Browsing Department of Clinical Medicine by Title
Now showing items 756-775 of 1495
-
Incidence, pattern and mechanisms of injuries and fractures in children under two years of age
(Journal article; Peer reviewed, 2021)Background Fractures in children under 2 years of age are rare, and little has been published on their mechanisms. We aimed at examining the incidence, mechanisms, pattern and fracture characteristics in a large, ... -
Increased chromogranin A cell density in the large intestine of patients with irritable bowel syndrome after receiving dietary guidance
(Peer reviewed; Journal article, 2015)The large intestine contains five types of endocrine cells that regulate its functions by sensing its luminal contents and releasing specific hormones. Chromogranin A (CgA) is a common marker for the gastrointestinal ... -
Increased incidence of postoperative infections during prophylaxis with cephalothin compared to doxycycline in intestinal surgery
(Peer reviewed; Journal article, 2009-12-07)Background: The antibiotics used for prophylaxis during surgery may influence the rate of surgical site infections. Tetracyclines are attractive having a long half-life and few side effects when used in a single dose ... -
Increased risk of hospitalisation and intensive care admission associated with reported cases of SARS-CoV-2 variants B.1.1.7 and B.1.351 in Norway, December 2020-May 2021
(Journal article; Peer reviewed, 2021)Introduction Since their emergence, SARS-CoV-2 variants of concern (VOC) B.1.1.7 and B.1.351 have spread worldwide. We estimated the risk of hospitalisation and admission to an intensive care unit (ICU) for infections ... -
Increased risk of revision for infection in rheumatoid arthritis patients with total hip replacements. A study of 390,671 primary arthroplasties from the Nordic Arthroplasty Register Association
(Peer reviewed; Journal article, 2015)Background and purpose — Medical treatment of rheumatoid arthritis (RA) has changed dramatically over the last 15 years, including immune modulation. We investigated the risk of revision for infection after primary total ... -
Increased risk of revision of cementless stemmed total hip arthroplasty with metal-on-metal bearingsData from the Nordic Arthroplasty Register Association
(Peer reviewed; Journal article, 2015)Background and purpose — Data from the national joint registries in Australia and England and Wales have revealed inferior medium-term survivorship for metal-on-metal (MoM) total hip arthroplasty (THA) than for ... -
Increasing but levelling out risk of revision due to infection after total hip arthroplasty: a study on 108,854 primary THAs in the Norwegian Arthroplasty Register from 2005 to 2019
(Journal article; Peer reviewed, 2020)Background and purpose — Focus on prevention, surveillance, and treatment of infection after total hip arthroplasty (THA) in the last decade has resulted in new knowledge and guidelines. Previous publications have suggested ... -
Increasing risk of prosthetic joint infection after total hip arthroplasty. 2,778 revisions due to infection after 432,168 primary THAs in the Nordic Arthroplasty Register Association (NARA)
(Peer reviewed; Journal article, 2012-10)Background and purpose: The risk of revision due to infection after primary total hip arthroplasty (THA) has been reported to be increasing in Norway. We investigated whether this increase is a common feature in the Nordic ... -
Increasing risk of revision due to deep infection after hip arthroplasty. A study on 97,344 primary total hip replacements in the Norwegian Arthroplasty Register from 1987 to 2007
(Peer reviewed; Journal article, 2009-12)Background and purpose: Over the decades, improvements in surgery and perioperative routines have reduced the incidence of deep infections after total hip arthroplasty (THA). There is, however, some evidence to suggest ... -
Increasing the Dose and/or Repeating Faecal Microbiota Transplantation (FMT) Increases the Response in Patients with Irritable Bowel Syndrome (IBS)
(Peer reviewed; Journal article, 2019-06-24)Background: Faecal microbiome transplantation (FMT) appears to be an effective method for treating irritable bowel syndrome (IBS) patients. However, it is not clear if a high transplant dose and/or repeating FMT are/is ... -
An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment
(Peer reviewed; Journal article, 2019)How mixtures of immune cells associate with cancer cell phenotype and affect pathogenesis is still unclear. In 15 breast cancer gene expression datasets, we invariably identify three clusters of patients with gradual levels ... -
Individual Variability in Reaction Time and Prediction of Clinical Response to Methylphenidate in Adult ADHD: A Prospective Open Label Study Using Conners’ Continuous Performance Test II
(Peer reviewed; Journal article, 2019)Objective: The aim of this study was to examine whether reaction time parameters in adult patients with ADHD could predict their response to methylphenidate (MPH). Method: Previously unmedicated patients (N = 123) were ... -
Infant growth in the KwaZulu-Natal province, South Africa: Results from the KwaZulu-Natal initiative for breastfeeding support (KIBS) survey II at 13-15 weeks and 6 months of age
(Master thesis, 2018-06-22)Background: Today, 155 million children under the age of five years are stunted in the world, 52 million are wasted, while 41 million are overweight. When these conditions exist at the same time, within an individual, ... -
Infected total hip arthroplasty - Bacteriology and the role of operating room ventilation in the reduction of postoperative infection
(Doctoral thesis, 2020-10-09)Each year approximately 7,000 patients receive a total hip arthroplasty (THA) in Norway. The most common indication is osteoarthritis and most patients experience substantial pain relief postoperatively. A rare but much ... -
Infection after primary hip arthroplasty. A comparison of 3 Norwegian health registers
(Peer reviewed; Journal article, 2011-12)Background and purpose: The aim of the present study was to assess incidence of and risk factors for infection after hip arthroplasty in data from 3 national health registries. We investigated differences in risk patterns ... -
Infection after primary hip arthroplasty. Epidemiology, time trends and risk factors in data from national health registers. The Norwegian Arthroplasty Register
(Doctoral thesis; Peer reviewed, 2013-02-08)Every year, more than 10,000 Norwegians undergo hip replacement (7,360 THAs and 3,214 HAs in 2011). This may be due to osteoarthritis (OA), inflammatory joint disease, fractures, fracture sequelae, aseptic femoral head ... -
Inflammation markers in multiple sclerosis: CXCL16 reflects and may also predict disease activity
(Peer reviewed; Journal article, 2013-09-19)Background. Serum markers of inflammation are candidate biomarkers in multiple sclerosis (MS). ω-3 fatty acids are suggested to have anti-inflammatory properties that might be beneficial in MS. We aimed to explore the ... -
Inflammatory Stratification in Primary Sjögren’s Syndrome Reveals Novel Immune Cell Alterations in Patients’ Minor Salivary Glands
(Journal article; Peer reviewed, 2021)There is a critical need to deconvolute the heterogeneity displayed by the minor salivary glands of primary Sjögren’s syndrome (pSS) patients. This is challenging primarily because the disease etiology remains unknown. The ... -
Inflammatory tissue reactions around aseptically loose cemented hip prostheses: A retrieval study of the Spectron EF stem with Reflection All-Poly acetabular cup
(Journal article; Peer reviewed, 2022)The cemented Spectron EF stem in combination with the cemented non-crosslinked Reflection All-Poly cup showed a high rate of mid-term aseptic loosening. However, the failure mechanisms are not fully known. We assessed the ... -
Influence of hospital procedure volume on the risk of revision in knee arthroplasty surgery
(Doctoral thesis, 2016-10-07)The knee is a complex joint consisting of three anatomically and kinematically different compartments; the medial, the lateral and the patellofemoral compartment. When developing painful and disabling osteoarthritis (OA), ...