Blar i Department of Clinical Medicine på tidsskrift "BMC Nephrology"
Viser treff 1-7 av 7
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Characterization of glomerular extracellular matrix in IgA nephropathy by proteomic analysis of laser-captured microdissected glomeruli
(Peer reviewed; Journal article, 2019-11-14)Background IgA nephropathy (IgAN) involves mesangial matrix expansion, but the proteomic composition of this matrix is unknown. The present study aimed to characterize changes in extracellular matrix in IgAN. Methods In ... -
Developing nephrology services in low income countries: A case of Tanzania
(Peer reviewed; Journal article, 2019-10-17)Background: The burden of kidney diseases is reported to be higher in lower- and middle-income countries as compared to developed countries, and countries in sub-Saharan Africa are reported to be most affected. Health ... -
Fine needle aspirates of kidneys: A promising tool for RNA sequencing in native and transplanted kidneys
(Peer reviewed; Journal article, 2018-09-18)Background: Transcriptome analysis is emerging as emerging as a promising tool to enhance precision of diagnosis and monitoring in solid organ transplantation. Clinical progress has however been hampered by the current ... -
Glomerular proteomic profiling reveals early differences between preexisting and de novo type 2 diabetes in human renal allografts
(Journal article; Peer reviewed, 2023)Background Diabetes mellitus (DM), either preexisting or developing after transplantation, remains a crucial clinical problem in kidney transplantation. To obtain insights into the molecular mechanisms underlying PTDM ... -
High rates of central obesity and sarcopenia in CKD irrespective of renal replacement therapy - An observational cross-sectional study
(Journal article; Peer reviewed, 2018-10-11)Background: Poor nutritional status of patients with renal disease has been associated with worsening of renal function and poor health outcomes. Simply measuring weight and height for calculation of the body mass index ... -
Proteomic signature of tubulointerstitial tissue predicts prognosis in IgAN
(Journal article; Peer reviewed, 2022-03-24)Background: IgA nephropathy (IgAN) is associated with a significant risk of progression to kidney failure. Tubular atrophy is an established important risk factor for progressive disease, but few studies have investigated ... -
Utilizing the MEST score for prognostic staging in IgA nephropathy
(Journal article; Peer reviewed, 2022)Background The Oxford classification/MEST score is an established histopathologic scoring system for patients with IgA nephropathy (IgAN). The objective of this study was to derive a prognostic model for IgAN based on the ...