra; Salvesen, Helga Birgitte; Jacobs, Ian J.; Kitchener, Henry C.; Teschendorff, Andrew E.; Widschwendter, Martin (Peer reviewed; Journal article, 2012-02-09)
      Aberrant DNA methylation is an important cancer hallmark, yet the dynamics of DNA methylation changes in human carcinogenesis remain largely unexplored. Moreover, the role of DNA methylation for prediction of clinical ...
    • Dyslipidemia and rupture risk of intracranial aneurysms—a systematic review 

      Løvik, Katja; Laupsa-Borge, Johnny; Logallo, Nicola; Helland, Christian Andre (Journal article; Peer reviewed, 2021)
      Dyslipidemia is a well-established risk factor for coronary artery disease. However, the effect on cerebral artery disease, and more specifically the rupture risk of intracranial aneurysms, is unclear and has not yet been ...
    • Early aseptic loosening of a mobile-bearing total knee replacement 

      Kutzner, Ines; Halland, Geir; Høl, Paul Johan; Furnes, Ove; Gøthesen, Øystein; Figved, Wender; Ellison, Peter (Peer reviewed; Journal article, 2017)
      Background and purpose - Registry-based studies have reported an increased risk of aseptic tibial loosening for the cemented Low Contact Stress (LCS) total knee replacement compared with other cemented designs; however, ...
    • Early constipation predicts faster dementia onset in Parkinson's disease 

      Camacho, Marta; Macleod, Angus D.; Grødem, Jodi Maple; Evans, Jonathan R.; Breen, David P.; Cummins, G; Wijeyekoon, Ruwani; Greenland, Julia; Alves, Guido Werner; Tysnes, Ole-Bjørn; Lawson, Rachel A.; Barker, Roger A.; Williams-Gray, Caroline H. (Journal article; Peer reviewed, 2021)
      Constipation is a common but not a universal feature in early PD, suggesting that gut involvement is heterogeneous and may be part of a distinct PD subtype with prognostic implications. We analysed data from the Parkinson’s ...
    • Early diagnosis is associated with improved clinical outcomes in benign esophageal perforation: an individual patient data meta‑analysis 

      Vermeulen, Bram D.; van der Leeden, Britt; Ali, Jawad T.; Gudbjartsson, Tomas; Hermansson, Michael; Low, Donald E.; Adler, Douglas G.; Botha, Abraham J.; D’Journo, Xavier B.; Eroglu, Atila; Ferri, Lorenzo E.; Gubler, Christoph; Haveman, Jan Willem; Kaman, Lileswar; Kozarek, Richard A.; Law, Simon; Loske, Gunnar; Lindenmann, Joerg; Park, Jung-Hoon; Richardson, J. David; Salminen, Paulina; Song, Ho-Yong; Søreide, Jon Arne; Spaander, Manon; Tarascio, Jeffrey N.; Tsai, Jon A.; Vanuytsel, Tim; Rosman, Camiel; Siersema, Peter D.; van der Bogt, Ruben D.; Birch, Madeleine; Dubose, Joseph J.; Fox, Sam; Jaklitsch, Michael T.; Kuppusamy, Madhan K.; Persson, Saga; Rice, Robert D.; Smolle, Josef; Smolle-Juettner, Freyja M.; Sudarshan, Monisha; Sutcliffe, Robert P.; Vidarsdottir, Halla; Viste, Asgaut (Journal article; Peer reviewed, 2020)
      Background Time of diagnosis (TOD) of benign esophageal perforation is regarded as an important risk factor for clinical outcome, although convincing evidence is lacking. The aim of this study is to assess whether time ...
    • Early indicators of disease progression in Fabry disease that may indicate the need for disease-specific treatment initiation: Findings from the opinion-based PREDICT-FD modified Delphi consensus initiative 

      Hughes, Derralynn A.; Aguiar, Patricio; Deegan, Patrick B; Ezgu, Fatih; Frustaci, Andrea; Lidove, Olivier; Linhart, Aleš; Lubanda, Jean-Claude; Moon, James C; Nicholls, Kathleen; Niu, Dau-Ming; Nowak, Albina; Ramaswami, Uma; Reisin, Ricardo; Rozenfeld, Paula; Schiffmann, Raphael; Svarstad, Einar; Thomas, Mark; Torra, Roser; Vujkovac, Bojan; Warnock, David G.; West, Michael L; Johnson, Jack; Rolfe, Mark J; Feriozzi, Sandro (Journal article; Peer reviewed, 2020)
      Objectives The PRoposing Early Disease Indicators for Clinical Tracking in Fabry Disease (PREDICT-FD) initiative aimed to reach consensus among a panel of global experts on early indicators of disease progression that may ...
    • Early neurological worsening in acute ischaemic stroke patients 

      Nacu, Aliona; Bringeland, Gerd Haga; Khanevski, Andrej; Thomassen, Lars; Waje-Andreassen, Ulrike; Næss, Halvor (Peer reviewed; Journal article, 2016-01)
      Objectives: Neurological worsening in acute ischaemic stroke patients is common with significant morbidity and mortality. Aims: To determine the factors associated with early neurological worsening within the first 9 h ...
    • Early Parkinson’s Disease. Incidence, clinical features and quality of life in a population-based cohort study. 

      Müller, Bernd (Doctoral thesis, 2014-06-06)
      Background: The prevalence of Parkinson’s Disease (PD) in Norway is about 100/100 000 inhabitants. For planning of health care needs and for research purposes, incidence figures are considered the more valuable information, ...
    • Early substance use cessation improves cognition-10 years outcome in first-episode psychosis patients 

      Weibell, Melissa Anne E; Johannessen, Jan Olav; Auestad, Bjørn Henrik; Bramness, Jørgen Gustav; Brønnick, Kolbjørn Kallesten; Haahr, Ulrik; Joa, Inge; Larsen, Tor Ketil; Melle, Ingrid; Ilner, Stein E. Opjordsmoen; Rund, Bjørn Rishovd; Røssberg, Jan Ivar; Simonsen, Erik; Vaglum, Per; Stain, Helen J.; Friis, Svein; Hegelstad, Wenche (Peer reviewed; Journal article, 2019-07-12)
      Background: Cognitive impairment may be a risk factor for, as well as a consequence of, psychosis. Non-remitting symptoms, premorbid functioning, level of education, and socioeconomic background are known correlates. A ...
    • Economic aspects of Parkinson’s disease 

      Vossius, Corinna (Doctoral thesis, 2009-11-13)
      Background: Next to Alzheimer’s disease, Parkinson’s disease (PD) is the second most neurodegenerative disease. As the population structure in the industrialized and industrializing countries is changing, an increasing ...
    • The economic impact of multiple sclerosis to the patients and their families in Norway 

      Svendsen, Bjørn; Grytten, Nina; Bø, Lars; Aarseth, Hallvard Gilje; Smedal, Tori; Myhr, Kjell-Morten (Peer reviewed; Journal article, 2018-12)
      Background: Multiple sclerosis (MS) imposes high economic costs on society, but the patients and their families have to bear some of these costs. Objective: We aimed to estimate the magnitude of these economic costs in ...
    • An economic model to evaluate cost-effectiveness of computer assisted knee replacement surgery in Norway 

      Gøthesen, Øystein Johannes; Slover, James; Havelin, Leif Ivar; Askildsen, Jan Erik; Malchau, Henrik; Furnes, Ove (Peer reviewed; Journal article, 2013-07-06)
      Background: The use of Computer Assisted Surgery (CAS) for knee replacements is intended to improve the alignment of knee prostheses in order to reduce the number of revision operations. Is the cost effectiveness of computer ...
    • Editorial: facts, figures and the future 

      Søreide, Kjetil (Peer reviewed; Journal article, 2015-01-09)
    • Efect of high intake of cod or salmon on serum total neopterin concentration: a randomised clinical trial 

      Helland, Anita; Bratlie, Marianne; Hagen, Ingrid V.; Midttun, Øivind; Sveier, Harald; Mellgren, Gunnar; Ueland, Per Magne; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2021)
      Purpose Primarily, to investigate the effect of high intake of cod (lean fish) or salmon (fatty fish) on serum concentration of total neopterin, a marker of cellular immune activation that is associated with cardiovascular ...
    • Effect of a cod protein hydrolysate on postprandial glucose metabolism in healthy subjects: A double-blind cross-over trial 

      Dale, Hanna Fjeldheim; Jensen, Caroline; Hausken, Trygve; Lied, Einar; Hatlebakk, Jan Gunnar; Brønstad, Ingeborg; Hoff, Dag Arne Lihaug; Lied, Gülen Arslan (Peer reviewed; Journal article, 2018)
      The increased prevalence of lifestyle diseases, such as the metabolic syndrome and type 2 diabetes mellitus (T2DM), calls for more knowledge on dietary treatments targeting the specific metabolic pathways involved in these ...
    • The effect of a low FODMAP diet in addition to a gluten free diet on symptoms and quality of life in patients with coeliac disease and IBS-like symptoms: A randomized, controlled clinical study 

      Nuland, Kamilla (Master thesis, 2016-05-17)
      Around 20-30% of coeliac disease patients have IBS-like symptoms. The low FODMAP diet (low in fermentable oligo-, di-, monosaccharides and polyols) is used as treatment for irritable bowel syndrome (IBS) to reduce ...
    • Effect of Ascaris Lumbricoides specific IgE ontuberculin skin test responses in children in a high-burdensetting: a cross-sectional community-based study 

      van Soelen, Nelda; Mandalakas, Anna M; Kirchner, H Lester; Walzl, Gerhard; Grewal, Harleen M. S.; Jacobsen, Marc; Hesseling, Anneke C. (Peer reviewed; Journal article, 2012-09-11)
      Background: M.tuberculosis (M.tb) is associated with enhanced T helper cell type 1 (Th1) immune responses while helminth infection is associated with T helper cell type 2 (Th2) immune responses. Our aim was to investigate ...
    • Effect of cod residual protein supplementation on markers of glucose regulation in lean adults: A randomized double-blind study 

      Vildmyren, Iselin; Halstensen, Alfred; McCann, Adrian; Midttun, Øivind; Ueland, Per Magne; Oterhals, Åge; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2020)
      Large quantities of protein-rich cod residuals, which are currently discarded, could be utilized for human consumption. Although fish fillet intake is related to beneficial health effects, little is known about the potential ...