Blar i Department of Clinical Medicine på tittel

Viser treff 781-800 av 2043

    • Ferroptosis Holds Novel Promise in Treatment of Cancer Mediated by Non-coding RNAs 

      Zhi, Yuan; Gao, Ling; Wang, Baisheng; Ren, Wenhao; Liang, Xiao; Zhi, Ke-Qian (Journal article; Peer reviewed, 2021)
      Ferroptosis is a newly identified form of regulated cell death that is associated with iron metabolism and oxidative stress. As a physiological mechanism, ferroptosis selectively removes cancer cells by regulating the ...

    • Fetal Liver Blood Flow Distribution: Role in Human Developmental Strategy to Prioritize Fat Deposition versus Brain Development 

      Godfrey, Keith M.; Haugen, Guttorm; Kiserud, Torvid; Inskip, Hazel M.; Cooper, Cyrus; The Southampton Women's Survey Study Group (Peer reviewed; Journal article, 2012-08-22)
      Among primates, human neonates have the largest brains but also the highest proportion of body fat. If placental nutrient supply is limited, the fetus faces a dilemma: should resources be allocated to brain growth, or to ...

    • Fetal splanchnic arteries. A longitudinal study and hemodynamic relations to common Doppler parameters 

      Ebbing, Cathrine (Doctoral thesis, 2008-05-30)
      Although the arterial splanchnic circulation is known to be dynamic and of clinical interest during postnatal life, little is known about its prenatal development and function. We hypothesised that current ultrasound ...

    • Fever-related ataxia: a case report of CAPOS syndrome 

      Stenshorne, Ida; Rasmussen, Magnhild; Salvanos, Panagiotis; Tallaksen, Chantal; Bindoff, Laurence; Koht, Jeanette (Journal article; Peer reviewed, 2019)
      Background: CAPOS (Cerebellar ataxia, Areflexia, Pes cavus, Optic atrophy and Sensorineural hearing loss) syndrome is caused by the heterozygous mutation, c.2452G > A, in the ATP1A3 gene. Other mutations in this gene ...

    • FGD5 amplification in breast cancer patients is associated with tumor proliferation and a poorer prognosis 

      Valla, Marit; Engstrøm, Monica J; Ytterhus, Borgny; Hansen, Åse Kristin Skain; Akslen, Lars A.; Vatten, Lars Johan; Opdahl, Signe; Bofin, Anna M. (Peer reviewed; Journal article, 2017-04)
      Purpose: Proliferation is a hallmark of cancer. Using a combined genomic approach, FGD5 amplification has been identified as a driver of proliferation in Luminal breast cancer. We aimed to describe FGD5 copy number change ...

    • Fibulin-2 expression associates with vascular invasion and patient survival in breast cancer 

      Klingen, Tor Audun; Chen, Ying; Aas, Hans; Wik, Elisabeth; Akslen, Lars Andreas (Journal article; Peer reviewed, 2021)
      Stromal elastosis is related to good prognosis in breast cancer and fibulin-2 helps to stabilize elastic fibers in basement membranes. Here, we examined the level of perivascular fibulin-2 expression in relation to elastosis ...

    • “Finding stability”. Experienced and measured function in patients undergoing surgery for patellar instability 

      Hysing-Dahl, Trine (Doctoral thesis, 2023-12-15)
      Bakgrunn: Vurdering av knefunksjon er helt sentralt for diagnostikk, behandling og oppfølging av pasienter med ulike kneledds lidelser. Derfor er det behov for gyldige og pålitelige måleverktøy, inkludert pasientrapporterte ...

    • Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions 

      Barrett, Jennifer H.; Taylor, John C.; Bright, C; Harland, Mark; Dunning, Alison M; Akslen, Lars A.; Andresen, Per Arne; Avril, Marie-Francoise; Azizi, Esther; Scarra, Giovanna Bianchi; Brossard, Myriam; Brown, Kevin M.; Debniak, Tadeusz; Elder, David E.; Friedman, Eitan; Ghiorzo, Paola; Gillanders, Elizabeth M.; Gruis, Nelleke A.; Hansson, Johan; Helsing, Per; Hočevar, Marko; Höiom, Veronica; Ingvar, Christian; Landi, Maria Teresa; Lang, Julie L.; Lathrop, G. Mark; Lubinski, Jan; Mackie, Rona M.; Molven, Anders; Novakovic, Srdjan; Olsson, Håkan; Puig, Susana; Puig-Butille, Joan Anton; van der Stoep, Nienke; van Doorn, Remco; van Workum, Wilberg; Goldstein, Alisa M.; Kanetsky, Peter A.; Pharoah, Paul D.P.; Demenais, Florence; Hayward, Nicholas K.; Bishop, Julia A. Newton; Bishop, D. Timothy; Iles, Mark M. (Peer reviewed; Journal article, 2015-08-14)
      At least 17 genomic regions are established as harboring melanoma susceptibility variants, in most instances with genome-wide levels of significance and replication in independent samples. Based on genome-wide single ...

    • Fine needle aspirates of kidneys: A promising tool for RNA sequencing in native and transplanted kidneys 

      Eikrem, Øystein Solberg; Walther, Tedd Christian; Flatberg, Arnar; Beisvag, Vidar; Strauss, Philipp; Farstad, Magnus; Beisland, Christian; Koch, Even; Mueller, Thomas F.; Marti, Hans-Peter (Peer reviewed; Journal article, 2018-09-18)
      Background: Transcriptome analysis is emerging as emerging as a promising tool to enhance precision of diagnosis and monitoring in solid organ transplantation. Clinical progress has however been hampered by the current ...

    • Fingolimod does not enhance cerebellar remyelination in the cuprizone model 

      Alme, Maria Nordheim; Nystad, Agnes Elisabeth; Bø, Lars; Myhr, Kjell-Morten; Vedeler, Christian A.; Wergeland, Stig; Torkildsen, Øivind (Journal article, 2015-08)
      Fingolimod (FTY720) is approved for treatment of relapsing–remitting multiple sclerosis. In vitro studies have found that fingolimod stimulates remyelination in cerebellar slices, but in vivo animal studies have not detected ...

    • Five salmon dinners per week were not sufficient to prevent the reduction in serum vitamin D in autumn at 60° north latitude: A randomised trial 

      Bratlie, Marianne; Hagen, Ingrid Valheim; Helland, Anita; Midttun, Øivind; Ulvik, Arve; Rosenlund, Grethe; Sveier, Harald; Mellgren, Gunnar; Ueland, Per Magne; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2020)
      Low serum concentrations of several vitamins have been linked to increased risk of diseases including insulin resistance and type 2 diabetes (T2D). Fish is a good source of several vitamins, and the prevalence of T2D is ...

    • Fixation, sex, and age: highest risk of revision for uncemented stems in elderly women - data from 66,995 primary total hip arthroplasties in the Norwegian Arthroplasty Register 

      Dale, Håvard; Børsheim, Sjur; Kristensen, Torbjørn; Fenstad, Anne Marie; Gjertsen, Jan-Erik; Hallan, Geir; Lie, Stein Atle; Furnes, Ove (Peer reviewed; Journal article, 2020)
      Background and purpose: There is no consensus on best method of fixation in hip arthroplasty. We investigated different modes of fixation in primary total hip arthroplasty (THA) and the influence of age and sex, to assess ...

    • Flåttbårne infeksjoner og selvrapporterte helseplager; en helseundersøkelse i Søgne kommune, Sør-Norge 

      Thortveit, Erik T. (Doctoral thesis, 2021-01-22)
      Background: Data on human exposure to tick-borne infections in Norway are scarce, and it is heavily debated whether tick-borne infections can cause chronic subjective health complaints. The main aims of this study were to ...

    • Fluctuations of sensorimotor processing in migraine: A controlled longitudinal study of beta event related desynchronization 

      Mykland, Martin Syvertsen; Bjørk, Marte-Helene; Stjern, Marit; Omland, Petter Moe; Uglem, Martin; Sand, Trond (Peer reviewed; Journal article, 2019-07-09)
      Background: The migraine brain seems to undergo cyclic fluctuations of sensory processing. For instance, during the preictal phase, migraineurs experience symptoms and signs of altered pain perception as well as other ...

    • Fluid-sensitive migration mechanisms predict association between metastasis and high interstitial fluid pressure in pancreatic cancer 

      Nævdal, Geir; Rofstad, Einar K; Søreide, Kjetil; Evje, Steinar (Journal article; Peer reviewed, 2022)
      A remarkable feature in pancreatic cancer is the propensity to metastasize early, even for small, early stage cancers. We use a computer-based pancreatic model to simulate tumor progression behavior where fluid-sensitive ...

    • An fMRI-study on single-sided deafness: Spectral-temporal properties and side of stimulation modulates hemispheric dominance 

      Heggdal, Peder Olaf Laugen; Aarstad, Hans Jørgen; Brännström, Jonas; Vassbotn, Flemming; Specht, Karsten (Peer reviewed; Journal article, 2019)
      Objective: Our main aim was to investigate the blood oxygenation level dependent (BOLD) response to monaural and binaural speech- and non-speech stimuli as measured with fMRI in subjects with single-sided deafness and in ...

    • Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis 

      Niemsiri, Vipavee; Rosenthal, Sara Brin; Nievergelt, Caroline M.; Maihofer, Adam X.; Marchetto, Maria C.; Santos, Renata; Shekhtman, Tatyana; Alliey-Rodriguez, Ney; Anand, Amit; Balaraman, Yokesh; Berrettini, Wade H.; Bertram, Holli; Burdick, Katherine E.; Calabrese, Joseph R.; Calkin, Cynthia V.; Conroy, Carla; Coryell, William H.; DeModena, Anna; Eyler, Lisa T.; Feeder, Scott; Fisher, Carrie; Frazier, Nicole; Frye, Mark A.; Gao, Keming; Garnham, Julie; Gershon, Elliot S.; Goes, Fernando S.; Goto, Toyomi; Harrington, Gloria J.; Jakobsen, Petter; Kamali, Masoud; Kelly, Marisa; Leckband, Susan G.; Lohoff, Falk W.; McCarthy, Michael J.; McInnis, Melvin G.; Craig, David; Millett, Caitlin E.; Mondimore, Francis; Morken, Gunnar; Nurnberger, John I.; Donovan, Claire O’; Ødegaard, Ketil Joachim; Ryan, Kelly; Schinagle, Martha; Shilling, Paul D.; Slaney, Claire; Stapp, Emma K.; Stautland, Andrea; Tarwater, Bruce; Zandi, Peter P.; Alda, Martin; Fisch, Kathleen M.; Gage, Fred H.; Kelsoe, John R. (Journal article; Peer reviewed, 2023)
      Lithium (Li) is one of the most effective drugs for treating bipolar disorder (BD), however, there is presently no way to predict response to guide treatment. The aim of this study is to identify functional genes and ...

    • Folic Acid and Risk of Preterm Birth, Preeclampsia, and Fetal Growth Restriction Among Women With Epilepsy A Prospective Cohort Study 

      Alvestad, Silje; Husebye, Elisabeth Synnøve Nilsen; Christensen, Jakob; Dreier, Julie Werenberg; Sun, Yuelian; Igland, Jannicke; Leinonen, Maarit; Gissler, Mika; Gilhus, Nils Erik; Tomson, Torbjörn; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)
      Background and Objectives Women with epilepsy treated with antiseizure medication (ASM) have increased risk of pregnancy complications including preterm birth, fetal growth restriction, and preeclampsia. We aimed to ...

    • Follow-up score, change score or percentage change score for determining clinical important outcome following surgery? An observational study from the Norwegian registry for Spine surgery evaluating patient reported outcome measures in lumbar spinal stenosis and lumbar degenerative spondylolisthesis 

      Austevoll, Ivar Magne; Gjestad, Rolf; Grotle, Margreth; Solberg, Tore; Brox, Jens Ivar; Hermansen, Erland; Rekeland, Frode; Indrekvam, Kari; Storheim, Kjersti; Hellum, Christian (Peer reviewed; Journal article, 2019-01-18)
      Background: Assessment of outcomes for spinal surgeries is challenging, and an ideal measurement that reflects all aspects of importance for the patients does not exist. Oswestry Disability Index (ODI), EuroQol (EQ-5D) and ...

    • Follow-up strategies for patients with splenic trauma managed non-operatively: the 2022 World Society of Emergency Surgery consensus document 

      Podda, Mauro; De Simone, Belinda; Ceresoli, Marco; Virdis, Francesco; Favi, Francesco; Larsen, Johannes Wiik; Coccolini, Federico; Sartelli, Massimo; Pararas, Nikolaos; Beka, Solomon Gurmu; Bonavina, Luigi; Bova, Raffaele; Pisanu, Adolfo; Abu-Zidan, Fikri; Balogh, Zsolt; Chiara, Osvaldo; Wani, Imtiaz; Stahel, Philip; Di Saverio, Salomone; Scalea, Thomas; Søreide, Kjetil; Sakakushev, Boris; Amico, Francesco; Martino, Costanza; Hecker, Andreas; de’Angelis, Nicola; Chirica, Mircea; Galante, Joseph; Kirkpatrick, Andrew; Pikoulis, Emmanouil; Kluger, Yoram; Bensard, Denis; Ansaloni, Luca; Fraga, Gustavo; Civil, Ian; Tebala, Giovanni Domenico; Di Carlo, Isidoro; Cui, Yunfeng; Coimbra, Raul; Agnoletti, Vanni; Sall, Ibrahima; Tan, Edward; Picetti, Edoardo; Litvin, Andrey; Damaskos, Dimitrios; Inaba, Kenji; Leung, Jeffrey; Maier, Ronald; Biffl, Walt; Leppaniemi, Ari; Moore, Ernest; Gurusamy, Kurinchi; Catena, Fausto (Journal article; Peer reviewed, 2022)
      Background In 2017, the World Society of Emergency Surgery published its guidelines for the management of adult and pediatric patients with splenic trauma. Several issues regarding the follow-up of patients with splenic ...