Browsing Department of Clinical Medicine by Title
Now showing items 646-665 of 1079
-
Magnetic resonance imaging of craniovertebral structures: clinical significance in cervicogenic headaches
(Peer reviewed; Journal article, 2011-09-27)This paper aims to investigate the relevance of morphological changes in the main stabilizing structures of the craniocervical junction in persons with cervicogenic headache (CEH). A case control study of 46 consecutive ... -
Magnetic resonance imaging of the knee in Norway 2002–2004 (national survey): rapid increase, older patients, large geographic differences
(Peer reviewed; Journal article, 2007-07-22)Background: Magnetic resonance imaging (MRI) of the knee is the second most common MRI examination in Norway after head/brain MRI. Little has been published internationally on trends in the use of knee MRI after 1999. This ... -
Magnetization transfer ratio does not correlate to myelin content in the brain in the MOG-EAE mouse model
(Peer reviewed; Journal article, 2015-03-02)Magnetization transfer ratio (MTR) is a magnetic resonance imaging (MRI) method which may detect demyelination not detected by conventional MRI in the central nervous system of patients with multiple sclerosis (MS). A ... -
Mammographic density and histopathologic characteristics of screen-detected tumors in the Norwegian Breast Cancer Screening Program
(Peer reviewed; Journal article, 2015-09-18)Background. High mammographic density might mask breast tumors, resulting in delayed diagnosis or missed cancers. Purpose. To investigate the association between mammographic density and histopathologic tumor characteristics ... -
A mass cytometry receptor occupancy study of natalizumab therapy in multiple sclerosis
(Doctoral thesis, 2020-06-05)Background: Natalizumab is a therapeutic antibody that effectively reduces disease activity in relapsing remitting multiple sclerosis (RRMS) by binding α4 integrin on leukocytes and preventing leukocyte migration into the ... -
Mass spectral profiling and multivariate analysis for detection of biomarker signatures. Application to multiple sclerosis
(Doctoral thesis, 2010-10-28)Mass spectrometry based protein profiling and biomarker discovery has given rise to the field of clinical proteomics. The underlying assumption is that proteins can provide information of diagnostic or therapeutic value ... -
Maternal and Newborn Vitamin D-Binding Protein, Vitamin D Levels, Vitamin D Receptor Genotype, and Childhood Type 1 Diabetes
(Peer reviewed; Journal article, 2019-04)OBJECTIVE Circumstantial evidence links 25-hydroxy vitamin D [25(OH)D], vitamin D–binding protein (DBP), vitamin D–associated genes, and type 1 diabetes (T1D), but no studies have jointly analyzed these. We aimed to ... -
The Maternal and Paternal Effects on Clinically and Surgically Defined Osteoarthritis
(Peer reviewed; Journal article, 2019-11)Objective: It is currently unknown whether osteoarthritis (OA) is inherited mainly from the mother, father, or both. This study was undertaken to explore the effect of maternal and paternal factors on hip, knee, and hand ... -
Maternal complications in pregnancy and childbirth for women with epilepsy: time trends in a nationwide cohort
(Peer reviewed; Journal article, 2019)Objective: Obstetric trends show changes in complication rates and maternal characteristics such as caesarean section, induced labour, and maternal age. To what degree such general time trends and changing patterns of ... -
Maternal Seafood Consumption and Serum Levels of p.p'-DDE and PCB-153 in Mother and Child
(Master thesis, 2014-05-15)Background: While seafood is a natural part of a healthy and balanced diet, it may also contain some undesirable environmental contaminants such as persistent organic pollutants (POPs), which can have detrimental effects ... -
Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses
(Peer reviewed; Journal article, 2011-01-05)Background: Design of tumour specific immunotherapies using the patients’ own dendritic cells (DC) is a fast advancing scientific field. The functional qualities of the DC generated in vitro are critical, and today’s gold ... -
Måleegenskaper ved den norske versjonen av Children’s Global Assessment Scale (CGAS)
(Peer reviewed; Journal article, 2018-10-23)Beskrivelse. Children’s Global Assessment Scale (CGAS) ble laget av David Shaffer og medarbeidere i 1983. Den skåres av kliniker og er et mål på barns psykososiale funksjonsnivå i den siste måneden før vurderingstidspunktet ... -
The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian—but not endometrial cancer
(Peer reviewed; Journal article, 2016-02-11)The MDM4 protein (also known as MDMX or HDMX) is a negative regulator of p53, not only by direct interaction but also through its interaction with MDM2. Further, MDM4 overexpression and amplification have been observed in ... -
Measurement of renal functional response using iohexol clearance—a study of different outpatient procedures
(Peer reviewed; Journal article, 2019)Background: Glomerular filtration rate (GFR) increases after a heavy protein load; an increase termed renal functional response (RFR). Decreased RFR could be a marker of early kidney damage, but published methods are ... -
Measuring pressure pain threshold in the cervical region of dizzy patients-The reliability of a pressure algometer
(Peer reviewed; Journal article, 2018)Objectives: A tool for measuring neck pain in patients with dizziness is needed to further investigate the relationship between the two symptoms. The objective of this study was to examine the reliability and validity of ... -
The mediating effect of body mass index on the relationship between smoking and hip or knee replacement due to primary osteoarthritis. A population-based cohort study (the HUNT study)
(Peer reviewed; Journal article, 2017-12-28)To investigate the total effect of smoking on total hip or knee replacement (THR/TKR) due to primary osteoarthritis (OA) and to quantify the indirect effect of smoking through body mass index (BMI). Participants from the ... -
Medical abortion with mifepristone and home administration of misoprostol up to 63 days' gestation
(Peer reviewed; Journal article, 2014-05-23)Objective. To evaluate the acceptability and efficacy of medical abortion at home up to 63 days’ gestation without limits on travel distance to a registered institution. Design. Observational prospective study. Setting. ... -
Medication Use and Prognosis of Alzheimer's Disease and Lewy Body Dementia : Hospitalization and Mortality
(Doctoral thesis, 2020-10-30)Background: There is no curative treatment available for the cause of dementia, and few drugs are approved for symptomatic treatment. In addition, knowledge about prognosis related to hospitalization and mortality is scarce ... -
Mental Health and care situation in school-aged children prenatally exposed to alcohol and other substances: a hospital based study
(Doctoral thesis, 2018-10-31)Background: Prenatal exposure to substances, including alcohol, opiates and illicit drugs, may influence a child’s neurodevelopment and possibly impact on their subsequent mental health. Maternal use of substances is an ...