A community-based geological reconstruction of Antarctic Ice Sheet deglaciation since the Last Glacial Maximum
Bentley, Michael J.; Ocofaigh, Colm Ó.; Anderson, John B.; Conway, Howard; Davies, Bethan; Graham, Alastair G.C.; Hillenbrand, Claus-Dieter; Hodgson, Dominic A.; Jamieson, Stewart S.R.; Larter, Robert D.; Mackintosh, Andrew; Smith, James A.; Verleyen, Elie; Ackert, Robert P.; Bart, Philip J.; Berg, Sonja; Brunstein, Daniel; Canals, Miquel; Colhoun, Eric A.; Crosta, Xavier; Dickens, William A.; Domack, Eugene; Dowdeswell, Julian A.; Dunbar, Robert; Ehrmann, Werner; Evans, Jeffrey; Favier, Vincent; Fink, David; Fogwill, Christopher J.; Glasser, Neil F.; Gohl, Karsten; Golledge, Nicholas R.; Goodwin, Ian; Gore, Damian B.; Greenwood, Sarah L.; Hall, Brenda L.; Hall, Kevin; Hedding, David W.; Hein, Andrew S.; Hocking, Emma P.; Jakobsson, Martin; Johnson, Joanne S.; Jomelli, Vincent; Jones, R. Selwyn; Klages, Johann P.; Kristoffersen, Yngve; Kuhn, Gerhard; Leventer, Amy; Licht, Kathy; Lilly, Katherine; Lindow, Julia; Livingstone, Stephen J.; Massé, Guillaume; McGlone, Matt S.; Mckay, Robert M.; Melles, Martin; Miura, Hideki; Mulvaney, Robert; Nel, Werner; Nitsche, Frank O.; O'Brien, Philip E.; Post, Alexandra L.; Roberts, Stephen J.; Saunders, Krystyna M.; Selkirk, Patricia M.; Simms, Alexander R.; Spiegel, Cornelia; Stolldorf, Travis D.; Sugden, David E.; van der Putten, Nathalie; van Ommen, Tas; Verfaillie, Deborah; Vyverman, Wim; Wagner, Bernd; White, Duanne A.; Witus, Alexandra E.; Zwartz, Dan
Peer reviewed, Journal article
Published version
Date
2014-09-15Metadata
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- Department of Earth Science [1121]
Original version
https://doi.org/10.1016/j.quascirev.2014.06.025Abstract
A robust understanding of Antarctic Ice Sheet deglacial history since the Last Glacial Maximum is important in order to constrain ice sheet and glacial-isostatic adjustment models, and to explore the forcing mechanisms responsible for ice sheet retreat. Such understanding can be derived from a broad range of geological and glaciological datasets and recent decades have seen an upsurge in such data gathering around the continent and Sub-Antarctic islands. Here, we report a new synthesis of those datasets, based on an accompanying series of reviews of the geological data, organised by sector. We present a series of timeslice maps for 20 ka, 15 ka, 10 ka and 5 ka, including grounding line position and ice sheet thickness changes, along with a clear assessment of levels of confidence. The reconstruction shows that the Antarctic Ice sheet did not everywhere reach the continental shelf edge at its maximum, that initial retreat was asynchronous, and that the spatial pattern of deglaciation was highly variable, particularly on the inner shelf. The deglacial reconstruction is consistent with a moderate overall excess ice volume and with a relatively small Antarctic contribution to meltwater pulse 1a. We discuss key areas of uncertainty both around the continent and by time interval, and we highlight potential priorities for future work. The synthesis is intended to be a resource for the modelling and glacial geological community.
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ElsevierJournal
Quaternary Science ReviewsCopyright
Copyright 2014 The AuthorsRelated items
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Jaime; Mirjalili, Mohammad Reza; Mirkopoulou, Daphne; Mirrakhimov, Erkin; Mišigoj-Duraković, Marjeta; Mistretta, Antonio; Mocanu, Veronica; Modesti, Pietro A.; Moghaddam, Sahar Saeedi; Mohajer, Bahram; Mohamed, Mostafa K.; Mohamed, Shukri F.; Mohammad, Kazem; Mohammadi, Mohammad Reza; Mohammadi, Zahra; Mohammadifard, Noushin; Mohammadpourhodki, Reza; Mohan, Viswanathan; Mohanna, Salim; Yusoff, Muhammad Fadhli Mohd; Mohebbi, Iraj; Mohebi, Farnam; Moitry, Marie; Møllehave, Line T.; Møller, Niels C.; Molnár, Dénes; Momenan, Amirabbas; Mondo, Charles K.; Montenegro Mendoza, Roger A.; Monterrubio-Flores, Eric; Monyeki, Kotsedi Daniel K.; Moon, Jin Soo; Moosazadeh, Mahmood; Mopa, Hermine T.; Moradpour, Farhad; Moreira, Leila B.; Morejon, Alain; Moreno, Luis A.; Morey, Francis; Morgan, Karen; Morin, Suzanne N.; Mortensen, Erik Lykke; Moschonis, George; Moslem, Alireza; Mossakowska, Malgorzata; Mostafa, Aya; Mostafavi, Seyed-Ali; Mota-Pinto, Anabela; Mota, Jorge; Motlagh, Mohammad Esmaeel; Motta, Jorge; Moura-dos-Santos, Marcos André; Movsesyan, Yeva; Msyamboza, Kelias P.; Mu, Thet Thet; Muc, Magdalena; Muca, Florian; Mugoša, Boban; Muiesan, Maria L.; Müller-Nurasyid, Martina; Münzel, Thomas; Mursu, Jaakko; Murtagh, Elaine M.; Musa, Kamarul Imran; Milanović, Sanja Musić; Musil, Vera; Musinguzi, Geofrey; Muyer, Muel Telo M. C.; Nabipour, Iraj; Naderimagham, Shohreh; Nagel, Gabriele; Najafi, Farid; Nakamura, Harunobu; Nalecz, Hanna; Námešná, Jana; Nang, Ei Ei K.; Nangia, Vinay B.; Nankap, Martin; Narake, Sameer; Nardone, Paola; Naseri, Take; Nauck, Matthias; Neal, William A.; Nejatizadeh, Azim; Nekkantti, Chandini; Nelis, Keiu; Nenko, Ilona; Neovius, Martin; Nervi, Flavio; Ng, Tze Pin; Nguyen, Chung T.; Nguyen, Nguyen D.; Nguyen, Quang Ngoc; Ni, Michael Y.; Nicolescu, Rodica; Nie, Peng; Nieto-Martínez, Ramfis E.; Nikitin, Yury P.; Ning, Guang; Ninomiya, Toshiharu; Nishi, Nobuo; Nishtar, Sania; Noale, Marianna; Noboa, Oscar A.; Nogueira, Helena; Nordendahl, Maria; Nordestgaard, Børge G.; Noto, Davide; Nowak-Szczepanska, Natalia; Nsour, Mohannad Al; Nuhoğlu, Irfan; Nunes, Baltazar; Nurk, Eha; Nuwaha, Fred; Nyirenda, Moffat; O’Neill, Terence W.; O’Reilly, Dermot; Obreja, Galina; Ochimana, Caleb; Ochoa-Avilés, Angélica M.; Oda, Eiji; Odili, Augustine N.; Oh, Kyungwon; Ohara, Kumiko; Ohlsson, Claes; Ohtsuka, Ryutaro; Olafsson, Örn; Olinto, Maria Teresa A.; Oliveira, Isabel O.; Omar, Mohd Azahadi; Omar, Saeed M.; Onat, Altan; Ong, Sok King; Onland-Moret, N. Charlotte; Ono, Lariane M.; Ordunez, Pedro; Ornelas, Rui; Ortiz, Ana P.; Ortiz, Pedro J.; Osler, Merete; Osmond, Clive; Ostojic, Sergej; Ostovar, Afshin; Otero, Johanna A.; Overvad, Kim; Owusu-Dabo, Ellis; Paccaud, Fred Michel; Pagkalos, Ioannis; Pahomova, Elena; de Paiva, Karina Mary; Pająk, Andrzej; Palloni, Alberto; Palmieri, Luigi; Pan, Wen-Harn; Panda-Jonas, Songhomitra; Pandey, Arvind; Panza, Francesco; Paoli, Mariela; Papadopoulou, Sousana K.; Papandreou, Dimitrios; Pareja, Rossina G.; Park, Soon-Woo; Park, Suyeon; Parnell, Winsome R.; Parsaeian, Mahboubeh; Pascanu, Ionela M.; Pasquet, Patrick; Patel, Nikhil D.; Pattussi, Marcos; Pavlyshyn, Halyna; Pechlaner, Raimund; Pećin, Ivan; Pednekar, Mangesh S.; Pedro, João M.; Peer, Nasheeta; Peixoto, Sergio Viana; Peltonen, Markku; Pereira, Alexandre C.; Peres, Marco A.; Pérez, Cynthia M.; Peterkova, Valentina; Peters, Annette; Petersmann, Astrid; Petkeviciene, Janina; Petrauskiene, Ausra; Kovtun, Olga Petrovna; Pettenuzzo, Emanuela; Peykari, Niloofar; Pfeiffer, Norbert; Phall, Modou Cheyassin; Pham, Son Thai; Pichardo, Rafael N.; Pierannunzio, Daniela; Pigeot, Iris; Pikhart, Hynek; Pilav, Aida; Pilotto, Lorenza; Pistelli, Francesco; Pitakaka, Freda; Piwonska, Aleksandra; Pizarro, Andreia N.; Plans-Rubió, Pedro; Platonova, Alina G.; Poh, Bee Koon; Pohlabeln, Hermann; Polka, Nadija S.; Pop, Raluca M.; Popovic, Stevo R.; Porta, Miquel; Posch, Georg; Poudyal, Anil; Poulimeneas, Dimitrios; Pouraram, Hamed; Pourfarzi, Farhad; Pourshams, Akram; Poustchi, Hossein; Pradeepa, Rajendra; Price, Alison J.; Price, Jacqueline F.; Prista, Antonio; Providencia, Rui; Puder, Jardena J.; Pudule, Iveta; Puiu, Maria; Punab, Margus; Qadir, Muhammed S.; Qasrawi, Radwan F.; Qorbani, Mostafa; Quintana, Hedley K.; Quiroga-Padilla, Pedro J.; Bao, Tran Quoc; Rach, Stefan; Radic, Ivana; Radisauskas, Ricardas; Rahimikazerooni, Salar; Rahman, Mahfuzar; Rahman, Mahmudur; Raitakari, Olli; Raj, Manu; Rajabov, Tamerlan; Rakhmatulloev, Sherali; Rakovac, Ivo; Rao, Sudha Ramachandra; Ramachandran, Ambady; Ramadan, Otim P. C.; Ramires, Virgílio V.; Ramke, Jacqueline; Ramos, Elisabete; Ramos, Rafel; Rampal, Lekhraj; Rampal, Sanjay; Rangelova, Lalka S.; Rarra, Vayia; Rascon-Pacheco, Ramon A.; Rech, Cassiano Ricardo; Redon, Josep; Reganit, Paul Ferdinand M.; Regecová, Valéria; Renner, Jane D. P.; Repasy, Judit A.; Reuter, Cézane P.; Revilla, Luis; Rezaianzadeh, Abbas; Rho, Yeunsook; Ribas-Barba, Lourdes; Ribeiro, Robespierre; Riboli, Elio; Richter, Adrian; Rigo, Fernando; Rigotti, Attilio; Rinaldo, Natascia; Rinke de Wit, Tobias F.; Rito, Ana I.; Ritti-Dias, Raphael M.; Rivera, Juan A.; Roa, Reina G.; Robinson, Louise; Robitaille, Cynthia; Roccaldo, Romana; Rodrigues, Daniela; Rodríguez-Artalejo, Fernando; del Cristo Rodriguez-Perez, María; Rodríguez-Villamizar, Laura A.; Rodríguez, Andrea Y.; Roggenbuck, Ulla; Rohloff, Peter; Rohner, Fabian; Rojas-Martinez, Rosalba; Rojroongwasinkul, Nipa; Romaguera, Dora; Romeo, Elisabetta L.; Rosario, Rafaela V.; Rosengren, Annika; Rouse, Ian; Rouzier, Vanessa; Roy, Joel G. R.; Ruano, Maira H.; Rubinstein, Adolfo; Rühli, Frank J.; Ruidavets, Jean-Bernard; Ruiz-Betancourt, Blanca Sandra; Ruiz-Castell, Maria; Moreno, Emma Ruiz; Rusakova, Iuliia A.; Jonsson, Kenisha Russell; Russo, Paola; Rust, Petra; Rutkowski, Marcin; Saamel, Marge; Sabanayagam, Charumathi; Sabbaghi, Hamideh; Sacchini, Elena; Sachdev, Harshpal S.; Sadjadi, Alireza; Safarpour, Ali Reza; Safi, Sare; Safiri, Saeid; Saghi, Mohammad Hossien; Saidi, Olfa; Saki, Nader; Šalaj, Sanja; Salanave, Benoit; Martinez, Eduardo Salazar; Saleva, Calogero; Salmerón, Diego; Salomaa, Veikko; Salonen, Jukka T.; Salvetti, Massimo; Samoutian, Margarita; Sánchez-Abanto, Jose; Rodríguez, Inés Sánchez; Sandjaja, NN; Sans, Susana; Marina, Loreto Santa; Santacruz, Ethel; Santos, Diana A.; Santos, Ina S.; Santos, Lèlita C.; Santos, Maria Paula; Santos, Osvaldo; Santos, Rute; Santos, Tamara R.; Saramies, Jouko L.; Sardinha, Luis B.; Sarrafzadegan, Nizal; Sathish, Thirunavukkarasu; Saum, Kai-Uwe; Savva, Savvas; Savy, Mathilde; Sawada, Norie; Sbaraini, Mariana; Scazufca, Marcia; Schaan, Beatriz D.; Rosario, Angelika Schaffrath; Schargrodsky, Herman; Schienkiewitz, Anja; Schindler, Karin; Schipf, Sabine; Schmidt, Carsten O.; Schmidt, Ida Maria; Schneider, Andrea; Schnohr, Peter; Schöttker, Ben; Schramm, Sara; Schramm, Stine; Schröder, Helmut; Schultsz, Constance; Schulze, Matthias B.; Schutte, Aletta E.; Sebert, Sylvain; Sedaghattalab, Moslem; Selamat, Rusidah; Sember, Vedrana; Sen, Abhijit; Senbanjo, Idowu O.; Sepanlou, Sadaf G.; Sequera, Guillermo; Serra-Majem, Luis; Servais, Jennifer; Ševčíková, Ľudmila; Shalnova, Svetlana; Shamah-Levy, Teresa; Shamshirgaran, Seyed Morteza; Shanthirani, Coimbatore Subramaniam; Sharafkhah, Maryam; Sharma, Sanjib K.; Shaw, Jonathan E.; Shayanrad, Amaneh; Shayesteh, Ali Akbar; Shengelia, Lela; Shi, Zumin; Shibuya, Kenji; Shimizu-Furusawa, Hana; Shimony, Tal; Shiri, Rahman; Shrestha, Namuna; Si-Ramlee, Khairil; Siani, Alfonso; Siantar, Rosalynn; Sibai, Abla M.; Sidossis, Labros S.; Silitrari, Natalia; Silva, Antonio M.; de Moura Silva, Caroline Ramos; Silva, Diego Augusto Santos; Silva, Kelly S.; Sim, Xueling; Simon, Mary; Simons, Judith; Simons, Leon A.; Sjöberg, Agneta; Sjöström, Michael; Skoblina, Natalia A.; Skodje, Gry Irene; Slazhnyova, Tatyana; Slowikowska-Hilczer, Jolanta; Slusarczyk, Przemysław; Smeeth, Liam; So, Hung-Kwan; Soares, Fernanda Cunha; Sobek, Grzegorz; Sobngwi, Eugène; Sodemann, Morten; Söderberg, Stefan; Soekatri, Moesijanti Y. 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Shyong; Tambalis, Konstantinos D.; Tammesoo, Mari-Liis; Tamosiunas, Abdonas; Tan, Eng Joo; Tang, Xun; Tanrygulyyeva, Maya; Tanser, Frank; Tao, Yong; Tarawneh, Mohammed Rasoul; Tarp, Jakob; Tarqui-Mamani, Carolina B.; Braunerová, Radka Taxová; Taylor, Anne; Taylor, Julie; Tchibindat, Félicité; te Velde, Saskia J.; Tebar, William R.; Tell, Grethe S.; Tello, Tania; Tham, Yih Chung; Thankappan, K.R.; Theobald, Holger; Theodoridis, Xenophon; Thomas, Nihal; Thorand, Barbara; Thuesen, Betina H.; Tichá, Ľubica; Timmermans, Erik J.; Tjandrarini, Dwi H.; Tjonneland, Anne; Tolonen, Hanna K.; Tolstrup, Janne S.; Topbas, Murat; Topór-Mądry, Roman; Torheim, Liv Elin; Tormo, María José; Tornaritis, Michael J.; Torrent, Maties; Torres-Collado, Laura; Toselli, Stefania; Touloumi, Giota; Traissac, Pierre; Tran, Thi Tuyet-Hanh; Tremblay, Mark S.; Triantafyllou, Areti; Trichopoulos, Dimitrios; Trichopoulou, Antonia; Trinh, Oanh T. 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Goya; Wareham, Nicholas; Weber, Adelheid; Webster-Kerr, Karen; Wedderkopp, Niels; Weghuber, Daniel; Wei, Wenbin; Weres, Aneta; Werner, Bo; Westbury, Leo D.; Whincup, Peter H.; Wickramasinghe, Kremlin; Widhalm, Kurt; Widyahening, Indah S.; Więcek, Andrzej; Wild, Philipp S.; Wilks, Rainford J.; Willeit, Johann; Willeit, Peter; Williams, Julianne; Wilsgaard, Tom; Wojciech, Rusek; Wojtyniak, Bogdan; Wolf, Kathrin; Wong-McClure, Roy A.; Wong, Andrew; Wong, Emily B.; Wong, Jyh Eiin; Wong, Tien Yin; Woo, Jean; Woodward, Mark; Wu, Frederick C.; Wu, Hon-Yen; Wu, Jianfeng; Wu, Li Juan; Wu, Shouling; Wyszyńska, Justyna; Xu, Haiquan; Xu, Liang; Yaacob, Nor Azwany; Yamborisut, Uruwan; Yan, Weili; Yang, Ling; Yang, Xiaoguang; Yang, Yang; Yardim, Nazan; Yasuharu, Tabara; García, Martha Yépez; Yiallouros, Panayiotis K.; Yngve, Agneta; Yoosefi, Moein; Yoshihara, Akihiro; You, Qi Sheng; You, San-Lin; Younger-Coleman, Novie O.; Yu, Yu-Ling; Yu, Yunjiang; Yusof, Safiah Md; Yusoff, Ahmad Faudzi; Zaccagni, Luciana; Zafiropulos, Vassilis; Zainuddin, Ahmad A.; Zakavi, Seyed Rasoul; Zamani, Farhad; Zambon, Sabina; Zampelas, Antonis; Zamrazilová, Hana; Zapata, Maria Elisa; Zargar, Abdul Hamid; Zaw, Ko Ko; Zayed, Ayman A.; Zdrojewski, Tomasz; Żegleń, Magdalena; Zejglicova, Kristyna; Vrkic, Tajana Zeljkovic; Zeng, Yi; Zhang, Luxia; Zhang, Zhen-Yu; Zhao, Dong; Zhao, Ming-Hui; Zhao, Wenhua; Zhecheva, Yanitsa V.; Zhen, Shiqi; Zheng, Wei; Zheng, Yingfeng; Zholdin, Bekbolat; Zhou, Maigeng; Zhu, Dan; Zins, Marie; Zitt, Emanuel; Zocalo, Yanina; Zoghlami, Nada; Cisneros, Julio Zuñiga; Zuziak, Monika; Bhutta, Zulfiqar A.; Black, Robert E.; Ezzati, Majid (Journal article; Peer reviewed, 2023)Optimal growth and development in childhood and adolescence is crucial for lifelong health and well-being1,2,3,4,5,6. Here we used data from 2,325 population-based studies, with measurements of height and weight from ... -
A global action agenda for turning the tide on fatty liver disease
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Ashworth; Dirchwolf, Melisa; Dufour, Jean-François; Dvorak, Karel; Ekstedt, Mattias; El-Kassas, Mohamed; Elsanousi, Osama M.; Elsharkawy, Ahmed M.; Elwakil, Reda M.; Eskridge, Wayne; Eslam, Mohammed; Esmat, Gamal; Fan, Jian-Gao; Ferraz, Maria Lucia; Flisiak, Robert; Fortin, Davide; Fouad, Yasser; Friedman, Scott L.; Fuchs, Michael; Gadano, Adrian; Geerts, Anja; Geier, Andreas; George, Jacob; Gerber, Lynn H.; Ghazinyan, Hasmik L.; Gheorghe, Liana; Kile, Denise Giangola; Girala, Marcos; Bee, George Goh Boon; Goossens, Nicolas; Graupera, Isabel; Grønbæk, Henning; Hamid, Saeed; Hebditch, Vanessa; Henry, Zachary; Hickman, Ingrid J.; Hobbs, L. Ansley; Hocking, Samantha L.; Hofmann, Wolf Peter; Idilman, Ramazan; Iruzubieta, Paula; Isaacs, Scott; Isakov, Vasily A.; Ismail, Mona H.; Jamal, Mohammad H.; Jarvis, Helen; Jepsen, Peter; Jornayvaz, François R.; Sudhamshu, K.C.; Kakizaki, Satoru; Karpen, Saul; Kawaguchi, Takumi; Keating, Shelley E.; Khader, Yousef; Kim, Seung Up; Kim, Won; Kleiner, David E.; Koek, Ger; Komas, Narcisse Patrice Joseph; Kondili, Loreta A.; Koot, Bart G.; Korenjak, Marko; Kotsiliti, Eleni; Koulla, Yiannoula; Kugelmas, Carina; Kugelmas, Marcelo; Labidi, Asma; Lange, Naomi F.; Lazo, Mariana; Leite, Nathalie; Lin, Han-Chieh; Lkhagvaa, Undram; Long, Michelle T.; Lopez-Jaramillo, Patricio; Lozano, Adelina; Macedo, Maria Paula; Malekzadeh, Reza; Marchesini, Giulio; Marciano, Sebastian; Martinez, Kim; Martínez Vázquez, Sophia E.; Mateva, Lyudmila; Mato, José M.; Mbendi, Charles N.; McCary, Alexis Gorden; McIntyre, Jeff; McKee, Martin; Mendive, Juan M.; Mikolasevic, Ivana; Miller, Pamela S.; Milovanovic, Tamara; Milton, Terri; Moreno-Alcantar, Rosalba; Morgan, Timothy R.; Motala, Ayesha A.; Muris, Jean; Musso, Carla; Nava-González, Edna J.; Negro, Francesco; Nersesov, Alexander V.; Neuschwander-Tetri, Brent A.; Nikolova, Dafina; Norris, Suzanne; Novak, Katja; Ocama, Ponsiano; Ong, Janus P.; Ong-Go, Arlinking; Onyekwere, Charles; Padilla-Machaca, P. Martin; Pais, Raluca; Pan, Calvin Q.; Panduro, Arturo; Panigrahi, Manas K.; Papatheodoridis, Georgios; Paruk, Imran; Patel, Keyur; Penha-Goncalves, Carlos; Pérez, Norma M.; Pérez-Escobar, Juanita; Pericàs, Juan M.; Perseghin, Gianluca; Pessoa, Mário Guimarães; Petta, Salvatore; de Oliveira, Claudia Pinto Marques Souza; Prabhakaran, Dorairaj; Pryke, Rachel; Pyrsopoulos, Nikolaos; Rabiee, Atoosa; Ramji, Alnoor; Ratziu, Vlad; Ravendhran, Natarajan; Ray, Katrina; Roden, Michael; Romeo, Stefano; Romero-Gómez, Manuel; Rotman, Yaron; Rouabhia, Samir; Rowe, Ian A.; Sadirova, Shakhlo; Alkhatry, Maryam Salem; Salupere, Riina; Satapathy, Sanjaya K.; Schwimmer, Jeffrey B.; Sebastiani, Giada; Seim, Lynn; Seki, Yosuke; Serme, Abdel Karim; Shapiro, David; Sharvadze, Lali; Shaw, Jonathan E.; Shawa, Isaac Thom; Shenoy, Thrivikrama; Shibolet, Oren; Shimakawa, Yusuke; Shubrook, Jay H.; Singh, Shivaram Prasad; Sinkala, Edford; Skladany, Lubomir; Skrypnyk, Igor; Song, Myeong Jun; Sookoian, Silvia; Soriano, Joan B.; Sridharan, Kannan; Stefan, Norbert; Stine, Jonathan G.; Stratakis, Nikos; Sheriff, Dhastagir Sultan; Sundaram, Shikha S.; Svegliati-Baroni, Gianluca; Swain, Mark G.; Tacke, Frank; Taheri, Shahrad; Tan, Soek-Siam; Tapper, Elliot B.; Targher, Giovanni; Tcaciuc, Eugen; Thiele, Maja; Tiniakos, Dina; Tolmane, Ieva; Torre, Aldo; Torres, Esther A.; Treeprasertsuk, Sombat; Trenell, Michael; Turcan, Svetlana; Turcanu, Adela; Valantinas, Jonas; van Kleef, Laurens A.; Velasco, Jose Antonio Velarde Ruiz; Vesterhus, Mette Nåmdal; Vilar-Gomez, Eduardo; Waked, Imam; Wattacheril, Julia; Wedemeyer, Heiner; Wilkins, Fonda; Willemse, José; Wong, Robert J.; Yilmaz, Yusuf; Yki-Järvinen, Hannele; Yu, Ming-Lung; Yumuk, Volkan; Zeybel, Müjdat; Zheng, Kenneth I.; Zheng, Ming-Hua (Journal article; Peer reviewed, 2024)Background and Aims: Fatty liver disease is a major public health threat due to its very high prevalence and related morbidity and mortality. Focused and dedicated interventions are urgently needed to target disease ... -
2-Deoxy-D-glucose couples mitochondrial DNA replication with mitochondrial fitness and promotes the selection of wild-type over mutant mitochondrial DNA
Pantic, Boris; Ives, Daniel; Mennuni, Mara; Perez-Rodriguez, Diego; Fernandez-Pelayo, Uxoa; Lopez de Arbina, Amaia; Muñoz-Oreja, Mikel; Villar-Fernandez, Marina; Dang, Thanh-mai Julie; Vergani, Lodovica; Johnston, Iain George; Pitceathly, Robert D. S.; McFarland, Robert; Hanna, Michael G.; Taylor, Robert W.; Holt, Ian J.; Spinazzola, Antonella (Journal article; Peer reviewed, 2021)Pathological variants of human mitochondrial DNA (mtDNA) typically co-exist with wild-type molecules, but the factors driving the selection of each are not understood. Because mitochondrial fitness does not favour the ...