Browsing Department of Clinical Medicine by Journals "BMJ Open"
Now showing items 1-20 of 24
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Acute kidney injury in patients with COVID-19 in the intensive care unit: Evaluation of risk factors and mortality in a national cohort
(Journal article; Peer reviewed, 2022)Objectives: Acute kidney injury (AKI) is a frequent complication among critical ill patients with COVID-19, but the actual incidence is unknown as AKI-incidence varies from 25% to 89% in intensive care unit (ICU) populations. ... -
Antibiotic-loaded bone cement in prevention of periprosthetic joint infections in primary total knee arthroplasty: A register-based multicentre randomised controlled non-inferiority trial (ALBA trial)
(Journal article; Peer reviewed, 2021)Introduction The current evidence on the efficacy of antibiotic-loaded bone cement (ALBC) in reducing the risk of periprosthetic joint infections (PJI) after primary joint reconstruction is insufficient. In several European ... -
Assessing a nurse-assisted eHealth intervention posthospital discharge in adult patients with non-communicable diseases: a protocol for a feasibility study
(Journal article; Peer reviewed, 2023)Introduction A growing number of patients with non-communicable diseases (NCDs), such as heart failure (HF) and colorectal cancer (CRC), are prone to comorbidity, a high rate of readmissions and complex healthcare needs. ... -
Assessing the association of oxytocin augmentation with obstetric anal sphincter injury in nulliparous women: A population-based, case-control study
(Peer reviewed; Journal article, 2014-07-24)Objective To assess the association of oxytocin augmentation with obstetric anal sphincter injury among nulliparous women. Design Population-based, case–control study. Setting Primary and secondary teaching hospital serving ... -
Causal modelling of variation in clinical practice and long-term outcomes of ADHD using Norwegian registry data: The ADHD controversy project
(Journal article; Peer reviewed, 2021)Introduction Attention-deficit/hyperactivity disorder (ADHD) is among the most common mental disorders in children and adolescents, and it is a strong risk factor for several adverse psychosocial outcomes over the lifespan. ... -
Comparing the impact of upfront radiosurgery versus expectation in vestibular schwannoma (the V-REX study): protocol for a randomised, observer-blinded, 4-year, parallel-group, single-centre, superiority study
(Journal article; Peer reviewed, 2021)Introduction The optimal management of small-sized to medium-sized vestibular schwannoma (VS) is a matter of controversy. Clinical results of the prevailing treatment modalities (microsurgery, stereotactic radiosurgery ... -
Compliance with national guidelines for antibiotic prophylaxis in hip fracture patients: A quality assessment study of 13 329 patients in the Norwegian Hip Fracture Register
(Journal article; Peer reviewed, 2020)Objective We assessed compliance with new guidelines for prophylactic antibiotics in hip fracture surgery in Norway introduced in 2013. Design The data from the Norwegian Hip Fracture Register was used to assess the ... -
Cost–utility analysis of antibiotic treatment in patients with chronic low back pain and Modic changes: results from a randomised, placebo-controlled trial in Norway (the AIM study)
(Journal article; Peer reviewed, 2020)Objective To evaluate the cost–utility of 100 days of antibiotics in patients with chronic low back pain (LBP) and type I or II Modic changes included in the Antibiotic treatment In patients with chronic low back pain ... -
Determining universal processes related to best outcome in emergency abdominal surgery: A multicentre, international, prospective cohort study
(Peer reviewed; Journal article, 2014-10-29)Introduction: Emergency abdominal surgery outcomes represent an internationally important marker of healthcare quality and capacity. In this study, a novel approach to investigating global surgical outcomes is proposed, ... -
Early indicators of disease progression in Fabry disease that may indicate the need for disease-specific treatment initiation: Findings from the opinion-based PREDICT-FD modified Delphi consensus initiative
(Journal article; Peer reviewed, 2020)Objectives The PRoposing Early Disease Indicators for Clinical Tracking in Fabry Disease (PREDICT-FD) initiative aimed to reach consensus among a panel of global experts on early indicators of disease progression that may ... -
Frequent refresher training on newborn resuscitation and potential impact on perinatal outcome over time in a rural Tanzanian hospital: An observational study
(Peer reviewed; Journal article, 2019)Objectives: Globally, perinatal mortality remains high, especially in sub-Saharan countries, mainly because of inadequate obstetric and newborn care. Helping Babies Breathe (HBB) resuscitation training as part of a continuous ... -
From hearing to seeing: medical dispatchers' experience with use of video streaming in medical emergency calls - a qualitative study
(Journal article; Peer reviewed, 2022)Objectives: Video streaming has recently been introduced as an additional tool for communication between medical dispatchers and caller. Research implies that video streaming may be a useful tool for the dispatchers, but ... -
Is long-bout sedentary behaviour associated with long-term glucose levels 3 months after acute ischaemic stroke? A prospective observational cohort study
(Journal article; Peer reviewed, 2020)Background and purpose Sedentary behaviour is a risk factor for vascular disease and stroke patients are more sedentary than their age-matched peers. The association with glucose levels, as a potential mediator, is ... -
Live well, die well - an international cohort study on experiences, concerns and preferences of patients in the last phase of life: the research protocol of the iLIVE study
(Journal article; Peer reviewed, 2022)Introduction Adequately addressing the needs of patients at the end of life and their relatives is pivotal in preventing unnecessary suffering and optimising their quality of life. The purpose of the iLIVE study is to ... -
Longitudinal follow-up of employment status in patients with chronic fatigue syndrome after mononucleosis
(Peer reviewed; Journal article, 2015-11-26)Objective: To examine the effect of early clinical and demographic factors on occupational outcome, return to work or awarded permanent disability pension in young patients with chronic fatigue syndrome (CFS). Design: ... -
Patients' experiences of living with patellar instability before and after surgery: A qualitative interview study
(Journal article; Peer reviewed, 2023)Objectives To explore the experience of living with patellar instability before and after surgery. Design Qualitative individual semistructured interviews of patients with patellar instability using a four-step thematic ... -
Predictors of chronic pain and level of physical function in total knee arthroplasty: a protocol for a systematic review and meta-analysis
(Journal article; Peer reviewed, 2020)Introduction: One in five patients undergoing total knee arthroplasty (TKA) experience unchanged or worse pain and physical function 1 year after surgery. Identifying risk factors for unfavourable outcomes is necessary to ... -
Prevalence and impact of exercise-induced laryngeal obstruction in asthma: a study protocol for a cross-sectional and longitudinal study
(Journal article; Peer reviewed, 2023)Introduction Exercise-induced laryngeal obstruction (EILO) and exercise-induced asthma can cause troublesome respiratory symptoms that can be difficult to distinguish between. Further, there is now a growing appreciation ... -
A prospective observational study of why people are medically evacuated from offshore installations in the North Sea
(Journal article; Peer reviewed, 2020)Objectives Few studies have described evacuations due to medical emergencies from the offshore installations in the North Sea, though efficient medical service is essential for the industrial activities in this area. The ... -
Protocol for data extraction: how realworld data have been used in the National Institute for Health and Care Excellence appraisals of cancer therapy
(Journal article; Peer reviewed, 2022)Introduction Due to the limitations of relying on randomised controlled trials, the potential benefits of real-world data (RWD) in enriching evidence for health technology assessment (HTA) are highlighted. Despite increased ...