• Big GABA II: Water-referenced edited MR spectroscopy at 25 research sites 

      Mikkelsen, Mark; Rimbault, Daniel L.; Barker, Peter B.; Bhattacharyya, Pallab K.; Brix, Maiken Kirkegaard; Buur, Pieter F.; Cecil, Kim M.; Chan, Kimberly L.; Chen, David Y.-T.; Craven, Alexander R.; Cuypers, Koen; Dacko, Michael; Duncan, Niall W.; Dydak, Ulrike; Edmondson, David A.; Ende, Gabriele; Ersland, Lars; Forbes, Megan A.; Gao, Fei; Greenhouse, Ian; Harris, Ashley D.; He, Naying; Heba, Stefanie; Hoggard, Nigel; Hsu, Tun-Wei; Jansen, Jacobus F.A.; Kangarlu, Alayar; Lange, Thomas; Lebel, R. Marc; Li, Yan; Lin, Chien-Yuan E.; Liou, Jy-Kang; Lirng, Jiing-Feng; Liu, Feng; Long, Joanna R.; Ma, Ruoyun; Maes, Celine; Moreno-Ortega, Marta; Murray, Scott O.; Noah, Sean; Noeske, Ralph; Noseworthy, Michael D.; Oeltzschner, Georg; Porges, Eric C.; Prisciandaro, James J.; Puts, Nicolaas A.J.; Roberts, Timothy P.L.; Sack, Markus; Sailasuta, Napapon; Saleh, Muhammad G.; Schallmo, Michael-Paul; Simard, Nicholas; Stoffers, Diederick; Swinnen, Stephan P.; Tegenthoff, Martin; Truong, Peter; Wang, Guangbin; Wilkinson, Iain D.; Wittsack, Hans-Jörg; Woods, Adam J.; Xu, Hongmin; Yan, Fuhua; Zhang, Chencheng; Zipunnikov, Vadim; Zöllner, Helge J.; Edden, Richard A.E. (Peer reviewed; Journal article, 2019)
      Accurate and reliable quantification of brain metabolites measured in vivo using 1H magnetic resonance spectroscopy (MRS) is a topic of continued interest. Aside from differences in the basic approach to quantification, ...
    • Default-mode network functional connectivity is closely related to metabolic activity 

      Passow, Susanne; Specht, Karsten; Adamsen, Tom Christian; Biermann, Martin; Brekke, Njål; Craig-Craven, Alexander Richard; Ersland, Lars; Grüner, Renate; Kleven-Madsen, Nina; Kvernenes, Ole Heine; Schwarzlmüller, Thomas; Olesen, Rasmus Aamand; Hugdahl, Kenneth (Peer reviewed; Journal article, 2015-06)
      Over the last decade, the brain's default-mode network (DMN) and its function has attracted a lot of attention in the field of neuroscience. However, the exact underlying mechanisms of DMN functional connectivity, or more ...
    • Dynamic up- and down-regulation of thedefault (DMN) and extrinsic (EMN) modenetworks during alternating task-on and task-offperiods 

      Hugdahl, Kenneth; Kazimierczak, Katarzyna Anna; Beresniewicz, Justyna; Kompus, Kristiina; Westerhausen, René; Ersland, Lars; Grüner, Renate; Specht, Karsten (Peer reviewed; Journal article, 2019)
      Using fMRI, Hugdahl et al. (2015) reported the existence of a general-domain cortical network during active task-processing which was non-specific to the cognitive task being processed. They labelled this network the ...
    • Intra-Regional Glu-GABA vs Inter-Regional Glu-Glu Imbalance: A 1H-MRS Study of the Neurochemistry of Auditory Verbal Hallucinations in Schizophrenia. 

      Hjelmervik, Helene; Craig-Craven, Alexander Richard; Sinkeviciute, Igne; Johnsen, Erik; Kompus, Kristiina; Bless, Josef Johann; Kroken, Rune Andreas; Løberg, Else-Marie; Ersland, Lars; Gruner, Eli Renate; Hugdahl, Kenneth (Peer reviewed; Journal article, 2019-10-18)
      Glutamate (Glu), gamma amino-butyric acid (GABA), and excitatory/inhibitory (E/I) imbalance have inconsistently been implicated in the etiology of schizophrenia. Elevated Glu levels in language regions have been suggested ...
    • Multi-vendor standardized sequence for edited magnetic resonance spectroscopy 

      Saleh, Muhammad G.; Rimbault, Daniel; Mikkelsen, Mark; Oeltzschner, Georg; Wang, Anna M; Jiang, Dengrong; Alhamud, Ali; Near, Jamie; Schär, Michael; Noeske, Ralph; Murdoch, James B; Ersland, Lars; Craven, Alexander R.; Dwyer, Gerard Eric; Grüner, Renate; Pan, Li; Ahn, Sinyeob; Edden, Richard A.E. (Peer reviewed; Journal article, 2019)
      Spectral editing allows direct measurement of low-concentration metabolites, such as GABA, glutathione (GSH) and lactate (Lac), relevant for understanding brain (patho)physiology. The most widely used spectral editing ...
    • No Effects of Anodal tDCS on Local GABA and Glx Levels in the Left Posterior Superior Temporal Gyrus 

      Dwyer, Gerard Eric; Craven, Alexander R.; Hirnstein, Marco; Kompus, Kristiina; Assmus, Jörg; Ersland, Lars; Hugdahl, Kenneth; Grüner, Renate (Peer reviewed; Journal article, 2019-01-08)
      A number of studies investigating the biological effects of transcranial direct current stimulation (tDCS) using magnetic resonance spectroscopy (MRS) have found that it may affect local levels of γ-aminobutyric acid (GABA), ...