Blar i Department of Clinical Medicine på tittel
Viser treff 831-850 av 2045
-
Gastrointestinal Ultrasound Can Predict Endoscopic Activity in Crohn’s Disease
(Journal article; Peer reviewed, 2020-04-24)Purpose To explore the ability of gastrointestinal ultrasound (GIUS) to separate patients in endoscopic remission from patients with active disease in a heterogeneous hospital cohort with Crohn’s disease (CD). Materials ... -
Gastrointestinal Ultrasound in Functional Disorders of the Gastrointestinal Tract - EFSUMB Consensus Statement
(Journal article; Peer reviewed, 2021)Abdominal ultrasonography and intestinal ultrasonography are widely used as first diagnostic tools for investigating patients with abdominal symptoms, mainly for excluding organic diseases. However, gastrointestinal ... -
Gastroparesis Symptoms Associated with Intestinal Hypomotility: An Explorative Study Using Wireless Motility Capsule
(Journal article; Peer reviewed, 2021)Objective: Gastric emptying measurements are mandatory in gastroparesis diagnostics, but the association between delayed emptying and symptoms is questionable. It is imperative to find biomarkers better correlated to symptom ... -
GBA and APOE Impact Cognitive Decline in Parkinson's Disease: A 10-Year Population-Based Study
(Journal article; Peer reviewed, 2022)Background: Common genetic variance in apolipoprotein E (APOE), β-glucocerebrosidase (GBA), microtubule-associated protein tau (MAPT), and α-synuclein (SNCA) has been linked to cognitive decline in Parkinson's disease (PD), ... -
GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study
(Peer reviewed; Journal article, 2019-05-07)Dementia with Lewy Bodies (DLB) is a common neurodegenerative disorder with poor prognosis and mainly unknown pathophysiology. Heritability estimates exceed 30% but few genetic risk variants have been identified. Here we ... -
GBA2 mutations cause a Marinesco-Sjogren-like syndrome: Genetic and biochemical studies
(Peer reviewed; Journal article, 2017-01-04)Background: With the advent new sequencing technologies, we now have the tools to understand the phenotypic diversity and the common occurrence of phenocopies. We used these techniques to investigate two Norwegian families ... -
Gender Differences in Kidney Stone Disease (KSD): Findings from a Systematic Review
(Journal article; Peer reviewed, 2021)Purpose of review: The prevalence of kidney stones is rising and historically carries a preponderance for males. However, recent evidence has questioned whether this gender gap is closing. The aim of this systematic review ... -
Gene expression alterations in salivary gland epithelia of Sjögren’s syndrome patients are associated with clinical and histopathological manifestations
(Journal article; Peer reviewed, 2021)Sjögren’s syndrome (SS) is a complex autoimmune disease associated with lymphocytic infiltration and secretory dysfunction of salivary and lacrimal glands. Although the etiology of SS remains unclear, evidence suggests ... -
Gene Expression Analysis in gla-Mutant Zebrafish Reveals Enhanced Ca2+ Signaling Similar to Fabry Disease
(Journal article; Peer reviewed, 2022)Fabry disease (FD) is an X-linked inborn metabolic disorder due to partial or complete lysosomal α-galactosidase A deficiency. FD is characterized by progressive renal insufficiency and cardio- and cerebrovascular involvement. ... -
Gene expression in the rat brain: High similarity but unique differences between frontomedial-, temporal- and occipital cortex
(Peer reviewed; Journal article, 2011-01-26)Background: The six-layered neocortex of the mammalian brain may appear largely homologous, but is in reality a modular structure of anatomically and functionally distinct areas. However, global gene expression seems to ... -
Gene expression profiles in rat brain disclose CNS signature genes and regional patterns of functional specialisation
(Peer reviewed; Journal article, 2007-04-04)Background: The mammalian brain is divided into distinct regions with structural and neurophysiological differences. As a result, gene expression is likely to vary between regions in relation to their cellular composition ... -
Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains
(Peer reviewed; Journal article, 2019-07-15)About 80% of colorectal cancers (CRCs) have chromosomal instability, which is an integral part of aggressive malignancy development, but the importance of specific copy number aberrations (CNAs) in modulating gene expression, ... -
Gene expression profiling of meningiomas: current status after a decade of microarray-based transcriptomic studies
(Peer reviewed; Journal article, 2011-01-14)Purpose This article provides a review of the transcriptomic expression profiling studies that have been performed on meningiomas so far. We discuss some future prospects and challenges ahead in the field of gene expression ... -
Gene signatures and prognostic factors in endometrial cancer. A study with special focus on vascular invasion
(Doctoral thesis, 2011-04-15) -
Gene-Based Analysis of Regionally Enriched Cortical Genes in GWAS Data Sets of Cognitive Traits and Psychiatric Disorders
(Peer reviewed; Journal article, 2012-02-22)Background: Despite its estimated high heritability, the genetic architecture leading to differences in cognitive performance remains poorly understood. Different cortical regions play important roles in normal cognitive ... -
General practitioners' opinions on how to improve treatment of mental disorders in primary health care. Interviews with one hundred Norwegian general practitioners
(Peer reviewed; Journal article, 2010-02-09)Background: Improvements in treatment of mental disorders are repeatedly called for. General practitioners (GPs) are responsible for the majority of treatment of mental disorders. Consequently, we interviewed GPs about ... -
Generation of a stepwise prostate carcinogenesis model. A study of epithelial to mesenchymal transition and malignant transformation of prostate primary epithelial cells
(Doctoral thesis, 2013-05-29)Despite progress in recent years, prostate cancer continues to be one of the most prevalent causes of cancer-related mortality and morbidity in men in Western countries. A major clinical challenge of prostate cancer therapy ... -
Generic Quality of Life in persons With Hearing Loss: A Systematic Litterature Review
(Peer reviewed; Journal article, 2018-01-22)Background: To the best of our knowledge, no empirically based consensus has been reached as to if, and to what extent, persons with hearing loss (HL) have reduced generic Quality of life (QoL). There seems to be limited ... -
Genes of cell-cell interactions, chemotherapy detoxification and apoptosis are induced during chemotherapy of acute myeloid leukemia
(Peer reviewed; Journal article, 2009-03-05)Background: The molecular changes in vivo in acute myeloid leukemia cells early after start of conventional genotoxic chemotherapy are incompletely understood, and it is not known if early molecular modulations reflect ... -
Genetic and cellular studies of carboxyl-ester lipase (CEL), a protein involved in exocrine and endocrine pancreatic disease
(Doctoral thesis, 2018-09-13)Carboxyl-ester lipase (CEL) is a digestive enzyme mainly expressed in pancreatic acinar cells, from which it is secreted into the duodenum as a component of pancreatic juice. Mutations in the human CEL gene have been linked ...