Blar i Department of Clinical Medicine på tittel

Viser treff 966-985 av 2043

    • Identity-by-descent mapping in a Scandinavian multiple sclerosis cohort 

      Westerlind, Helga; Imrell, Kerstin; Ramanujam, Ryan; Myhr, Kjell-Morten; Celius, Elisabeth Gulowsen; Harbo, Hanne Flinstad; Oturai, Annette Bang; Hamsten, Anders; Alfredsson, Lars; Olsson, Tomas; Kockum, Ingrid; Koski, Timo; Hillert, Jan (Peer reviewed; Journal article, 2015)
      In an attempt to map chromosomal regions carrying rare gene variants contributing to the risk of multiple sclerosis (MS), we identified segments shared identical-by-descent (IBD) using the software BEAGLE 4.0’s refined IBD ...

    • An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver 

      Fernández Moro, Carlos; Geyer, Natalie; Harrizi, Sara; Hamidi, Yousra; Söderqvist, Sara; Kuznyecov, Danyil; Tidholm Qvist, Evelina; Salmonson Schaad, Media; Hermann, Laura; Lindberg, Amanda; Heuchel, Rainer L.; Martín-Bernabé, Alfonso; Dhanjal, Soniya; Navis, Anna C.; Villard, Christina; del Valle, Andrea C.; Bozóky, Lorand; Sparrelid, Ernesto; Dirix, Luc; Strell, Carina; Östman, Arne; Schmierer, Bernhard; Vermeulen, Peter B.; Engstrand, Jennie; Bozóky, Béla; Gerling, Marco (Journal article; Peer reviewed, 2023)
      A perimetastatic capsule is a strong positive prognostic factor in liver metastases, but its origin remains unclear. Here, we systematically quantify the capsule’s extent and cellular composition in 263 patients with ...

    • IgA-nefropati 

      Haaskjold, Yngvar Lunde; Knoop, Thomas (Journal article; Peer reviewed, 2022)
      Immunglobulin A-nefropati (IgA-nefropati) er den vanligste formen for primær glomerulonefritt i verden og en hyppig årsak til alvorlig nyresvikt hos unge voksne. Diagnosen stilles ved nyrebiopsi. Til tross for at sykdommen ...

    • IGHV gene usage and mutational status in follicular lymphoma: Correlations with prognosis and patient age 

      Berget, Ellen; Molven, Anders; Løkeland, Turid; Helgeland, Lars; Vintermyr, Olav Karsten (Peer reviewed; Journal article, 2015-07)
      Follicular lymphoma (FL) is a heterogeneous disease with some patients developing progressively or transformed disease early, whereas others follow an indolent clinical course. We evaluated the prognostic value of ...

    • ILIVE Project Volunteer study. Developing international consensus for a European Core Curriculum for hospital end-of-life-care volunteer services, to train volunteers to support patients in the last weeks of life: A Delphi study 

      McGlinchey, Tamsin; Mason, Stephen R; Smeding, Ruthmarijke; Goosensen, Anne; Ruiz-Torreras, Inmaculada; Haugen, Dagny Renata Faksvåg; Bakan, Miša; Ellershaw, John E (Journal article; Peer reviewed, 2021)
      Background: Volunteers make a huge contribution to the health and wellbeing of the population and can improve satisfaction with care especially in the hospice setting. However, palliative and end-of-life-care volunteer ...

    • Illness perception in children with cerebral palsy, a longitudinal cohort study 

      Bjørgaas, Hanne Marit; Elgen, Irene Bircow; Hysing, Mari (Journal article; Peer reviewed, 2021)
      Background The perception of a disorder could be of importance both in problem solving behaviors, and in the emotional approach towards a disorder. Aims In this paper, we wanted to assess changes in illness perception ...

    • The Imaging and Cognition Genetics Conference 2011, ICG 2011: A Meeting of Minds 

      Le Hellard, Stephanie; Hanson, Isabel (Peer reviewed; Journal article, 2012-05-12)
      In June 2011, 70 researchers from the disciplines of cognitive science, genetics, psychology, psychiatry, neurobiology, and computer science gathered in Os, Norway, for the first Imaging and Cognition Genetics meeting. The ...

    • Imaging in Lyme neuroborreliosis 

      Lindland, Elisabeth Margrete Stokke; Solheim, Anne Marit; Andreassen, Silje; Paulsen, Else Quist; Eikeland, Randi; Ljøstad, Unn; Mygland, Åse; Elsais, Ahmed; Nygaard, Gro Owren; Lorentzen, Åslaug Rudjord; Harbo, Hanne Flinstad; Beyer, Mona K. (Peer reviewed; Journal article, 2018-10)
      Lyme neuroborreliosis (LNB) is a tick-borne spirochetal infection with a broad spectrum of imaging pathology. For individuals who live in or have travelled to areas where ticks reside, LNB should be considered among ...

    • Imaging of preclinical endometrial cancer models for monitoring tumor progression and response to targeted therapy 

      Espedal, Heidi; Fonnes, Tina; Fasmer, Kristine Eldevik; Krakstad, Camilla; Haldorsen, Ingfrid S. (Peer reviewed; Journal article, 2019-11-27)
      Endometrial cancer is the most common gynecologic malignancy in industrialized countries. Most patients are cured by surgery; however, about 15% of the patients develop recurrence with limited treatment options. Patient-derived ...

    • Imaging of the brain and of the lungs in young adults born prematurely and / or with a low birth weight. Radiological findings and associations with clinical features. 

      Aukland, Stein Magnus (Doctoral thesis, 2011-04-15)
      Background and Purpose: Premature birth is defined as a birth occurring earlier than 37 gestational weeks, and typically occurs in 6% of all pregnancies in Europe (1). All premature babies are at risk for health problems ...

    • Immediate and long-term impact of the COVID-19 pandemic on delivery of surgical services 

      Søreide, Kjetil; Hallet, Julie; Matthews, Jeffrey B.; Schnitzbauer, Andreas Anton; Line, Pål Dag; Lai, Paul B.S.; Otero, Javier; Callegaro, Dario; Warner, Shelley G.; Baxter, Nancy N.; Teh, Catherine S.C.; Ng-Kamstra, Joshua S.; Meara, John G.; Hagander, Lars E.; Lorenzon, Laura (Journal article; Peer reviewed, 2020)
      Background The ongoing pandemic is having a collateral health effect on delivery of surgical care to millions of patients. Very little is known about pandemic management and effects on other services, including delivery ...

    • Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies 

      Broce, Iris J.; Karch, Celeste M.; Wen, Natalie; Fan, Chun C.; Wang, Yunpeng; Hong Tan, Chin; Kouri, Naomi; Ross, Owen A.; Höglinger, Günter U.; Müller, Ulrich; Hardy, John; Momeni, Parastoo; Hess, Christopher P.; Dillon, William P.; Miller, Zachary A.; Bonham, Luke W.; Rabinovici, Gil D.; Rosen, Howard J.; Schellenberg, Gerard D.; Franke, Andre; Karlsen, Tom Hemming; Veldink, Jan H.; Ferrari, Raffaele; Yokoyama, Jennifer S.; Miller, Bruce L.; Andreassen, Ole Andreas; Dale, Anders; Desikan, Rahul S.; Sugrue, Leo P. (Peer reviewed; Journal article, 2018-01-09)
      Background: Converging evidence suggests that immune-mediated dysfunction plays an important role in the pathogenesis of frontotemporal dementia (FTD). Although genetic studies have shown that immune-associated loci are ...

    • The impact of age-related syndromes on ICU process and outcomes in very old patients 

      Vallet, Hélène; Guidet, Bertrand; Boumendil, Ariane; De Lange, Dylan W.; Leaver, Susannah; Szczeklik, Wojciech; Jung, Christian; Sviri, Sigal; Beil, Michael; Flaatten, Hans Kristian (Journal article; Peer reviewed, 2023)
      In this narrative review, we describe the most important age-related “syndromes” found in the old ICU patients. The syndromes are frailty, comorbidity, cognitive decline, malnutrition, sarcopenia, loss of functional autonomy, ...

    • Impact of body mass index and fat distribution on sex steroid levels in endometrial carcinoma: A retrospective study 

      van Weelden, Willem Jan; Fasmer, Kristine Eldevik; Tangen, Ingvild Løberg; IntHout, Joanna; Abbink, Karin; van Herwaarden, Antonius E.; Krakstad, Camilla; Massuger, Leon F.A.G.; Haldorsen, Ingfrid S.; Pijnenborg, Johanna M.A. (Peer reviewed; Journal article, 2019-06-07)
      Background Obesity is an important cause of multiple cancer types, amongst which endometrial cancer (EC). The relation between obesity and cancer is complicated and involves alterations in insulin metabolism, response to ...

    • Impact of childhood trauma on antipsychotic effectiveness in schizophrenia spectrum disorders: A prospective, pragmatic, semi-randomized trial 

      Mørkved, Nina; Johnsen, Erik; Kroken, Rune Andreas; Winje, Dagfinn; Larsen, Tor Ketil; Thimm, Jens; Rettenbacher, M.A.; Johannesen, C.A. Bartz; Løberg, Else-Marie (Journal article; Peer reviewed, 2022)
      Antipsychotic medications are generally effective in ameliorating psychotic symptoms in schizophrenia spectrum disorders (SSDs). Identifying predictors associated with poor treatment response is important for a personalized ...

    • Impact of Covid-19 Restrictions on Individual Placement and Support Service Delivery in Northern Norway 

      Wittlund, Sina Marion; Butenko, Daniil; Brandseth, Oda Lekve; Brinchmann, Beate; Killackey, Eóin; McDaid, David; Rinaldi, Miles; Mykletun, Arnstein (Journal article; Peer reviewed, 2022)
      Individual Placement and Support (IPS) is an evidence-based supported employment program that helps people with severe mental illness to achieve steady, meaningful employment in competitive mainstream jobs. The purpose of ...

    • Impact of different methods defining post-stroke neurocognitive disorder: The Nor-COAST study 

      Munthe-Kaas, Ragnhild; Aam, Stina; Ihle-Hansen, Hege; Lydersen, Stian; Knapskog, Anne Brita; Wyller, Torgeir Bruun; Fure, Brynjar; Thingstad, Pernille; Askim, Torunn; Beyer, Mona K.; Næss, Halvor; Seljeseth, Yngve Müller; Ellekjær, Hanne; Pendlebury, Sarah T.; Saltvedt, Ingvild (Journal article; Peer reviewed, 2020-03-16)
      Introduction Post‐stroke neurocognitive disorder (NCD) is common; prevalence varies between studies, partially related to lack of consensus on how to identify cases. The aim was to compare the prevalence of post‐stroke ...

    • Impact of EMG Changes in Continuous Vagal Nerve Monitoring in High-Risk Endocrine Neck Surgery 

      Brauckhoff, Katrin; Vik, Renate Kollevåg; Sandvik, Lorentz; Heimdal, John-Helge; Aas, Turid; Biermann, Martin; Brauckhoff, Michael (Peer reviewed; Journal article, 2016-03)
      Background: Continuous vagal intraoperative neuromonitoring (CIONM) of the recurrent laryngeal nerve (RLN) may reduce the risk of RLN lesions during high-risk endocrine neck surgery such as operation for large goiter ...

    • The impact of frailty on survival in elderly intensive care patients with COVID-19: the COVIP study 

      Jung, Christian; Flaatten, Hans; Fjølner, Jesper; Romano Bruno, Raphael; Wernly, Bernhard; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Joerg C.; Wolff, Georg; Kelm, Malte; Beil, Michael; Sviri, Sigal; van Heerden, Peter Vernon; Szczeklik, Wojciech; Czuczwar, Miroslaw; Elhadi, Muhammed; Joannidis, Michael; Oeyen, Sandra; Zafeiridis, Tilemachos; Marsh, Brian; Andersen, Finn Husøy; Moreno, Rui; Cecconi, Maurizio; Leaver, Susannah; Boumendil, Ariane; De Lange, Dylan W.; Guidet, Bertrand (Journal article; Peer reviewed, 2021)
      Background The COVID-19 pandemic has led highly developed healthcare systems to the brink of collapse due to the large numbers of patients being admitted into hospitals. One of the potential prognostic indicators in ...

    • The impact of gender, puberty, and pregnancy in patients with POLG disease 

      Hikmat, Omar; Naess, Karin; Engvall, Martin; Klingenberg, Claus; Rasmussen, Magnhild; Tallaksen, Chantal; Samsonsen, Christian; Brodtkorb, Eylert; Ostergaard, Elsebet; de Coo, Rene; Pias-Peleteiro, Leticia; Isohanni, Pirjo; Uusimaa, Johanna; Darin, Niklas; Rahman, Shamima; Bindoff, Laurence (Journal article; Peer reviewed, 2020)
      Objective To study the impact of gender, puberty, and pregnancy on the expression of POLG disease, one of the most common mitochondrial diseases known. Methods Clinical, laboratory, and genetic data were collected ...