Blar i Department of Clinical Medicine på tittel
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Integrated Genomic Analysis of the 8q24 Amplification in Endometrial Cancers Identifies ATAD2 as Essential to MYC-Dependent Cancers
(Peer reviewed; Journal article, 2013-02-05)Chromosome 8q24 is the most commonly amplified region across multiple cancer types, and the typical length of the amplification suggests that it may target additional genes to MYC. To explore the roles of the genes most ... -
Integrin a11 is overexpressed by tumour stroma of head and neck squamous cell carcinoma and correlates positively with alpha smooth muscle actin expression
(Peer reviewed; Journal article, 2017-04)BACKGROUND: Cancer-associated fibroblasts (CAFs) were shown to be important for tumour progression in head and neck squamous cell carcinomas (HNSCCs). Their heterogeneity and lack of specific markers is increasingly ... -
Integrin α11β1 is expressed in breast cancer stroma and associates with aggressive tumor phenotypes
(Peer reviewed; Journal article, 2020)Cancer‐associated fibroblasts are essential modifiers of the tumor microenvironment. The collagen‐binding integrin α11β1 has been proposed to be upregulated in a pro‐tumorigenic subtype of cancer‐associated fibroblasts. ... -
Inter-hospital transfer: the crux of the trauma system, a curse for trauma registries
(Journal article, 2010-03-16)The inter-hospital transfer of patients is crucial to a well functioning trauma system, and the transfer process may serve as a quality indicator for regional trauma care. However, the assessment of the transfer process ... -
Interaction between ingested nutrients and gut endocrine cells in patients with irritable bowel syndrome (Review)
(Peer reviewed; Journal article, 2014-08)Several endocrine cell abnormalities have been reported in different segments of the gastrointestinal tract of patients with irritable bowel syndrome (IBS). These cells have specialized microvilli that project into the ... -
Interactions between Fusobacterium nucleatum and Primary Human Oral Cells: In Vitro Studies in Monolayer and Organotypic Culture Models
(Doctoral thesis, 2012-06-21)F. nucleatum is a Gram-negative bacterium, member of normal flora in the oral cavity, which has a major role in the formation of the subgingival biofilm. The adhesins expressed on the cell wall outer membrane confer F. ... -
Interdisciplinary Approaches Suggested for Children With Multiple Hospital Referrals Presenting With Non-specific Conditions
(Journal article; Peer reviewed, 2021)Aims: To describe the care patterns of patients with repeated referrals to both mental and somatic specialist healthcare, and to study their diagnostic processes. Methods: In a previous register study patients aged 6–12 ... -
Interictal epileptiform discharges vary across age groups
(Journal article; Peer reviewed, 2020-01)Objective To investigate whether the occurrence and morphology of interictal epileptiform discharges (IEDs) in scalp-EEG change by age. Methods 10,547 patients who had a standard or sleep deprived EEG recording reported ... -
Internalizing Symptom Profiles Among Youth in Foster Care: A Comparison Study
(Journal article; Peer reviewed, 2021)Background: A high prevalence of anxiety and depression is found among youth in foster care. There is limited knowledge on the anxiety and depression symptom profiles of youth in foster care. We examined latent profiles ... -
International variation in distribution of ASA class in patients undergoing total hip arthroplasty and its influence on mortality: data from an international consortium of arthroplasty registries
(Journal article; Peer reviewed, 2021)Background and purpose — A challenge comparing outcomes from total hip arthroplasty between countries is variation in preoperative characteristics, particularly comorbidity. Therefore, we investigated between-country ... -
Interstitial Fluid Colloid Osmotic Pressure in Healthy Children
(Peer reviewed; Journal article, 2015-04-08)Objective: The colloid osmotic pressure (COP) of plasma and interstitial fluid play important roles in transvascular fluid exchange. COP values for monitoring fluid balance in healthy and sick children have not been ... -
Interventions on arterial pressure and perfusion flow rate during cardiopulmonary bypass : effects on global fluid shifts, cerebral metabolic and structural markers in a porcine model
(Doctoral thesis, 2008-01-18)Global and regional organ perfusion during cardiopulmonary bypass (CPB) depends on hemodynamic parameters as mean arterial pressure (MAP) and perfusion flow rate. These parameters may also exert influence on the load of ... -
Intestinal barrier integrity in anorexia nervosa (a pilot study)
(Journal article; Peer reviewed, 2022)Objective There is no conclusive evidence for involvement of intestinal barrier alteration in the etiology of anorexia nervosa (AN). The aims of this pilot study were to identify serum markers of intestinal barrier integrity ... -
Intestinal Ultrasound to Assess Disease Activity in Ulcerative Colitis: Development of a novel UC-Ultrasound Index
(Journal article; Peer reviewed, 2021)Introduction: Intestinal ultrasound [IUS] is useful to assess inflammation in ulcerative colitis [UC] patients. We aimed to develop an ultrasonographic activity index using endoscopy as the reference standard. Methods: ... -
Intracerebral Hemorrhage In Southern Norway. A study of incidence and outcome
(Doctoral thesis, 2013-11-29)Aims: We aimed to assess the incidence and baseline characteristics of first ever intracerebral hemorrhage (ICH) in Southern Norway leading to hospitalization, mortality rates after ICH and factors associated with 30-day ... -
Intracranial arachnoid cysts: impairment of higher cognitive functions and postoperative improvement
(Peer reviewed; Journal article, 2013-08-28)Background Intracranial arachnoid cysts have been shown to yield cognitive impairment over a range of basic mental functions, and these functions normalize after surgical cyst decompression. We wanted to investigate whether ... -
Intracranial Atherosclerosis. An ultrasound study
(Doctoral thesis, 2012-12-07) -
Intramedullary Nails Result in More Reoperations Than Sliding Hip Screws in Two-part Intertrochanteric Fractures
(Peer reviewed; Journal article, 2013-04-01)Background Sliding hip screws (SHSs) and intramedullary (IM) nails are well-documented implants for simple two-part intertrochanteric fractures; however, there is no consensus regarding which type of implant is better. ... -
Intramural gastric pseudocyst: A case report and a comprehensive literature review
(Peer reviewed; Journal article, 2017)Rationale: Intramural pseudocyst, although first reported several decades ago, is a rare entity. Scientific knowledge regarding its clinical management is sparse. Patient concerns: We present three cases to show the diverse ... -
Intraoperative anaphylaxis to gelatin-basedhemostatic agents: a case report
(Peer reviewed; Journal article, 2019)Surgiflo Haemostatic Matrix is an absorbable gelatin matrix hemostatic material that has been widely used in various surgical operations to assist hemostasis. Nonetheless, as biologically active agents (contains porcine ...