Browsing Department of Clinical Medicine by Title
Now showing items 1375-1394 of 1484
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Terminal digit preference: a source of measurement error in breast cancer diameter reporting
(Peer reviewed; Journal article, 2019)Objectives: Women diagnosed with breast cancer are offered treatment and therapy based on tumor characteristics, including tumor diameter. There is scarce knowledge whether tumor diameter is accurately reported, or whether ... -
Therapeutic Hypothermia after Out-of-Hospital Cardiac Arrest - implementation and clinical management
(Doctoral thesis, 2012-11-02)Background: With the publication of two randomized controlled trials (RCTs) in 2002, therapeutic hypothermia (TH) was re-introduced in postresuscitation care of comatose out-of-hospital cardiac arrest (OHCA) patients. Many ... -
They know! - do they? A qualitative study of residents and relatives views on advance care planning, end-of-life care, and decision-making in nursing homes.
(Peer reviewed; Journal article, 2015)Background: Residents living in long-term care facilities are a vulnerable population. For many residents, a nursing home is their place of death. Palliative care and end-of-life decisions are important components of their ... -
Thromboprophylaxis in primary shoulder arthroplasty does not seem to prevent death: a report from the Norwegian Arthroplasty Register 2005–2018
(Journal article; Peer reviewed, 2021)Background and purpose — There is still no consensus on whether to use thromboprophylaxis as a standard treatment in shoulder replacement surgery. We investigated the use of thromboprophylaxis reported to the Norwegian ... -
Thrombosis is not a marker of bridging vein rupture in infants with alleged abusive head trauma
(Journal article; Peer reviewed, 2021)Aim Thrombosis of bridging veins has been suggested to be a marker of bridging vein rupture, and thus AHT, in infants with subdural haematoma. Methods This is a non-systematic review based on Pubmed search, secondary ... -
Time course of cerebrovascular reactivity in patients treated for unruptured intracranial aneurysms: A one-year transcranial Doppler and acetazolamide follow-up study
(Peer reviewed; Journal article, 2018-04-26)Background. Cerebrovascular reactivity (CVR) is ofen impaired in the early phase afer aneurysmal subarachnoid hemorrhage. Tere is, however, little knowledge about the time course of CVR in patients treated for unruptured ... -
Time trends in the incidence and prevalence of multiple sclerosis in Norway during eight decades
(Peer reviewed; Journal article, 2015-06-05)Norway has been subjected to numerous epidemiological investigations on the prevalence and incidence of multiple sclerosis (MS), dating back to 1935. The objective of this study was to review the studies on the prevalence ... -
The timing of environmental risk factors and prodromal signs of multiple sclerosis
(Doctoral thesis, 2017-12-18)Background: Multiple sclerosis (MS) is a chronic demyelinating disorder of the central nervous system that can lead to severe disability. It is a complex disease likely caused by genetic and environmental factors combined. ... -
Timing of hip hemiarthroplasty and the influence on prosthetic joint infection
(Journal article; Peer reviewed, 2020-03-12)Introduction Previous research suggested that patients have increased risk of infection with increased time from presentation with a femoral neck fracture to treatment with a hip hemiarthroplasty (HHA). The purpose of ... -
Timing of use of cod liver oil, a vitamin D source, and multiple sclerosis risk: The EnvIMS study.
(Peer reviewed; Journal article, 2015)Background: Low vitamin D levels have been associated with an increased risk of multiple sclerosis (MS), although it remains unknown whether this relationship varies by age. Objective: The objective of this paper is to ... -
Tissue and imaging biomarkers for hypoxia predict poor outcome in endometrial cancer
(Peer reviewed; Journal article, 2016-09-13)Hypoxia is frequent in solid tumors and linked to aggressive phenotypes and therapy resistance. We explored expression patterns of the proposed hypoxia marker HIF-1α in endometrial cancer (EC) and investigate whether ... -
The top five research priorities in physician-provided pre-hospital critical care: a consensus report from a European research collaboration
(Peer reviewed; Journal article, 2011-10-13)Background: Physician-manned emergency medical teams supplement other emergency medical services in some countries. These teams are often selectively deployed to patients who are considered likely to require critical care ... -
Total drug treatment and comorbidity in myasthenia gravis: a population-based cohort study
(Peer reviewed; Journal article, 2014-04-09)Background and purpose: Comorbidity in myasthenia gravis (MG) is important for diagnosis, treatment and prognosis. Disease complexity was assessed by examining total drug treatment, immune therapy and comorbidity in a ... -
Total hip arthroplasties in the Dutch Arthroplasty Register (LROI) and the Nordic Arthroplasty Register Association (NARA): comparison of patient and procedure characteristics in 475,685 cases
(Journal article; Peer reviewed, 2021)Background and purpose — Collaborations between arthroplasty registries are important in order to create the possibility of detecting inferior implants early and improve our understanding of differences between nations in ... -
Total hip replacement in young adults with hip dysplasia. Age at diagnosis, previous treatment, quality of life, and validation of diagnoses reported to the Norwegian Arthroplasty Register between 1987 and 2007
(Peer reviewed; Journal article, 2011-04)Background and purpose: Dysplasia of the hip increases the risk of secondary degenerative change and subsequent total hip replacement. Here we report on age at diagnosis of dysplasia, previous treatment, and quality of ... -
Tracing the HIV-1 subtype B mobility in Europe: a phylogeographic approach
(Peer reviewed; Journal article, 2009-05-20)Background: The prevalence and the origin of HIV-1 subtype B, the most prevalent circulating clade among the long-term residents in Europe, have been studied extensively. However the spatial diffusion of the epidemic from ... -
Trajectories of psychiatric disorders in a cohort of children with cerebral palsy across four years
(Journal article; Peer reviewed, 2021)Background: Risk of psychiatric disorders has been reported for children and adolescents with cerebral palsy (CP) at different ages, however little is known regarding the long-term trajectories of these disorders. Objective: ... -
Transcriptome sequencing (RNAseq) enables utilization of formalin-fixed, paraffin-embedded biopsies with clear cell renal cell carcinoma for exploration of disease biology and biomarker development
(Peer reviewed; Journal article, 2016-02-22)Formalin-fixed, paraffin-embedded (FFPE) tissues are an underused resource for molecular analyses. This proof of concept study aimed to compare RNAseq results from FFPE biopsies with the corresponding RNAlater® (Qiagen, ... -
Transfusion requirements in septic shock (TRISS) trial - comparing the effects and safety of liberal versus restrictive red blood cell transfusion in septic shock patients in the ICU: protocol for a randomised controlled trial
(Peer reviewed; Journal article, 2013-05-23)Background: Transfusion of red blood cells (RBC) is recommended in septic shock and the majority of these patients receive RBC transfusion in the intensive care unit (ICU). However, benefit and harm of RBCs have not been ... -
Transgenerational and intergenerational epigenetic inheritance in allergic diseases
(Peer reviewed; Journal article, 2018-09)It has become clear that early life (including in utero exposures) is a key window of vulnerability during which environmental exposures can alter developmental trajectories and initiate allergic disease development. ...