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Bergen Open Research Archive

Browsing by Author "Enger, Per Øyvind"

Bergen Open Research Archive

Browsing by Author "Enger, Per Øyvind"

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  • Yang, Ning; Yan, Tao; Zhu, Huaiyang; Liang, Xiao; Leiss, Lina; Sakariassen, Per Øystein; Skaftnesmo, Kai Ove; Huang, Bin; Costea, Daniela Elena; Enger, Per Øyvind; Li, Xingang; Wang, Jian (Journal article, BioMed Central, 2014-10-04)
    Background: Although several studies suggest that stromal fibroblasts mediate treatment resistance in several cancer types, little is known about how tumor-associated astrocytes modulate the treatment response in brain ...
  • Brekke, Cecilie; Wang, Jian; Thuen, Marte; Gras Navarro, Andrea; Huuse-Røneid, Else Marie; Thorsen, Frits Alan; Poli, Aurélie; Zimmer, Jacques; Haraldseth, Olav; Lie, Stein Atle; Enger, Per Øyvind; Chekenya, Martha (Journal article, Public Library of Science, 2014-09-30)
    There are currently no established radiological parameters that predict response to immunotherapy. We hypothesised that multiparametric, longitudinal magnetic resonance imaging (MRI) of physiological parameters and ...
  • Kmiecik, Justyna; Poli, Aurélie; Brons, Nicolaas H.C.; Waha, Andreas; Eide, Geir Egil; Enger, Per Øyvind; Zimmer, Jacques; Chekenya, Martha (Peer reviewed; Journal article, Elsevier, 2013-11-15)
    We characterized GBM patients' tumor and systemic immune contexture with aim to reveal themechanisms of immunological escape, their impact on patient outcome, and identify targets for immunotherapy. Increased CD3+ T-cell ...
  • Svendsen, Agnete; Verhoeff, Joost J. C.; Immervoll, Heike; Brøgger, Jan C.; Kmiecik, Justyna; Poli, Aurélie; Netland, Inger A.; Planagumà, Jesús; Torsvik, Anja; Sakariassen, Per Øystein; Bjerkvig, Rolf; Enger, Per Øyvind; Tronstad, Karl Johan (Peer reviewed; Journal article, Springer, 2011-08-24)
    Glioblastoma (GBM) is a highly aggressive brain tumour, where patients respond poorly to radiotherapy and exhibit dismal survival outcomes. The mechanisms of radioresistance are not completely understood. However, cancer ...
  • Moen, Ingrid; Jevne, Alison Charlotte; Wang, Jian; Kalland, Karl-Henning; Chekenya, Martha; Akslen, Lars A.; Sleire, Linda; Enger, Per Øyvind; Reed, Rolf K.; Øyan, Anne Margrete; Stuhr, Linda Elin Birkhaug (Peer reviewed; Journal article, BioMed Central Ltd., 2012-01-17)
    Background The tumor microenvironment is pivotal in tumor progression. Thus, we aimed to develop a mammary tumor model to elucidate molecular characteristics in the stroma versus the tumor cell compartment ...
  • Yan, Tao; Skaftnesmo, Kai Ove; Leiss, Lina; Sleire, Linda; Wang, Jian; Li, Xingang; Enger, Per Øyvind (Journal article, BioMed Central, 2011-12-20)
    Background: Expression of neuronal elements has been identified in various glial tumors, and glioblastomas (GBMs) with neuronal differentiation patterns have reportedly been associated with longer survival. However, the ...
  • Yang, Ning; Huang, Bin; Tsinkalovsky, Oleg; Brekkå, Narve; Zhu, Huaiyang; Leiss, Lina; Enger, Per Øyvind; Li, Xingang; Wang, Jian (Journal article, BioMed Central, 2014-12-21)
    Backgroud: A key strategy for the study of the tumor microenvironment is to implant human tumor cells in an immunodeficient rodent strain ubiquitously expressing a fluorescent marker. Here, a novel nude rat expressing ...
  • Liang, Xiao; Osman, Tarig Al-Hadi; Sapkota, Dipak; Neppelberg, Evelyn; Lybak, Stein; Liavaag, Per Gunnar; Johannessen, Anne Christine; jacobsen, hk; Enger, Per Øyvind; Costea, Daniela Elena; Wang, Jian (Journal article, Elsevier, 2014-12)
    Background: Although several approaches for identification and isolation of carcinoma cells with tumour initiating properties have been established, enrichment of a population of pure and viable tumour-initiating cells ...
  • Wang, Jian; Miletic, Hrvoje; Sakariassen, Per Øystein; Huszthy, Peter Csaba; Jacobsen, Hege; Brekkå, Narve; Li, Xingang; Zhao, Peng; Mørk, Sverre; Chekenya, Martha; Bjerkvig, Rolf; Enger, Per Øyvind (Journal article, BioMed Central, 2009-12-29)
    Background: Establishing clinically relevant animal models of glioblastoma multiforme (GBM) remains a challenge, and many commonly used cell line-based models do not recapitulate the invasive growth patterns of patient ...
  • Poli, Aurélie; Wang, Jian; Domingues, Olivia; Planagumà, Jesús; Yan, Tao; Rygh, Cecilie Brekke; Skaftnesmo, Kai Ove; Thorsen, Frits Alan; McCormack, Emmet; Hentges, François; Pedersen, Paal-Henning; Zimmer, Jacques; Enger, Per Øyvind; Chekenya, Martha (Journal article, Impact Journals, 2013-09-09)
    Glioblastoma (GBM) is the most malignant brain tumor where patients’ survival is only 14.6 months, despite multimodal therapy with debulking surgery, concurrent chemotherapy and radiotherapy. There is an urgent, unmet ...
  • Wang, Jian; Svendsen, Agnete; Kmiecik, Justyna; Immervoll, Heike; Skaftnesmo, Kai Ove; Planagumà, Jesús; Reed, Rolf K.; Bjerkvig, Rolf; Miletic, Hrvoje; Enger, Per Øyvind; Rygh, Cecilie Brekke; Chekenya, Martha (Peer reviewed; Journal article, PLoS Computational Biology, 2011-07-29)
    Aberrant expression of the progenitor marker Neuron-glia 2 (NG2/CSPG4) or melanoma proteoglycan on cancer cells and angiogenic vasculature is associated with an aggressive disease course in several malignancies including ...

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