Browsing Department of Clinical Medicine by Title
Now showing items 842-861 of 1397
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Magnetic resonance imaging of craniovertebral structures: clinical significance in cervicogenic headaches
(Peer reviewed; Journal article, 2011-09-27)This paper aims to investigate the relevance of morphological changes in the main stabilizing structures of the craniocervical junction in persons with cervicogenic headache (CEH). A case control study of 46 consecutive ... -
Magnetic resonance imaging of the knee in Norway 2002–2004 (national survey): rapid increase, older patients, large geographic differences
(Peer reviewed; Journal article, 2007-07-22)Background: Magnetic resonance imaging (MRI) of the knee is the second most common MRI examination in Norway after head/brain MRI. Little has been published internationally on trends in the use of knee MRI after 1999. This ... -
Magnetic Resonance Spectroscopy in Depressed Subjects Treated With Electroconvulsive Therapy—A Systematic Review of Literature
(Journal article; Peer reviewed, 2021)Electroconvulsive therapy (ECT) is considered to be the most effective acute treatment for otherwise treatment resistant major depressive episodes, and has been used for over 80 years. Still, the underlying mechanism of ... -
Magnetization transfer ratio does not correlate to myelin content in the brain in the MOG-EAE mouse model
(Peer reviewed; Journal article, 2015-03-02)Magnetization transfer ratio (MTR) is a magnetic resonance imaging (MRI) method which may detect demyelination not detected by conventional MRI in the central nervous system of patients with multiple sclerosis (MS). A ... -
Male to female ratios in autism spectrum disorders by age, intellectual disability and attention-deficit/hyperactivity disorder
(Journal article; Peer reviewed, 2021)Objective To examine the gender distribution in ASD in adults compared with children and the impact of comorbid intellectual disability (ID) and attention-deficit/hyperactivity disorder (ADHD) on the male to female ratio ... -
Mammographic density and histopathologic characteristics of screen-detected tumors in the Norwegian Breast Cancer Screening Program
(Peer reviewed; Journal article, 2015-09-18)Background. High mammographic density might mask breast tumors, resulting in delayed diagnosis or missed cancers. Purpose. To investigate the association between mammographic density and histopathologic tumor characteristics ... -
Management and outcomes in critically ill nonagenarian versus octogenarian patients
(Journal article; Peer reviewed, 2021)Background: Intensive care unit (ICU) patients age 90 years or older represent a growing subgroup and place a huge financial burden on health care resources despite the benefit being unclear. This leads to ethical problems. ... -
Management of cluster headache and other trigeminal autonomic cephalalgias in pregnancy and breastfeeding
(Journal article; Peer reviewed, 2021)Many clinicians lack experience in managing trigeminal autonomic cephalalgias (TACs) in pregnancy and lactation. In addition to cluster headache, TACs include hemicrania continua, paroxysmal hemicrania, and short-lasting ... -
MAP kinase phosphatase MKP-1 regulates p-ERK1/2 signaling pathway with fluoride treatment
(Journal article; Peer reviewed, 2021)Dental fluorosis is characterized by hypomineralization of tooth enamel caused by ingestion of excessive fluoride during enamel formation. Excess fluoride could have effects on the ERK signaling, which is essential for the ... -
A mass cytometry receptor occupancy study of natalizumab therapy in multiple sclerosis
(Doctoral thesis, 2020-06-05)Background: Natalizumab is a therapeutic antibody that effectively reduces disease activity in relapsing remitting multiple sclerosis (RRMS) by binding α4 integrin on leukocytes and preventing leukocyte migration into the ... -
Mass spectral profiling and multivariate analysis for detection of biomarker signatures. Application to multiple sclerosis
(Doctoral thesis, 2010-10-28)Mass spectrometry based protein profiling and biomarker discovery has given rise to the field of clinical proteomics. The underlying assumption is that proteins can provide information of diagnostic or therapeutic value ... -
Maternal and Newborn Vitamin D-Binding Protein, Vitamin D Levels, Vitamin D Receptor Genotype, and Childhood Type 1 Diabetes
(Peer reviewed; Journal article, 2019-04)OBJECTIVE Circumstantial evidence links 25-hydroxy vitamin D [25(OH)D], vitamin D–binding protein (DBP), vitamin D–associated genes, and type 1 diabetes (T1D), but no studies have jointly analyzed these. We aimed to ... -
The Maternal and Paternal Effects on Clinically and Surgically Defined Osteoarthritis
(Peer reviewed; Journal article, 2019-11)Objective: It is currently unknown whether osteoarthritis (OA) is inherited mainly from the mother, father, or both. This study was undertaken to explore the effect of maternal and paternal factors on hip, knee, and hand ... -
Maternal complications in pregnancy and childbirth for women with epilepsy: time trends in a nationwide cohort
(Peer reviewed; Journal article, 2019)Objective: Obstetric trends show changes in complication rates and maternal characteristics such as caesarean section, induced labour, and maternal age. To what degree such general time trends and changing patterns of ... -
Maternal Seafood Consumption and Serum Levels of p.p'-DDE and PCB-153 in Mother and Child
(Master thesis, 2014-05-15)Background: While seafood is a natural part of a healthy and balanced diet, it may also contain some undesirable environmental contaminants such as persistent organic pollutants (POPs), which can have detrimental effects ... -
Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses
(Peer reviewed; Journal article, 2011-01-05)Background: Design of tumour specific immunotherapies using the patients’ own dendritic cells (DC) is a fast advancing scientific field. The functional qualities of the DC generated in vitro are critical, and today’s gold ... -
Måleegenskaper ved den norske versjonen av Children’s Global Assessment Scale (CGAS)
(Peer reviewed; Journal article, 2018-10-23)Beskrivelse. Children’s Global Assessment Scale (CGAS) ble laget av David Shaffer og medarbeidere i 1983. Den skåres av kliniker og er et mål på barns psykososiale funksjonsnivå i den siste måneden før vurderingstidspunktet ... -
The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian—but not endometrial cancer
(Peer reviewed; Journal article, 2016-02-11)The MDM4 protein (also known as MDMX or HDMX) is a negative regulator of p53, not only by direct interaction but also through its interaction with MDM2. Further, MDM4 overexpression and amplification have been observed in ... -
Measurement of renal functional response using iohexol clearance—a study of different outpatient procedures
(Peer reviewed; Journal article, 2019)Background: Glomerular filtration rate (GFR) increases after a heavy protein load; an increase termed renal functional response (RFR). Decreased RFR could be a marker of early kidney damage, but published methods are ...