Browsing Department of Clinical Medicine by Journals "Frontiers in Neurology"

Now showing items 1-15 of 15

    • Association of SNCA Parkinson's Disease Risk Polymorphisms With Disease Progression in Newly Diagnosed Patients 

      Szwedo, Aleksandra A; Pedersen, Camilla C; Ushakova, Anastasia; Forsgren, Lars; Tysnes, Ole-Bjørn; Counsell, Carl E.; Alves, Guido Werner; Lange, Johannes; Macleod, Angus D.; Maple-Grødem, Jodi (Journal article; Peer reviewed, 2021)
      Objectives: To evaluate the impact of SNCA polymorphisms originally identified as risk factors for Parkinson's disease (PD) on the clinical presentation and progression of the disease in a large cohort of population-based ...

    • Case report: Pain in anti-DPPX encephalitis 

      Bjerknes, Tale Litlere; Steihaug, Ole Martin; Haugen, Mette; Hjelland, Ina Elen; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2022)
      Encephalitis due to antibodies targeting dipeptidyl-peptidase-like protein 6 (DPPX), a potassium channel subunit, is rare. The illness is typically characterized by a triad of weight loss, CNS hyperexcitability and cognitive ...

    • Case report: Seropositive myasthenia gravis complicated by limbic encephalitis positive for antibodies to AMPAR and Lgi1 

      Nes, Magne Solberg; Haugen, Mette; Haugland, Hans Kristian; Gilhus, Nils Erik; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2023-10-12)
      Objectives: Autoantibodies to the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) and leucine-rich glioma-inactivated 1 (Lgi1) are associated with autoimmune encephalitis. We described an acetylcholine ...

    • The Course of Carotid Plaque Vulnerability Assessed by Advanced Neurosonology 

      Aarli, Sander Johan; Thomassen, Lars; Waje-Andreassen, Ulrike; Logallo, Nicola; Kvistad, Christopher Elnan; Næss, Halvor; Fromm, Annette (Journal article; Peer reviewed, 2021-08-20)
      Background: Carotid artery atherosclerosis is a major risk factor for ischemic stroke. This risk is related to plaque vulnerability and is characterized by plaque morphology, intraplaque neovascularization, and cerebral ...

    • CRMP5 Antibodies—Diagnostic Challenges 

      Totland, Cecilie; Haugen, Mette; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2021-09-22)
      CRMP5-associated paraneoplastic neurological syndromes (PNS) are rare, and only few studies describe larger cohorts of patients with CRMP5 antibodies. We have included 24 patients with CRMP5 antibodies and compared clinical ...

    • Diagnosis and therapy of myasthenia gravis—the patients’ perspective: a cross-sectional study 

      Sobierajski, Tomasz; Lasek-Bal, Anetta; Krzystanek, Marek; Gilhus, Nils Erik (Journal article; Peer reviewed, 2023)
      The survey aimed to explore patients’ perspectives with myasthenia gravis (MG) toward the diagnosis made and the therapy used to treat MG. The survey was conducted with a quantitative method, using the CAWI technique. A ...

    • Myasthenia gravis can have consequences for pregnancy and the developing child 

      Gilhus, Nils Erik (Journal article; Peer reviewed, 2020)
      Myasthenia gravis (MG) with onset below 50 years, thymic hyperplasia and acetylcholine receptor (AChR) antibodies is more common in females than in males. For a relatively large group of MG patients, pregnancy represents ...

    • Natural Variation of Vitamin D and Neurofilament Light Chain in Relapsing-Remitting Multiple Sclerosis 

      Røsjø, Egil Rørvik; Lindstrøm, Jonas Christoffer; Holmøy, Trygve; Myhr, Kjell-Morten; Varhaug, Kristin Nielsen; Torkildsen, Øivind Fredvik (Journal article; Peer reviewed, 2020-04-30)
      Background: High serum levels of 25-hydroxyvitamin D (25(OH)D) have been found among patients with a favorable disease course in relapsing-remitting MS (RRMS), indicating that this may limit clinical deterioration. Clinical ...

    • Neurofilament light chain as a biomarker in multiple sclerosis 

      Varhaug, Kristin Nielsen; Torkildsen, Øivind; Myhr, Kjell-Morten; Vedeler, Christian A. (Peer reviewed; Journal article, 2019-04-05)
      Due to the unpredictable course and heterogenous treatment response in multiple sclerosis (MS), there is a clear need for biomarkers that reflect disease activity in the clinical follow-up of these patients. Neurofilaments ...

    • Occurrence and severity of myasthenic crisis in an unselected Turkish cohort of patients with myasthenia gravis 

      Ozyurt Kose, Selen; Nazli, Ezgi; Tutkavul, Kemal; Gilhus, Nils Erik (Journal article; Peer reviewed, 2023)
      Myasthenia gravis (MG) is a disorder of the neuromuscular junction that can deteriorate into myasthenic crisis, involving weakness of bulbar and respiratory muscles. In this study, we describe the clinical manifestations ...

    • Paraneoplastic and Other Autoimmune Encephalitides: Antineuronal Antibodies, T Lymphocytes, and Questions of Pathogenesis 

      Greenlee, John E.; Carlson, Noel G.; Abbatemarco, Justin R.; Herdlevær, Ida Ajvazi; Clardy, Stacey L.; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2022)
      Autoimmune and paraneoplastic encephalitides represent an increasingly recognized cause of devastating human illness as well as an emerging area of neurological injury associated with immune checkpoint inhibitors. Two ...

    • REM sleep behavior disorder is not associated with a more rapid cognitive decline in mild dementia 

      Chwiszczuk, Luiza; Breitve, Monica Haraldseid; Brønnick, Kolbjørn Selvåg; Gjerstad, Michaela D; Hynninen, Kia Minna; Aarsland, Dag; Rongve, Arvid (Peer reviewed; Journal article, 2017-08-07)
      Objectives: REM sleep behavior disorder (RBD) is associated with cognitive dysfunctions and is a risk factor for development of mild cognitive impairment and dementia. However, it is unknown whether RBD is associated with ...

    • The Romberg sign, unilateral vestibulopathy, cerebrovascular risk factors, and long-term mortality in dizzy patients 

      Berge, Jan Erik; Goplen, Frederik Kragerud; Aarstad, Hans Jørgen; Storhaug, Tobias Andre; Nordahl, Stein Helge Glad (Journal article; Peer reviewed, 2022)
      Objectives: Describe the relationship between unsteadiness, canal paresis, cerebrovascular risk factors, and long-term mortality in patients examined for dizziness of suspected vestibular origin. Study design: Observational ...

    • Spike count and morphology in the classification of epileptiform discharges 

      Aanestad, Eivind; Gilhus, Nils Erik; Olberg, Henning Kristian; Kural, Mustafa Aykut; Beniczky, Sándor; Brøgger, Jan (Journal article; Peer reviewed, 2023)
      Purpose: The purpose of this study is to investigate the impact of Bergen Epileptiform Morphology Score (BEMS) and interictal epileptiform discharge (IED) candidate count in EEG classification. Methods: We included 400 ...

    • User Involvement in Myasthenia Gravis Research 

      Gilhus, Nils Erik; Hovland, Sandra Iren Barkås (Journal article; Peer reviewed, 2022-06-02)